Search Results - "Greisler, Howard P."

Biomaterials in the development and future of vascular grafts by Xue, Lian, Greisler, Howard P.

“…Recent developments in the field of tissue engineering have re-invigorated the quest for more suitable biomaterials that are applicable to novel cardiovascular…”
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Biomimetic control of vascular smooth muscle cell morphology and phenotype for functional tissue-engineered small-diameter blood vessels by Chan-Park, Mary B., Shen, Jin Ye, Cao, Ye, Xiong, Yun, Liu, Yunxiao, Rayatpisheh, Shahrzad, Kang, Gavin Chun-Wei, Greisler, Howard P.

“…Small‐diameter blood vessel substitutes are urgently needed for patients requiring replacements of their coronary and below‐the‐knee vessels and for better…”
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In Vitro Models of Angiogenesis by Ucuzian, Areck A., Greisler, Howard P.

“…Neovascularization can be categorized into two general processes: vasculogenesis and angiogenesis. Angiogenesis is the formation of new capillaries from…”
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Characterization of type I collagen gels modified by glycation by Francis-Sedlak, Megan E, Uriel, Shiri, Larson, Jeffery C, Greisler, Howard P, Venerus, David C, Brey, Eric M

“…Abstract Chronic exposure to reducing sugars due to diabetes, aging, and diet can permanently modify extracellular matrix (ECM) proteins. This non-enzymatic…”
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Fibroblast Growth Factor-1 (FGF-1) Loaded Microbeads Enhance Local Capillary Neovascularization by Moya, Monica L., B.S, Garfinkel, Marc R., M.D, Liu, Xiang, M.D, Lucas, Stephanie, Opara, Emmanuel C., Ph.D, Greisler, Howard P., M.D, Brey, Eric M., Ph.D

“…Background Growth of new blood vessels (neovascularization) occurs naturally in the body, but the slow rate of the process may not be sufficient for survival…”
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Multilayered microcapsules for the sustained-release of angiogenic proteins from encapsulated cells by Khanna, Omaditya, Moya, Monica L., Ph.D, Greisler, Howard P., M.D, Opara, Emmanuel C., Ph.D, Brey, Eric M., Ph.D

“…Abstract Background Multilayered alginate microcapsules with a permselective poly-L-ornithine membrane can be used for the dual purpose of encapsulating cells…”
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There may be nothing new under the sun, but this is ridiculous by Brewster, Luke P., MD, Greisler, Howard P., MD

“…As an ad hoc reviewer for a vascular surgery journal, Dr X was asked to review a basic science submission. After she reviewed the manuscript, it became obvious…”
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Molecular Mediators of Angiogenesis by UCUZIAN, Areck A, GASSMAN, Andrew A, EAST, Andrea T, GREISLER, Howard P

“…Angiogenesis, or the formation of new blood vessels from the preexisting vasculature, is a key component in numerous physiologic and pathologic responses and…”
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Analyzer-based phase-contrast x-ray imaging of carotid plaque microstructure by Appel, Alyssa A., M.S, Chou, Cheng-Ying, Ph.D, Greisler, Howard P., M.D, Larson, Jeffery C., B.S, Vasireddi, Sunil, B.S, Zhong, Zhong, Ph.D, Anastasio, Mark A., Ph.D, Brey, Eric M., Ph.D

“…Abstract Background Plaque vulnerability depends, in part, on composition. Imaging techniques are needed that can aid the prediction of plaque stability…”
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Construction and characterization of a thrombin-resistant designer FGF-based collagen binding domain angiogen by Brewster, Luke P, Washington, Cicely, Brey, Eric M, Gassman, Andrew, Subramanian, Anu, Calceterra, Jen, Wolf, William, Hall, Connie L, Velander, William H, Burgess, Wilson H, Greisler, Howard P

“…Abstract Humans demonstrate limited spontaneous endothelialization of prosthetic bypass grafts. However the local application of growth factors to prosthetic…”
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Dynamic quantitative visualization of single cell alignment and migration and matrix remodeling in 3-D collagen hydrogels under mechanical force by Pang, Yonggang, Wang, Xiaoli, Lee, Dongkeun, Greisler, Howard P

“…Abstract We developed a live imaging system enabling dynamic visualization of single cell alignment induced by external mechanical force in a 3-D collagen…”
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Angiogenic endothelial cell invasion into fibrin is stimulated by proliferating smooth muscle cells by Ucuzian, Areck A., Bufalino, Dominick V., Pang, Yonggang, Greisler, Howard P.

“…These studies aimed to determine the effect of smooth muscle cells (SMCs) on angiogenic behavior of endothelial cells (ECs) within fibrin hydrogels, an…”
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Using a Type 1 Collagen-Based System to Understand Cell-Scaffold Interactions and to Deliver Chimeric Collagen-Binding Growth Factors for Vascular Tissue Engineering by Pang, Yonggang, Greisler, Howard P.

“…Vascular tissue engineering should provide more biocompatible and functional conduits than synthetic vascular grafts. Understanding cell-scaffold interactions…”
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Growing a living blood vessel: Insights for the second hundred years by Brewster, Luke P, Bufallino, Dominick, Ucuzian, Areck, Greisler, Howard P

“…Abstract Cardiovascular disease continues to be the leading cause of death worldwide, and the prevalence of cardiovascular disease has reached epidemic…”
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Sustained low levels of fibroblast growth factor-1 promote persistent microvascular network formation by Uriel, Shiri, Brey, Eric M., Greisler, Howard P.

“…Therapeutic neovascularization using high growth factor concentrations may lead to transient vessel formation and abnormal microvascular structure. The goal of…”
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Local delivery of a collagen-binding FGF-1 chimera to smooth muscle cells in collagen scaffolds for vascular tissue engineering by Pang, Yonggang, Wang, Xiaoli, Ucuzian, Areck A, Brey, Eric M, Burgess, Wilson H, Jones, Kathryn J, Alexander, Thomas D, Greisler, Howard P

“…Abstract We investigated the delivery of R136K–CBD (a collagen-binding mutant chimera of fibroblast growth factor-1) with a type I collagen scaffold as the…”
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Angiogenic effect of fibroblast growth factor-1 and vascular endothelial growth factor and their synergism in a novel in vitro quantitative fibrin-based 3-dimensional angiogenesis system by Xue, Lian, Greisler, Howard P.

“…Background. We have developed an in vitro 3-dimensional angiogenesis system in which the length, distribution, and ultrastructure of induced capillary sprouts…”
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Characterization of the chemotactic and mitogenic response of SMCs to PDGF-BB and FGF-2 in fibrin hydrogels by Ucuzian, Areck A., Brewster, Luke P., East, Andrea T., Pang, Yongang, Gassman, Andrew A., Greisler, Howard P.

“…The delivery of growth factors to cellularize biocompatible scaffolds like fibrin is a commonly used strategy in tissue engineering. We characterized smooth…”
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Paclitaxel inhibits ureteral smooth muscle cell proliferation and collagen production in the absence of cell toxicity by Will, Thomas A, Polcari, Anthony J, Garcia, Julia G, Ouwenga, Michael K, Voelzke, Bryan B, Greisler, Howard P, Turk, Thomas M T

“…Urinary tract stricture results from excess collagen deposition at an injured area. Paclitaxel (Sigma-Aldrich®) prevents coronary artery restenosis by…”
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The temporal and spatial dynamics of microscale collagen scaffold remodeling by smooth muscle cells by Pang, Yonggang, Ucuzian, Areck A, Matsumura, Akie, Brey, Eric M, Gassman, Andrew A, Husak, Vicki A, Greisler, Howard P

“…Abstract Smooth muscle cells (SMCs) and collagen scaffolds are widely used in vascular tissue engineering but their interactions in remodeling at the…”
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