Search Results - "Greisen, Stinne R."

Co-Inhibitory Molecules – Their Role in Health and Autoimmunity; Highlighted by Immune Related Adverse Events by Greisen, Stinne R., Aspari, Maithri, Deleuran, Bent

“…Immune checkpoint receptors are key players in regulating the immune response. They are responsible for both generating an immune response sufficient to kill…”
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CXCL13 predicts long-term radiographic status in early rheumatoid arthritis by Greisen, Stinne R, Mikkelsen, Clara, Hetland, Merete L, Østergaard, Mikkel, Hørslev-Petersen, Kim, Junker, Peter, Stengaard-Petersen, Kristian, Deleuran, Bent

“…Abstract Objectives Identification of RA patients at a high risk of joint destruction remains challenging. The C-X-C motif chemokine 13 (CXCL13) has previously…”
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The Programmed Death-1 Pathway Counter-Regulates Inflammation-Induced Osteoclast Activity in Clinical and Experimental Settings by Greisen, Stinne R, Kragstrup, Tue W, Thomsen, Jesper Skovhus, Hørslev-Pedersen, Kim, Hetland, Merete Lund, Stengaard-Pedersen, Kristian, Østergaard, Mikkel, Ørnbjerg, Lykke, Junker, Peter, Sharpe, Arlene H, Freeman, Gordon J, Hvid, Malene, Moestrup, Søren K, Hauge, Ellen Margrethe, Deleuran, Bent

“…The programmed death-1 (PD-1) pathway is essential for maintaining self-tolerance and plays an important role in autoimmunity, including rheumatoid arthritis…”
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Extracellular Vesicles Transfer the Receptor Programmed Death-1 in Rheumatoid Arthritis by Greisen, Stinne R, Yan, Yan, Hansen, Aida S, Venø, Morten T, Nyengaard, Jens R, Moestrup, Søren K, Hvid, Malene, Freeman, Gordon J, Kjems, Jørgen, Deleuran, Bent

“…Extracellular vesicles (EVs) have been recognized as route of communication in the microenvironment. They transfer proteins and microRNAs (miRNAs) between…”
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Spontaneous generation of functional osteoclasts from synovial fluid mononuclear cells as a model of inflammatory osteoclastogenesis by Greisen, Stinne R., Einarsson, Halldór Bjarki, Hvid, Malene, Hauge, Ellen-Margrethe, Deleuran, Bent, Kragstrup, Tue Wenzel

“…In osteoimmunology, osteoclastogenesis is understood in the context of the immune system. Today, the in vitro model for osteoclastogenesis necessitates the…”
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Programmed death ligand 2 – A link between inflammation and bone loss in rheumatoid arthritis by Greisen, Stinne R., Kragstrup, Tue W., Thomsen, Jesper Skovhus, Hansen, Aida Solhøj, Krishnamurthy, Akilan, Hørslev-Petersen, Kim, Hetland, Merete Lund, Stengaard-Pedersen, Kristian, Østergaard, Mikkel, Ørnbjerg, Lykke Midtbøll, Junker, Peter, Sharpe, Arlene H., Freeman, Gordon J., Annamalai, Lakshmanan, Hvid, Malene, Moestrup, Søren K., Hauge, Ellen-Margrethe, Catrina, Anca Irinel, Deleuran, Bent

“…Active rheumatoid arthritis (RA) is accompanied by increased appendicular and axial bone loss, closely associated to the degree of inflammation. The programmed…”
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Soluble programmed death-1 levels are associated with disease activity and treatment response in patients with autoimmune hepatitis by Aarslev, Kristian, Dige, Anders, Greisen, Stinne R., Kreutzfeldt, Martin, Jessen, Niels, Vilstrup, Hendrik, Deleuran, Bent, Grønbæk, Henning

“…Purpose: Autoimmune hepatitis (AIH) is a chronic liver disease caused by impaired immune regulation. Programmed death-1 (PD-1) is an inhibitory receptor mainly…”
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Clonally expanded CD38 hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis by Wang, Runci, Singaraju, Anvita, Marks, Kathryne E, Shakib, Lorien, Dunlap, Garrett, Adejoorin, Ifeoluwakiisi, Greisen, Stinne R, Chen, Lin, Tirpack, Aidan K, Aude, Carlos, Fein, Miriam R, Todd, Derrick J, MacFarlane, Lindsey, Goodman, Susan M, DiCarlo, Edward F, Massarotti, Elena M, Sparks, Jeffrey A, Jonsson, A Helena, Brenner, Michael B, Postow, Michael A, Chan, Karmela K, Bass, Anne R, Donlin, Laura T, Rao, Deepak A

“…Immune checkpoint inhibitor (ICI) therapies used to treat cancer, such as anti-PD-1 antibodies, can induce autoimmune conditions in some individuals. The T…”
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