Search Results - "Greisen, Per J"

Computational design of environmental sensors for the potent opioid fentanyl by Bick, Matthew J, Greisen, Per J, Morey, Kevin J, Antunes, Mauricio S, La, David, Sankaran, Banumathi, Reymond, Luc, Johnsson, Kai, Medford, June I, Baker, David

“…We describe the computational design of proteins that bind the potent analgesic fentanyl. Our approach employs a fast docking algorithm to find shape…”
Get full text

Improving the Developability of an Antigen Binding Fragment by Aspartate Substitutions by Sakhnini, Laila I, Greisen, Per J, Wiberg, Charlotte, Bozoky, Zoltan, Lund, Søren, Wolf Perez, Adriana-Michelle, Karkov, Hanne S, Huus, Kasper, Hansen, Jens-Jacob, Bülow, Leif, Lorenzen, Nikolai, Dainiak, Maria B, Pedersen, Anja K

“…Aggregation can be a major challenge in the development of antibody-based pharmaceuticals as it can compromise the quality of the product during bioprocessing,…”
Get full text

Optimizing selectivity of anion hydrophobic multimodal chromatography for purification of a single‐chain variable fragment by Sakhnini, Laila I., Pedersen, Anja K., León, Ileana Rodríguez, Greisen, Per J., Hansen, Jens Jacob, Vester‐Christensen, Malene B., Bülow, Leif, Dainiak, Maria B.

“…Single‐chain variable fragments (scFv) are widely used in several fields. However, they can be challenging to purify unless using expensive Protein L‐based…”
Get full text

A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice by Østergaard, Henrik, Lund, Jacob, Greisen, Per J., Kjellev, Stine, Henriksen, Anette, Lorenzen, Nikolai, Johansson, Eva, Røder, Gustav, Rasch, Morten G., Johnsen, Laust B., Egebjerg, Thomas, Lund, Søren, Rahbek-Nielsen, Henrik, Gandhi, Prafull S., Lamberth, Kasper, Loftager, Mette, Andersen, Lisbeth M., Bonde, Amalie C., Stavenuiter, Fabian, Madsen, Daniel E., Li, Xun, Holm, Thomas L., Ley, Carsten D., Thygesen, Peter, Zhu, Haisun, Zhou, Rong, Thorn, Karina, Yang, Zhiru, Hermit, Mette B., Bjelke, Jais R., Hansen, Bjarne G., Hilden, Ida

“…Hemophilia A is a bleeding disorder resulting from deficient factor VIII (FVIII), which normally functions as a cofactor to activated factor IX (FIXa) that…”
Get full text

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis by Khare, Sagar D, Kipnis, Yakov, Greisen, Per Jr, Takeuchi, Ryo, Ashani, Yacov, Goldsmith, Moshe, Song, Yifan, Gallaher, Jasmine L, Silman, Israel, Leader, Haim, Sussman, Joel L, Stoddard, Barry L, Tawfik, Dan S, Baker, David

“…Metals serve as unique structural and functional elements in biology, providing a wealth of reactivities not available in a wholly proteinogenic active site…”
Get full text

Qm Simulation Of Binding Site In P-type Atpases by Greisen, Per J.

Get full text

Interaction between sodium dodecyl sulfate and membrane reconstituted aquaporins: A comparative study of spinach SoPIP2;1 and E. coli AqpZ by Hansen, Jesper S., Vararattanavech, Ardcharaporn, Plasencia, Inés, Greisen, Per Jr, Bomholt, Julie, Torres, Jaume, Emnéus, Jenny, Hélix-Nielsen, Claus

“…This study describes the interaction between sodium dodecyl sulfate (SDS) and membrane proteins reconstituted into large unilamellar lipid vesicles and…”
Get full text

PH.D Student by Greisen, Per J., Lum, Kevin, Andersen, Olaf S, August Lundbæk, Jens

Get full text