Search Results - "Greischar, Megan"

Modern Epidemics: From the Spanish Flu to COVID-19 by Greischar, Megan A.

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Proliferation in malaria parasites: how resource limitation can prevent evolution of greater virulence by Pak, Damie, Kamiya, Tsukushi, Greischar, Megan A

“…For parasites, robust proliferation within hosts is crucial for establishing the infection and creating opportu- nities for onward transmission. While faster…”
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Modern Epidemics: From the Spanish Flu to COVID-19 by Greischar, Megan A.

“…Modern Epidemics is written with lay readers in mind, so diseases are grouped by relevance to humans—for instance microbes with bioterrorist potential—rather…”
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synthesis of experimental work on parasite local adaptation by Greischar, Megan A, Koskella, Britt

“…The study of parasite local adaptation, whereby parasites perform better on sympatric hosts than on allopatric hosts and/or better on their own host population…”
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Adaptive plasticity in the gametocyte conversion rate of malaria parasites by Schneider, Petra, Greischar, Megan A, Birget, Philip L G, Repton, Charlotte, Mideo, Nicole, Reece, Sarah E

“…Sexually reproducing parasites, such as malaria parasites, experience a trade-off between the allocation of resources to asexual replication and the production…”
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Extraordinary parasite multiplication rates in human malaria infections by Greischar, Megan A., Childs, Lauren M.

“…Theory assumes that multiplication rates of pathogenic organisms have substantial influence on disease severity and spread.Malaria infections represent one of…”
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Uncovering drivers of dose-dependence and individual variation in malaria infection outcomes by Kamiya, Tsukushi, Greischar, Megan A, Schneider, David S, Mideo, Nicole

“…To understand why some hosts get sicker than others from the same type of infection, it is essential to explain how key processes, such as host responses to…”
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Linking functional and molecular mechanisms of host resilience to malaria infection by Kamiya, Tsukushi, Davis, Nicole M, Greischar, Megan A, Schneider, David, Mideo, Nicole

“…It remains challenging to understand why some hosts suffer severe illnesses, while others are unscathed by the same infection. We fitted a mathematical model…”
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Anthropogenic nest sites provide warmer incubation environments than natural nest sites in a population of oviparous reptiles near their northern range limit by Francis, Elizabeth Ann, Moldowan, Patrick D., Greischar, Megan A., Rollinson, Njal

“…Oviposition site choice affects a host of offspring phenotypes and directly impacts maternal fitness. Recent evidence suggests that oviparous reptiles often…”
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Epidemiological consequences of immune sensitisation by pre-exposure to vector saliva by Kamiya, Tsukushi, Greischar, Megan A, Mideo, Nicole

“…Blood-feeding arthropods-like mosquitoes, sand flies, and ticks-transmit many diseases that impose serious public health and economic burdens. When a…”
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The Challenge of Quantifying Synchrony in Malaria Parasites by Greischar, Megan A., Reece, Sarah E., Savill, Nicholas J., Mideo, Nicole

“…Malaria infection is often accompanied by periodic fevers, triggered by synchronous cycles of parasite replication within the host. The degree of synchrony in…”
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Quantifying Transmission Investment in Malaria Parasites by Greischar, Megan A, Mideo, Nicole, Read, Andrew F, Bjørnstad, Ottar N

“…Many microparasites infect new hosts with specialized life stages, requiring a subset of the parasite population to forgo proliferation and develop into…”
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Mistimed malaria parasites re‐synchronize with host feeding‐fasting rhythms by shortening the duration of intra‐erythrocytic development by O’Donnell, Aidan J., Greischar, Megan A., Reece, Sarah E.

“…Aims Malaria parasites exhibit daily rhythms in the intra‐erythrocytic development cycle (IDC) that underpins asexual replication in the blood. The IDC…”
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Challenges in forming inferences from limited data: a case study of malaria parasite maturation by Peters, Madeline A E, Greischar, Megan A, Mideo, Nicole

“…Inferring biological processes from population dynamics is a common challenge in ecology, particularly when faced with incomplete data. This challenge extends…”
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Partitioning the influence of ecology across scales on parasite evolution by Greischar, Megan A., Beck-Johnson, Lindsay M., Mideo, Nicole

“…Vector-borne parasites must succeed at three scales to persist: they must proliferate within a host, establish in vectors, and transmit back to hosts. Ecology…”
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Temperature-dependent variation in the extrinsic incubation period elevates the risk of vector-borne disease emergence by Kamiya, Tsukushi, Greischar, Megan A., Wadhawan, Kiran, Gilbert, Benjamin, Paaijmans, Krijn, Mideo, Nicole

“…•Extrinsic incubation period variation elevates vector-borne disease risk.•Per Jensen's Inequality fast incubation contributes disproportionately to…”
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Environmental variability affects optimal trade‐offs in ecological immunology by Kirk, Devin, Greischar, Megan, Mideo, Nicole, Krkošek, Martin

“…The costs of mounting and maintaining an immune response lead to trade‐offs with investment in (or maintenance of) other organ systems or functions such as…”
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The role of models in translating within-host dynamics to parasite evolution by Greischar, Megan A, Reece, Sarah E, Mideo, Nicole

“…Mathematical modelling provides an effective way to challenge conventional wisdom about parasite evolution and investigate why parasites 'do what they do'…”
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Predicting optimal transmission investment in malaria parasites by Greischar, Megan A., Mideo, Nicole, Read, Andrew F., Bjørnstad, Ottar N.

“…In vertebrate hosts, malaria parasites face a tradeoff between replicating and the production of transmission stages that can be passed onto mosquitoes. This…”
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Altered life history strategies protect malaria parasites against drugs by Birget, Philip L. G., Greischar, Megan A., Reece, Sarah E., Mideo, Nicole

“…Drug resistance has been reported against all antimalarial drugs, and while parasites can evolve classical resistance mechanisms (e.g., efflux pumps), it is…”
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