Search Results - "Greiner, Erich F."
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The Epithelial Glucocorticoid Receptor Is Required for the Normal Timing of Cell Proliferation during Mammary Lobuloalveolar Development but Is Dispensable for Milk Production
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2005)“…Glucocorticoids have been shown to influence mammary gland function in vivo and to stimulate milk protein gene expression in vitro. Here, we describe the…”
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Vaccination with Designed Neopeptides Induces Intratumoral, Cross-reactive CD4+ T-cell Responses in Glioblastoma
Published in Clinical cancer research (15-12-2022)“…The low mutational load of some cancers is considered one reason for the difficulty to develop effective tumor vaccines. To overcome this problem, we developed…”
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TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development
Published in The Journal of clinical investigation (01-01-2008)“…TRAIL is a promising anticancer agent due to its ability to selectively induce apoptosis in established tumor cell lines but not nontransformed cells. Herein,…”
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Differential Ligand-Dependent Protein-Protein Interactions between Nuclear Receptors and a Neuronal-Specific Cofactor
Published in Proceedings of the National Academy of Sciences - PNAS (20-06-2000)“…Nuclear receptors are transcription factors that require multiple protein-protein interactions to regulate target gene expression. We have cloned a 27-kDa…”
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Evaluation of steroid receptor function by gene targeting in mice
Published in Journal of steroid biochemistry and molecular biology (01-02-2005)“…Corticosteroid hormones regulate a variety of developmental, physiological and pathological processes via their cognate receptors, the glucocorticoid receptor…”
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Targeting mammary epithelial cells using a bacterial artificial chromosome
Published in Genesis (New York, N.Y. : 2000) (01-07-2002)“…We describe the generation of transgenic mouse lines expressing Cre recombinase in epithelial cells of the lactating mammary gland. As an expression vector, we…”
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Functional Analysis of Retinoid Z Receptor $\beta $, a Brain-Specific Nuclear Orphan Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (17-09-1996)“…The retinoid Z receptor $\beta $ (RZR$\beta $), an orphan receptor, is a member of the retinoic acid receptor (RAR)/thyroid hormone receptor (TR) subfamily of…”
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Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production
Published in The Journal of biological chemistry (16-12-1994)“…A transition from aerobic to anaerobic metabolism occurs as mitogen-activated thymocytes undergo proliferation. Glucose utilization and lactate formation…”
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