Search Results - "Greig, Chasen J."

Muscarinic acetylcholine receptors participate in small intestinal mucosal homeostasis by Greig, Chasen J, Cowles, Robert A

“…Abstract Background Intestinal mucosal homeostasis is controlled by multiple factors and an intact, functional mucosa is essential for survival. Maintenance of…”
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The M1 muscarinic acetylcholine receptor in the crypt stem cell compartment mediates intestinal mucosal growth by Greig, Chasen J, Armenia, Sarah J, Cowles, Robert A

“…Maintenance of the highly plastic intestinal epithelium relies upon stem cells localized to intestinal crypts. Recent evidence suggests muscarinic…”
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Potentiation of serotonin signaling leads to increased carbohydrate and lipid absorption in the murine small intestine by Park, Christine J., Armenia, Sarah J., Shaughnessy, Matthew P., Greig, Chasen J., Cowles, Robert A.

“…Enteric serotonin influences intestinal homeostasis and functions as a mucosal growth factor. Previously, we demonstrated increased mucosal surface area and…”
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Potentiated serotonin signaling in serotonin re‐uptake transporter knockout mice increases enterocyte mass and small intestinal absorptive function by Greig, Chasen J., Zhang, Lucy, Cowles, Robert A.

“…Genetic knockout of the serotonin reuptake transporter (SERT) potentiates serotonin signaling and increases crypt‐cell proliferation, neuroplasticity, and…”
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Enhanced serotonin signaling increases intestinal neuroplasticity by Greig, Chasen J., MD, Gandotra, Neeru, PhD, Tackett, John J., MD, MHS, Bamdad, Michaela C., BA, Cowles, Robert A., MD, FACS, FAAP

“…Abstract Background The intestinal mucosa recovers from injury by accelerating enterocyte proliferation resulting in villus growth. A similar phenomenon is…”
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Retracing our STEPs: Four decades of progress in intestinal lengthening procedures for short bowel syndrome by Greig, Chasen J., Oh, Pilyung S., Gross, Erica R., Cowles, Robert A.

“…The surgical management of intestinal failure secondary to short bowel syndrome has undergone tremendous evolution in the last several decades. From the…”
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Orally Dosed Citalopram Stimulates Small Intestinal Mucosal Growth by Zhang, Lucy, Greig, Chasen J., Cowles, Robert A.

“…Parenterally administered selective serotonin reuptake inhibitors, such as citalopram, increase intestinal mucosal absorptive surface by day 7 of treatment. We…”
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Mucosal homeostasis is altered in the ileum of gnotobiotic mice by Greig, Chasen J., Alper, Arik, Goodman, Andrew L., Cowles, Robert A.

“…The microbiome of the gastrointestinal tract is a vast collection of microorganisms implicated in numerous aspects of normal physiology and disease…”
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Improved capacity to evaluate changes in intestinal mucosal surface area using mathematical modeling by Greig, Chasen J., Cowles, Robert A.

“…Quantification of intestinal mucosal growth typically relies on morphometric parameters, commonly villus height, as a surrogate for presumed changes in mucosal…”
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The Impact of Pediatric Surgical Specialty Meetings: A 5-year Analysis of Presented Abstracts by Greig, Chasen J., Zhang, Lucy, Armenia, Sarah J., Park, Christine J., Fischer, Anne C., Caty, Michael G., Cowles, Robert A.

“…Abstracts presented at the American Academy of Pediatrics Section on Surgery (AAP) and American Pediatric Surgical Association (APSA) meetings can be taken as…”
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Routine postnatal chest x-ray and intensive care admission are unnecessary for a majority of infants with congenital lung malformations by Greig, Chasen J., Keiser, Amaris M., Cleary, Muriel A., Stitelman, David H., Christison-Lagay, Emily R., Ozgediz, Doruk E., Solomon, Daniel G., Caty, Michael G., Cowles, Robert A.

“…Postnatal evaluation of prenatally identified congenital lung malformations (CLMs) often includes a chest x-ray (CXR) and neonatal intensive care unit (NICU)…”
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Chest wall injury fracture patterns are associated with different mechanisms of injury: a retrospective review study in the United States by Brewer, Jennifer M, Karsmarski, Owen P, Fridling, Jeremy, Hill, T Russell, Greig, Chasen J, Posillico, Sarah E, McGuiness, Carol, McLaughlin, Erin, Montgomery, Stephanie C, Moutinho, Manuel, Gross, Ronald, Eriksson, Evert A, Doben, Andrew R

“…Research on rib fracture management has exponentially increased. Predicting fracture patterns based on the mechanism of injury (MOI) and other possible…”
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Serotonin Reuptake Transporter Knockout Mice Exhibit Increased Enterocyte Mass and Intestinal Glucose Absorption by Greig, Chasen J., Zhang, Lucy, Cowles, Robert A.

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