Search Results - "Gregory, Nicholas"
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Regular physical activity prevents chronic pain by altering resident muscle macrophage phenotype and increasing interleukin-10 in mice
Published in Pain (Amsterdam) (01-01-2016)“…Regular physical activity in healthy individuals prevents development of chronic musculoskeletal pain; however, the mechanisms underlying this exercise-induced…”
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The dichotomized role for acid sensing ion channels in musculoskeletal pain and inflammation
Published in Neuropharmacology (01-07-2015)“…Chronic muscle pain affects between 11 and 24% of the world's population with the majority of people experiencing musculoskeletal pain at some time in their…”
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Acid Sensing Ion Channel 1a (ASIC1a) Mediates Activity-induced Pain by Modulation of Heteromeric ASIC Channel Kinetics
Published in Neuroscience (21-08-2018)“…•Activity-induced hyperalgesia is prevented by blockade of ASIC1a with psalmotoxin, but not by genetic deletion of ASIC1a.•Psalmotoxin alters kinetics of…”
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An overview of animal models of pain: disease models and outcome measures
Published in The journal of pain (01-11-2013)“…Pain is ultimately a perceptual phenomenon. It is built from information gathered by specialized pain receptors in tissue, modified by spinal and supraspinal…”
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Effect of Intramuscular Protons, Lactate, and ATP on Muscle Hyperalgesia in Rats
Published in PloS one (17-09-2015)“…Chronic muscle pain is a significant health problem leading to disability[1]. Muscle fatigue can exacerbate muscle pain. Metabolites, including ATP, lactate,…”
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P2X4 Receptors on Muscle Macrophages Are Required for Development of Hyperalgesia in an Animal Model of Activity-Induced Muscle Pain
Published in Molecular neurobiology (01-04-2020)“…Activity-induced pain is common in those with chronic musculoskeletal pain and limits participation in daily activities and exercise. Our laboratory developed…”
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Statistical learning shapes pain perception and prediction independently of external cues
Published in eLife (10-07-2024)“…The placebo and nocebo effects highlight the importance of expectations in modulating pain perception, but in everyday life we don't need an external source of…”
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Fatigue-enhanced hyperalgesia in response to muscle insult: Induction and development occur in a sex-dependent manner
Published in Pain (Amsterdam) (01-12-2013)“…Characterization of a pre-clinical model of chronic muscle pain in which muscle fatigue combined with a subthreshold muscle insult produces long-lasting,…”
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Peripheral Nerve Stimulation for Pudendal Neuralgia: A Technical Note
Published in Pain medicine (Malden, Mass.) (01-08-2020)“…Abstract Background Pudendal neuropathy is a chronic, disabling form of perineal pain that involves the pudendal nerve, a mixed somatic and autonomic nerve…”
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ASIC3 Is Required for Development of Fatigue-Induced Hyperalgesia
Published in Molecular neurobiology (01-03-2016)“…An acute bout of exercise can exacerbate pain, hindering participation in regular exercise and daily activities. The mechanisms underlying pain in response to…”
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Preoperative cigarette smoking and short-term morbidity and mortality after cardiac surgery: a meta-analysis
Published in Heart Asia (01-10-2018)“…Currently, the choice of whether or not to electively operate on current smokers is varied among cardiothoracic surgeons. This meta-analysis aims to determine…”
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2672 Gastric Amyloidosis: A Rare Cause of Gastropathy and GI Bleeding
Published in The American journal of gastroenterology (01-10-2019)“…INTRODUCTION: Amyloidosis is a disorder of protein deposition that often presents with systemic symptoms. Symptoms of GI amyloidosis include abdominal pain,…”
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Defending the One Percent
Published in The Journal of economic perspectives (01-07-2013)“…Imagine a society with perfect economic equality. Then, one day, this egalitarian utopia is disturbed by an entrepreneur with an idea for a new product. Think…”
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Lifting the Lid on CAPS: Uncovering Genetic Anticipation in Cryopyrin-Associated Periodic Syndrome
Published in Clinical immunology (Orlando, Fla.) (01-05-2023)“…Cryopyrin-associated periodic syndrome (CAPS) is a spectrum of autoinflammatory conditions comprising three subtypes: familial cold autoinflammatory syndrome…”
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THE RAPID PROGRESSION OF EMPHYSEMA IN A PATIENT RECOVERING FROM COVID-19
Published in Chest (01-10-2024)Get full text
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Stent-Assisted Balloon-Induced Intimal Disruption and Relamination in Aortic Dissection Repair (STABILISE): A Meta-Analysis of Early Outcomes
Published in Annals of vascular surgery (01-01-2024)“…This meta-analysis aims to determine the early clinical outcomes and rate of complete false lumen obliteration associated with the stent-assisted…”
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Induction of asthma causes sensitization of the carotid bodies to lysophosphatidic acid
Published in The FASEB journal (01-04-2019)“…Previously, we demonstrated an important role for the carotid bodies in asthmatic bronchoconstriction. Specifically, we showed that an allergen‐induced…”
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Friedman's Presidential Address in the Evolution of Macroeconomic Thought
Published in The Journal of economic perspectives (01-01-2018)“…Milton Friedman's presidential address, “The Role of Monetary Policy,” which was delivered 50 years ago in December 1967 and published in the March 1968 issue…”
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Market Power in Neoclassical Growth Models
Published in The Review of economic studies (06-03-2023)“…Abstract This article examines the optimal accumulation of capital and the effects of government debt in neoclassical growth models in which firms have market…”
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