Search Results - "Gregory, C A"
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Environmental barcoding: a next-generation sequencing approach for biomonitoring applications using river benthos
Published in PloS one (13-04-2011)“…Timely and accurate biodiversity analysis poses an ongoing challenge for the success of biomonitoring programs. Morphology-based identification of bioindicator…”
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Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels
Published in Gut pathogens (04-01-2020)“…Inflammatory bowel disease (IBD), is a debilitating group of chronic diseases including Crohn's Disease (CD) and ulcerative colitis (UC), which causes…”
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Metagenomic characterisation of canine skin reveals a core healthy skin microbiome
Published in Scientific reports (29-08-2024)“…Furthering our knowledge of the skin microbiome is essential to understand health and disease in canines. To date, studies into the canine skin microbiome have…”
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The widespread dissemination of integrons throughout bacterial communities in a riverine system
Published in The ISME Journal (01-03-2018)“…Anthropogenic inputs increase levels of antimicrobial resistance (AMR) in the environment, however, it is unknown how these inputs create this observed…”
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Impact of acute stress on the canine gut microbiota
Published in Scientific reports (14-08-2024)“…There is growing evidence that a relationship exists between mental and emotional wellbeing and the gut microbiota. Little is known regarding how the…”
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Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2017)“…Bacterial natural products remain an important source of new medicines. DNA sequencing has revealed that a majority of natural product biosynthetic gene…”
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A universal DNA mini-barcode for biodiversity analysis
Published in BMC genomics (12-05-2008)“…The goal of DNA barcoding is to develop a species-specific sequence library for all eukaryotes. A 650 bp fragment of the cytochrome c oxidase 1 (CO1) gene has…”
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Conserved signatures of the canine faecal microbiome are associated with metronidazole treatment and recovery
Published in Scientific reports (04-03-2024)“…Antibiotic resistance is recognised as one of the biggest global threats to human and animal health. Understanding the influence of antibiotics on the canine…”
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Developing standards for the microbiome field
Published in Microbiome (26-06-2020)“…Effective standardisation of methodologies to analyse the microbiome is essential to the entire microbiome community. Despite the microbiome field being…”
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Exploring how microbiome signatures change across inflammatory bowel disease conditions and disease locations
Published in Scientific reports (21-09-2021)“…Understanding the variables that influence microbiome studies is critical for successful translational research. Inflammatory bowel disease (IBD) is a complex…”
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DNA barcoding: how it complements taxonomy, molecular phylogenetics and population genetics
Published in Trends in genetics (01-04-2007)“…DNA barcoding aims to provide an efficient method for species-level identifications and, as such, will contribute powerfully to taxonomic and biodiversity…”
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A Salivary Gland Resident Macrophage Subset Regulating Radiation Responses
Published in Journal of dental research (01-05-2023)“…Radiotherapy of head and neck cancers frequently leads to irreversible hypofunction of salivary glands, which severely compromises the quality of life and is…”
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Validated predictive modelling of the environmental resistome
Published in The ISME Journal (01-06-2015)“…Multi-drug-resistant bacteria pose a significant threat to public health. The role of the environment in the overall rise in antibiotic-resistant infections…”
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NAMERS: a purpose-built reference DNA sequence database to support applied eDNA metabarcoding
Published in Metabarcoding and Metagenomics (19-11-2024)“…Applied eDNA metabarcoding is increasingly being considered as a tool to inform management decisions, regulations, or policy development. Because these…”
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15
Direct PCR amplification and sequencing of specimens' DNA from preservative ethanol
Published in BioTechniques (01-03-2010)“…DNA extraction is the first step in many molecular biology protocols. However, we hypothesized that DNA from a preserved specimen can leak into its…”
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Designing and Implementing an Assay for the Detection of Rare and Divergent NRPS and PKS Clones in European, Antarctic and Cuban Soils
Published in PloS one (23-09-2015)“…The ever increasing microbial resistome means there is an urgent need for new antibiotics. Metagenomics is an underexploited tool in the field of drug…”
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An inter-laboratory study to investigate the impact of the bioinformatics component on microbiome analysis using mock communities
Published in Scientific reports (19-05-2021)“…Despite the advent of whole genome metagenomics, targeted approaches (such as 16S rRNA gene amplicon sequencing) continue to be valuable for determining the…”
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Genomic insights into specialized metabolism in the marine actinomycete Salinispora
Published in Environmental microbiology (01-09-2017)“…Summary Comparative genomics is providing new opportunities to address the diversity and distributions of genes encoding the biosynthesis of specialized…”
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Developing whole cell standards for the microbiome field
Published in Microbiome (09-08-2022)“…Background Effective standardisation of the microbiome field is essential to facilitate global translational research and increase the reproducibility of…”
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Design and applicability of DNA arrays and DNA barcodes in biodiversity monitoring
Published in BMC biology (13-06-2007)“…The rapid and accurate identification of species is a critical component of large-scale biodiversity monitoring programs. DNA arrays (micro and macro) and DNA…”
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