Search Results - "Gregor, Jamie"

High oncostatin M predicts lack of clinical remission for patients with inflammatory bowel disease on tumor necrosis factor α antagonists by Guo, Angela, Ross, Cameron, Chande, Nilesh, Gregor, Jamie, Ponich, Terry, Khanna, Reena, Sey, Michael, Beaton, Melanie, Yan, Brian, Kim, Richard B., Wilson, Aze

“…The interleukin-6 family cytokine, oncostatin-M (OSM) has been associated with response to tumor necrosis factor-α antagonists (anti-TNFs) in small cohorts of…”
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Validation of the Rockall scoring system for outcomes from non-variceal upper gastrointestinal bleeding in a Canadian setting by Enns, Robert-A, Gagnon, Yves-M, Barkun, Alan-N, Armstrong, David, Gregor, Jamie-C, Fedorak, Richard-N

“…AIM： To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS： We used data…”
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Severity of coeliac disease and clinical management study when using a non-metabolised medication: a phase I pharmacokinetic study by Chretien, Marc L, Bailey, David G, Asher, Linda, Parfitt, Jeremy, Driman, David, Gregor, Jamie, Dresser, George K

“…ObjectiveThe non-metabolised antihistamine fexofenadine has oral absorption resulting from transporter activity. Uptake by enterocyte organic anion…”
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Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe by Urquhart, Bradley L, Ware, Joseph A, Tirona, Rommel G, Ho, Richard H, Leake, Brenda F, Schwarz, Ute I, Zaher, Hani, Palandra, Joe, Gregor, Jamie C, Dresser, George K, Kim, Richard B

“…Breast cancer resistance protein (BCRP) is an efflux transporter expressed in tissues that act as barriers to drug entry. Given that single nucleotide…”
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Retrospective analysis of disease association and outcome in histologically confirmed ischemic colitis by Mosli, Mahmoud, Parfitt, Jeremy, Gregor, Jamie

“…Objective To identify risk factors, clinical features and complications in patients with ischemic colitis (IC). Methods All patients diagnosed with biopsy…”
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Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation by Thirumaran, Ranjit K., Lamba, Jatinder K., Kim, Richard B., Urquhart, Brad L., Gregor, Jamie C., Chande, Nilesh, Fan, Yiping, Qi, An, Cheng, Cheng, Thummel, Kenneth E., Hall, Stephen D., Schuetz, Erin G.

“…Vitamin D, whose levels vary seasonally with sunlight, is activated to 1α,25-dihydroxyvitamin D3 that binds the vitamin D receptor (VDR) and transcriptionally…”
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Severity of coeliac disease and clinical management study when using a CYP3A4 metabolised medication: a phase I pharmacokinetic study by Chretien, Marc L, Bailey, David G, Asher, Linda, Parfitt, Jeremy, Driman, David, Gregor, Jamie, Dresser, George K

“…ObjectiveSeverity of coeliac disease depends in part on the extent of small intestinal mucosa injury. Patients with the most abnormal pathology have loss of…”
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The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugs by Urquhart, Bradley L, Gregor, Jamie C, Chande, Nilesh, Knauer, Michael J, Tirona, Rommel G, Kim, Richard B

“…Folic acid is a vitamin essential for thymidylate and purine synthesis. The human proton-coupled folate transporter (hPCFT) has recently been identified as a…”
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Functional characterization of genetic variants in the apical sodium-dependent bile acid transporter (ASBT; SLC10A2) by Ho, Richard H, Leake, Brenda F, Urquhart, Brad L, Gregor, Jamie C, Dawson, Paul A, Kim, Richard B

“…Background and Aim:  The major transporter responsible for bile acid uptake from the intestinal lumen is the apical sodium‐dependent bile acid transporter…”
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Percutaneous endoscopic gastrostomy tube placement for end-stage palliation of malignant gastrointestinal obstructions by Teriaky, Anouar, Gregor, Jamie, Chande, Nilesh

“…Decompression of malignant gastrointestinal obstructions is an uncommon indication for percutaneous endoscopic gastrostomy (PEG) tubes. The purpose of this…”
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Transcutaneous Bowel Sonography for Inflammatory Bowel Disease Is Sensitive and Specific When Performed in a Nonexpert Low‐Volume North American Center by Sey, Michael Sai Lai, Gregor, Jamie, Chande, Nilesh, Ponich, Terry, Bhaduri, Mousumi, Lum, Andrea, Zaleski, Witek, Yan, Brian

“…Objectives Transcutaneous bowel sonography is a nonionizing imaging modality used in inflammatory bowel disease. Although available in Europe, its uptake in…”
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Follow-up of participants in the Canadian Association of Gastroenterology Scholars' Program, 2006 to 2012 by Lam, Mindy Ching Wan, Sey, Michael Sl, Gregor, Jamie, Wong, Clarence

“…The Canadian Association of Gastroenterology (CAG) Scholars' Program (previously known as the Bright Lights Course) is designed to encourage trainees to…”
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The Tricky Trachea by Chakraborty, Debarati, Shepherd, Jessica, Gregor, Jamie, Dhaliwal, Inderdeep

“…Pulmonary extra-intestinal manifestations of inflammatory bowel disease are rare, comprising 0.21% to 0.4% of the inflammatory bowel disease population. Common…”
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The Tricky Trachea: Tracheitis and Mediastinitis Treated With Infliximab and Steroids in a Patient With Ulcerative Colitis by Chakraborty, Debarati, Shepherd, Jessica, Gregor, Jamie, Dhaliwal, Inderdeep

“…Pulmonary extra-intestinal manifestations of inflammatory bowel disease are rare, comprising 0.21% to 0.4% of the inflammatory bowel disease population. Common…”
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Clinical, Endoscopic, and Radiological Effectiveness of Ustekinumab in Bio-naïve Versus Bio-experienced Patients With Crohn's Disease: Real-world Experience From a Large Canadian Center by Sedano, Rocio, Guizzetti, Leonardo, McDonald, Cassandra, Beaton, Melanie, Chande, Nilesh, Gregor, Jamie, Sey, Michael, Wilson, Aze, Jairath, Vipul

“…With the expanding therapeutic armamentarium for inflammatory bowel disease (IBD), real-world data may help inform drug positioning. We assessed clinical,…”
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Endoscopic Skipping, Stricturing, and Penetrating Complications in Crohn's Disease on Tandem Ileo-colonoscopy and Cross-sectional Imaging: A Retrospective Cohort Study by Solitano, Virginia, Vuyyuru, Sudheer Kumar, Aruljothy, Achuthan, Alkhattabi, Maan, Zou, Joshua, Beaton, Melanie, Gregor, Jamie, Kassam, Zahra, Sedano, Rocio, Marshall, Harry, Ramsewak, Darryl, Sey, Michael, Jairath, Vipul

“…Crohn's disease (CD) is characterized by discontinuous inflammation. Failure to identify skipping lesions of the terminal ileum (TI) or transmural changes can…”
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Safety of Biologic Therapy in Octogenarians and Nonagenarians With Inflammatory Bowel Disease in Ontario: A Case Series by Ayoub, Abdul, Jairath, Vipul, Aldraiweesh, Saleh, Khanna, Reena, Gregor, Jamie, Chande, Nilesh

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Self-Screening for Malnutrition Risk in Outpatient Inflammatory Bowel Disease Patients Using the Malnutrition Universal Screening Tool (MUST) by Sandhu, Amindeep, Mosli, Mahmoud, Yan, Brian, Wu, Thomas, Gregor, Jamie, Chande, Nilesh, Ponich, Terry, Beaton, Melanie, Rahman, Adam

“…Background and Aims: Malnutrition is common in patients with inflammatory bowel disease (IBD) and is associated with poor outcomes. Our aim is to determine if…”
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Wait times for diagnostic colonoscopy among outpatients with colorectal cancer: a comparison with Canadian Association of Gastroenterology targets by Sey, Michael Sai Lai, Gregor, Jamie, Adams, Paul, Khanna, Nitin, Vinden, Chris, Driman, David, Chande, Nilesh

“…Timely access to colonoscopy is a nationally recognized issue in Canada, with previous studies documenting significant wait times for a variety of indications…”
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S1485 Increasing Inpatient Endoscopy Volumes Using the Model for Continuous Improvement by Hudson, David, Hindi, Ziad, Alsager, Mohammed, Lavalle, Christopher, Alajmi, Abdulaziz, Iablokov, Vadim, Gregor, Jamie, Khanna, Nitin, Yan, Brian, Qumosani, Karim, Brahmania, Mayur

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