Search Results - "Gregianin, Lauro"
-
1
Microbiological profile and nutritional quality of a regular diet compared to a neutropenic diet in a pediatric oncology unit
Published in Pediatric blood & cancer (01-03-2018)“…It has been hypothesized that a neutropenic diet has lower microbe content. Here, the microbiological and nutritional contents of regular and neutropenic diets…”
Get full text
Journal Article -
2
The effect of hospital care volume on overall survival of children with cancer in Southern Brazil
Published in Pediatric blood & cancer (01-03-2021)“…Purpose The purpose of this study was to analyze the effect of hospital care volume on the overall survival of children with cancer in Southern Brazil…”
Get full text
Journal Article -
3
Risk factors associated with the development of oral mucositis in pediatric oncology patients: Systematic review and meta‐analysis
Published in Oral diseases (01-05-2022)“…Objectives Oral mucositis (OM) is an acute toxicity related to cancer treatment. This systematic review aimed to identify potential risk factors associated…”
Get full text
Journal Article -
4
Population Pharmacokinetic Model of Methotrexate in Brazilian Pediatric Patients with Acute Lymphoblastic Leukemia
Published in Pharmaceutical research (01-07-2023)“…Objectives Methotrexate (MTX) is subject to therapeutic drug monitoring because of its high pharmacokinetic variability and safety risk outside the therapeutic…”
Get full text
Journal Article -
5
Incidence and risk factors for oral mucositis in pediatric patients receiving chemotherapy
Published in Supportive care in cancer (01-11-2021)“…Purpose To investigate the incidence and risk factors for oral mucositis (OM) in patients with childhood cancer undergoing chemotherapy. Methods Eight hundred…”
Get full text
Journal Article -
6
Anticipating Leucovorin Rescue Therapy in Patients with Osteosarcoma through Methotrexate Population Pharmacokinetic Model
Published in Pharmaceutics (06-09-2024)“…Methotrexate (MTX), which presents high inter-individual variability, is part of the Brazilian Osteosarcoma Treatment Group (BOTG) protocol. This work aimed to…”
Get full text
Journal Article -
7
Illness perceptions in childhood cancer survivor and caregivers’ dyads
Published in Clinical child psychology and psychiatry (01-07-2022)“…Surviving childhood cancer is a difficult experience for children and their caregivers, it can produce long-term emotional distress. Illness perceptions refer…”
Get full text
Journal Article -
8
Histone Methyltransferases G9a/Ehmt2 and GLP/Ehmt1 Are Associated with Cell Viability and Poorer Prognosis in Neuroblastoma and Ewing Sarcoma
Published in International journal of molecular sciences (17-10-2023)“…Changes in epigenetic programming have been proposed as being key events in the initiation and progression of childhood cancers. HMT euchromatic histone lysine…”
Get full text
Journal Article -
9
Epidermal Growth Factor Receptor Regulation of Ewing Sarcoma Cell Function
Published in Oncology (01-01-2018)“…Ewing sarcoma (ES) is a type of childhood cancer probably arising from stem mesenchymal or neural crest cells. The epidermal growth factor receptor (EGFR) acts…”
Get more information
Journal Article -
10
BDNF/TrkB Signaling as a Potential Novel Target in Pediatric Brain Tumors: Anticancer Activity of Selective TrkB Inhibition in Medulloblastoma Cells
Published in Journal of molecular neuroscience (01-07-2016)“…Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Deregulation of brain-derived neurotrophic factor (BDNF)/tropomyosin-related kinase B…”
Get full text
Journal Article -
11
New photobiomodulation protocol prevents oral mucositis in hematopoietic stem cell transplantation recipients—a retrospective study
Published in Lasers in medical science (01-12-2017)“…Oral mucositis (OM) is an adverse side effect among hematopoietic stem cell transplantation (HSCT) recipients. The objective of this retrospective study was to…”
Get full text
Journal Article -
12
Cancer Stem Cells and Chemoresistance in Ewing Sarcoma
Published in Current stem cell research & therapy (01-01-2023)“…Resistance to chemotherapy poses a major challenge for cancer treatment. Reactivating a stem cell program resembling that seen in embryonic development can…”
Get more information
Journal Article -
13
Combined Treatments with a Retinoid Receptor Agonist and Epigenetic Modulators in Human Neuroblastoma Cells
Published in Molecular neurobiology (01-12-2017)“…Neuroblastoma (NB) is the most common extracranial solid childhood tumor accounting for around 15% of pediatric cancer deaths and most probably originates from…”
Get full text
Journal Article -
14
Stemness and Cell Cycle Regulators and Their Modulation by Retinoic Acid in Ewing Sarcoma
Published in Current issues in molecular biology (01-05-2024)“…Retinoic acid (RA) regulates stemness and differentiation in human embryonic stem cells (ESCs). Ewing sarcoma (ES) is a pediatric tumor that may arise from the…”
Get full text
Journal Article -
15
What is the impact of local control in Ewing sarcoma: analysis of the first Brazilian collaborative study group - EWING1
Published in BMC cancer (15-06-2017)“…Relapse in localized Ewing sarcoma patients has been a matter of concern regarding poor prognosis. Therefore, we investigated the impact of local control…”
Get full text
Journal Article -
16
Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma
Published in Oncotarget (07-06-2016)“…Ewing sarcoma (ES) is a highly aggressive pediatric cancer that may arise from neuronal precursors. Neurotrophins stimulate neuronal devlopment and plasticity…”
Get full text
Journal Article -
17
The use of high-frequency audiometry increases the diagnosis of asymptomatic hearing loss in pediatric patients treated with cisplatin-based chemotherapy
Published in Pediatric blood & cancer (01-03-2013)“…Background Cisplatin may cause permanent cochlear damage by changing cochlear frequency selectivity and can lead to irreversible sensorineural hearing loss…”
Get full text
Journal Article -
18
Carboplatin in the treatment of Ewing sarcoma: Results of the first Brazilian Collaborative Study Group for Ewing Sarcoma Family Tumors-EWING1
Published in Pediatric blood & cancer (01-10-2015)“…Background Large cooperative group studies have shown the efficacy of risk‐adapted treatment for Ewing sarcoma. However, validation and local adaptation by…”
Get full text
Journal Article -
19
Trk Inhibition Reduces Tumorsphere Formation and Changes Expression of Stemness Markers in SK-ES-1 Ewing Sarcoma Cells
Published in Revista Brasileira de Cancerologia (05-01-2024)“…Introduction: Ewing sarcoma (ES) is a highly aggressive type of childhood cancer characterized by a chromosomal translocation resulting in fusions between the…”
Get full text
Journal Article -
20
Investigation of oral and general health status and IL-1β gene polymorphism as risk factors for oral mucositis in hematopoietic stem cell transplantation patients
Published in Brazilian oral research (2022)“…The aim of the present study was to analyze the relationship of OM with possible risk factors such as oral health condition, immunological status and IL-1β…”
Get full text
Journal Article