Surgical versus conservative treatment of unilateral subaxial non-subluxed facet fractures: A systematic review and meta-analysis

•Surgical intervention has lower treatment failure rates in treating USNSFF.•Neurologic deficit is prognostic of conservative treatment failure.•Ligamentous involvement is prognostic of conservative treatment failure.•Conservative management is generally effective in the absence of severe pathology....

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Published in:Clinical neurology and neurosurgery Vol. 199; p. 106280
Main Authors: Larkin, Collin J., Abecassis, Zachary A., Yerneni, Ketan, Nistal, Dominic A., Karras, Constantine L., Greg Frankel, H., Ayer, Amit, Dahdaleh, Nader S.
Format: Journal Article
Language:English
Published: Netherlands Elsevier B.V 01-12-2020
Elsevier Limited
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Summary:•Surgical intervention has lower treatment failure rates in treating USNSFF.•Neurologic deficit is prognostic of conservative treatment failure.•Ligamentous involvement is prognostic of conservative treatment failure.•Conservative management is generally effective in the absence of severe pathology. Unilateral subaxial non-subluxed facet fractures (USNSFF) are a pathology seen in traumatic events such as motor vehicle accidents. Management involves either rigid collar bracing or surgical intervention. There currently is no consensus on the treatment of these injuries; this review aims to examine the extant data for recommendations as to which treatment is more effective. MEDLINE, Scopus, and the Cochrane trial register were all searched on January 16, 2020, comparing outcomes for surgical and conservative therapy for USNSFF. The meta-analysis examined rates of treatment failure (need for subsequent operative management) in conservative versus surgical management. The meta-analysis was performed using a random effects model, with visualization in forest and L'Abbé plots. We identified six retrospective studies describing 270 patients, with three studies describing 137 patients used in the meta-analysis. Overall, a surgical success rate of 97.7 % and a non-operative success rate of 79.7 % was observed. A random effects model risk ratio of 1.66 (95 % CI: 0.61–4.52) was obtained, suggesting efficacy of surgical management over conservative management. The need for surgical intervention subsequent to initial management in the treatment of USNSFF was found to be lower in surgical treatment in contrast to conservative management. However, the studies that were included in the meta-analysis had patient cohorts with much higher rates of neurological deficit and ligamentous injury on presentation, indicating that these may be prognostic indicators of conservative management failure. Furthermore, those that did fail conservative management did not develop severely debilitating conditions. Accordingly, conservative treatment is generally sufficient as a first step in a majority of cases of USNSFF lacking neurological deficit or ligamentous involvement.
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ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2020.106280