Search Results - "Greff, Z"

Novel, selective CDK9 inhibitors for the treatment of HIV infection by Németh, G, Varga, Z, Greff, Z, Bencze, G, Sipos, A, Szántai-Kis, C, Baska, F, Gyuris, A, Kelemenics, K, Szathmáry, Z, Minárovits, J, Kéri, G, Orfi, L

“…Cyclin Dependent Kinases (CDKs) are important regulators of cell cycle and gene expression. Since an up-to-date review about the pharmacological inhibitors of…”
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Developing FGFR4 inhibitors as potential anti-cancer agents via in silico design, supported by in vitro and cell-based testing by Ho, H K, Németh, G, Ng, Y R, Pang, E, Szántai-Kis, C, Zsákai, L, Breza, N, Greff, Z, Horváth, Z, Pató, J, Szabadkai, I, Szokol, B, Baska, F, Őrfî, L, Ullrich, A, Kéri, G, Chua, B T

“…Fibroblast growth factor receptor-4 (FGFR4) is a tyrosine kinase with a range of important physiological functions. However, it is also frequently mutated in…”
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Signalling inhibitors against Mycobacterium tuberculosis--early days of a new therapeutic concept in tuberculosis by Hegymegi-Barakonyi, B, Székely, R, Varga, Z, Kiss, R, Borbély, G, Németh, G, Bánhegyi, P, Pató, J, Greff, Z, Horváth, Z, Mészáros, G, Marosfalvi, J, Erōs, D, Szántai-Kis, C, Breza, N, Garavaglia, S, Perozzi, S, Rizzi, M, Hafenbradl, D, Ko, M, Av-Gay, Y, Klebl, B M, Orfi, L, Kéri, G

“…Tuberculosis causes nearly two million deaths per year world-wide. In addition multidrug-resistant mycobacterial strains rapidly emerge so novel therapeutic…”
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Cellular targets of gefitinib by BREHMER, Dirk, GREFF, Zoltan, WISSING, Josef, DAUB, Henrik, GODL, Klaus, BLENCKE, Stephanie, KURTENBACH, Alexander, WEBER, Martina, MÜLLER, Stefan, KLEBL, Bert, COTTEN, Matt, KERI, György

“…Targeted inhibition of protein kinases with small molecule drugs has evolved into a viable approach for anticancer therapy. However, the true selectivity of…”
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The First Lateral Functionalization of Calix[4]arenes by a Homologous Anionic Ortho-Fries Rearrangement by Middel, Oskar, Greff, Zoltan, Taylor, Nick J, Verboom, Willem, Reinhoudt, David N, Snieckus, Victor

“…Treatment of calix[4]arene bis-O-carbamates 4a,b−6a,b with LDA in THF results in the regio- and stereoselective introduction of both axial and equatorial…”
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Drug discovery in the kinase inhibitory field using the Nested Chemical Library technology by Kéri, György, Székelyhidi, Zsolt, Bánhegyi, Péter, Varga, Zoltán, Hegymegi-Barakonyi, Bálint, Szántai-Kis, Csaba, Hafenbradl, Doris, Klebl, Bert, Muller, Gerhard, Ullrich, Axel, Erös, Dániel, Horváth, Zoltán, Greff, Zoltán, Marosfalvi, Jenö, Pató, János, Szabadkai, István, Szilágyi, Ildikó, Szegedi, Zsolt, Varga, István, Wáczek, Frigyes, Orfi, László

“…Kinase inhibitors are at the forefront of modern drug research, where mostly three technologies are used for hit-and-lead finding: high throughput screening of…”
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Characterization of a Conserved Structural Determinant Controlling Protein Kinase Sensitivity to Selective Inhibitors by Blencke, Stephanie, Zech, Birgit, Engkvist, Ola, Greff, Zoltán, Őrfi, László, Horváth, Zoltán, Kéri, György, Ullrich, Axel, Daub, Henrik

“…Some protein kinases are known to acquire resistance to selective small molecule inhibitors upon mutation of a conserved threonine at the ATP binding site to a…”
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