Search Results - "Greenspan, Ralph"
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Fast near-whole-brain imaging in adult Drosophila during responses to stimuli and behavior
Published in PLoS biology (15-02-2019)“…Whole-brain recordings give us a global perspective of the brain in action. In this study, we describe a method using light field microscopy to record…”
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The Brain Activity Map Project and the Challenge of Functional Connectomics
Published in Neuron (Cambridge, Mass.) (21-06-2012)“…The function of neural circuits is an emergent property that arises from the coordinated activity of large numbers of neurons. To capture this, we propose…”
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Differential mechanisms underlie trace and delay conditioning in Drosophila
Published in Nature (London) (10-03-2022)“…Two forms of associative learning—delay conditioning and trace conditioning—have been widely investigated in humans and higher-order mammals 1 . In delay…”
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Memoir of the early years of the CSHL summer Drosophila neurobiology course: 1984-1985
Published in Journal of neurogenetics (02-09-2024)Get full text
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Connectomics-Based Analysis of Information Flow in the Drosophila Brain
Published in Current biology (18-05-2015)“…Understanding the overall patterns of information flow within the brain has become a major goal of neuroscience. In the current study, we produced a first…”
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Flyception: imaging brain activity in freely walking fruit flies
Published in Nature methods (01-07-2016)“…Flyception is a tracking and imaging system that enables the monitoring of brain activity in freely walking fruit flies, making the analysis of calcium…”
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Learning about quantitative genetics from Marla Sokolowski
Published in Journal of neurogenetics (03-07-2021)“…Marla Sokolowski is a true pioneer in behavioral genetics, having made the first molecular delineation of a naturally occurring behavioral polymorphism in her…”
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Serotonin and neuropeptide F have opposite modulatory effects on fly aggression
Published in Nature genetics (01-05-2007)“…Both serotonin (5-HT) and neuropeptide Y have been shown to affect a variety of mammalian behaviors, including aggression. Here we show in Drosophila…”
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Publisher Correction: Differential mechanisms underlie trace and delay conditioning in Drosophila
Published in Nature (London) (07-04-2022)Get full text
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A Comprehensive Wiring Diagram of the Protocerebral Bridge for Visual Information Processing in the Drosophila Brain
Published in Cell reports (Cambridge) (30-05-2013)“…How the brain perceives sensory information and generates meaningful behavior depends critically on its underlying circuitry. The protocerebral bridge (PB) is…”
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The Brain Activity Map
Published in Science (American Association for the Advancement of Science) (15-03-2013)“…Researchers propose building technologies to enable comprehensive mapping of neural circuit activity to understand brain function and disease. Neuroscientists…”
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Activation of EGFR and ERK by rhomboid signaling regulates the consolidation and maintenance of sleep in Drosophila
Published in Nature neuroscience (01-09-2007)“…Epidermal growth factor receptor (EGFR) signaling in the mammalian hypothalamus is important in the circadian regulation of activity. We have examined the role…”
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Imaging brain activity during complex social behaviors in Drosophila with Flyception2
Published in Nature communications (30-01-2020)“…Optical in vivo recordings from freely walking Drosophila are currently possible only for limited behaviors. Here, we expand the range of accessible behaviors…”
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Valence opponency in peripheral olfactory processing
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2022)“…A hallmark of complex sensory systems is the organization of neurons into functionally meaningful maps, which allow for comparison and contrast of parallel…”
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15
Molecular analysis of flies selected for aggressive behavior
Published in Nature genetics (01-09-2006)“…Aggressive behavior is pervasive throughout the animal kingdom, and yet very little is known about its molecular underpinnings. To address this problem, we…”
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Deep(er) Learning
Published in The Journal of neuroscience (22-08-2018)“…Animals successfully thrive in noisy environments with finite resources. The necessity to function with resource constraints has led evolution to design animal…”
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The Drosophila foraging gene mediates adult plasticity and gene-environment interactions in behaviour, metabolites, and gene expression in response to food deprivation
Published in PLoS genetics (01-08-2009)“…Nutrition is known to interact with genotype in human metabolic syndromes, obesity, and diabetes, and also in Drosophila metabolism. Plasticity in metabolic…”
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Dopaminergic Modulation of Arousal in Drosophila
Published in Current biology (12-07-2005)“…Background: Arousal levels in the brain set thresholds for behavior, from simple to complex. The mechanistic underpinnings of the various phenomena comprising…”
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Jellyfish nervous systems
Published in Current biology (22-07-2013)“…What are jellyfish? The term jellyfish generally refers to the umbrella-shaped gelatinous zooplanktons that belong to Scyphozoa (true jellyfish), Staurozoa…”
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The genome of the jellyfish Aurelia and the evolution of animal complexity
Published in Nature ecology & evolution (01-01-2019)“…We present the genome of the moon jellyfish Aurelia , a genome from a cnidarian with a medusa life stage. Our analyses suggest that gene gain and loss in…”
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