Search Results - "Greenspan, R J"

Correlates of Sleep and Waking in Drosophila melanogaster by Shaw, Paul J., Cirelli, Chiara, Greenspan, Ralph J., Tononi, Giulio

“…Drosophila exhibits a circadian rest-activity cycle, but it is not known whether fly rest constitutes sleep or is mere inactivity. It is shown here that, like…”
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Natural behavior polymorphism due to a cGMP-dependent protein kinase of Drosophila by Osborne, K.A. (New York University, New York, NY.), Robichon, A, Burgess, E, Butland, S, Shaw, R.A, Coulthard, A, Pereira, H.S, Greenspan, R.J, Sokolowski, M.B

“…Naturally occuring polymorphisms in behavior are dlfficult to map genetically and thus are refractory to molecular characterization. An exception is the…”
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Courtship in Drosophila by Greenspan, R J, Ferveur, J F

“…Courtship is a complex behavior in Drosophila that recruits a wide range of genes for its realization, including those concerning sex determination, ion…”
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Uncoupling of Brain Activity from Movement Defines Arousal States in Drosophila by van Swinderen, B, Nitz, D.A, Greenspan, R.J

“…Background: An animal's state of arousal is fundamental to all of its behavior. Arousal is generally ascertained by measures of movement complemented by brain…”
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‘Am not I a fly like thee?’ From genes in fruit flies to behavior in humans by Greenspan, Ralph J., Dierick, Herman A.

“…The fruit fly Drosophila melanogaster has provided insight into the role of genes in behavior, some of which have relevant implications for humans. Mutants…”
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Conservation of the behavioral and transcriptional response to social experience among Drosophilids by Shultzaberger, R. K., Johnson, S. J., Wagner, J., Ha, K., Markow, T. A., Greenspan, R. J.

“…While social experience has been shown to significantly alter behaviors in a wide range of species, comparative studies that uniformly measure the impact of a…”
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Genetic feminization of pheromones and its behavioral consequences in Drosophila males by Ferveur, J.F. (Universite Paris-Sud, Orsay, France.), Savarit, F, O'Kane, C.J, Sureau, G, Greenspan, R.J, Jallon, J.M

“…Pheromones are intraspecific chemical signals important for mate attraction and discrimination. In the fruit fly Drosophila melanogaster, hydrocarbons on the…”
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Selection, gene interaction, and flexible gene networks by Greenspan, R J

“…Recent results from a variety of different kinds of experiments, mainly using behavior as an assay, and ranging from laboratory selection experiments to gene…”
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Genetic Feminization of Brain Structures and Changed Sexual Orientation in Male Drosophila by Ferveur, Jean-François, Störtkuhl, Klemens F., Stocker, Reinhard F., Greenspan, Ralph J.

“…The neural basis of sexual orientation in Drosophila was studied by the production of males with regionally feminized brains. Such flies express the female…”
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Inhibition of calcium/calmodulin-dependent protein kinase in Drosophila disrupts behavioral plasticity by Griffith, L C, Verselis, L M, Aitken, K M, Kyriacou, C P, Danho, W, Greenspan, R J

“…One of the major mediators of calcium action in neurons is the multifunctional calcium/calmodulin-dependent protein kinase (CaM kinase), an enzyme with the…”
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Electrophysiological Correlates of Rest and Activity in Drosophila melanogaster by Nitz, Douglas A, van Swinderen, Bruno, Tononi, Giulio, Greenspan, Ralph J

“…Extended periods of rest in Drosophila melanogaster resemble mammalian sleep states in that they are characterized by heightened arousal thresholds and…”
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Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development by DEL AMO, F. F, SMITH, D. E, SWIATEK, P. J, GENDRON-MAGUIRE, M, GREENSPAN, R. J, MCMAHON, A. P, GRIDLEY, T

“…The Notch gene of Drosophila encodes a large transmembrane protein involved in cell-cell interactions and cell fate decisions in the Drosophila embryo. To…”
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Calcium/calmodulin-dependent protein kinase II and potassium channel subunit eag similarly affect plasticity in Drosophila by Griffith, L.C, Wang, J, Zhong, Y, Wu, C.F, Greenspan, R.J

“…Similar defects in both synaptic transmission and associative learning are produced in Drosophila melanogaster by inhibition of calcium/calmodulin-dependent…”
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Salience modulates 20-30 Hz brain activity in Drosophila by Greenspan, Ralph J, van Swinderen, Bruno

“…Fruit flies selectively orient toward the visual stimuli that are most salient in their environment. We recorded local field potentials (LFPs) from the brains…”
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Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait by White, Kevin P, Greenspan, Ralph J, Toma, Daniel P, Hirsch, Jerry

“…Identifying the genes involved in polygenic traits has been difficult. In the 1950s and 1960s, laboratory selection experiments for extreme geotaxic behavior…”
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Neurohormonal and neuromodulatory control of sleep in Drosophila by Foltenyi, K, Andretic, R, Newport, J W, Greenspan, R J

“…The fruit fly Drosophila melanogaster has emerged in recent years as a tractable system for studying sleep. The sleep-wake dichotomy represents one of the…”
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Excitatory and Inhibitory Switches for Courtship in the Brain of Drosophila melanogaster by Broughton, Susan J, Kitamoto, Toshihiro, Greenspan, Ralph J

“…Background: Courtship is the best-studied behavior in Drosophila melanogaster, and work on its anatomical basis has concentrated mainly on the functional…”
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Cognitive consonance: complex brain functions in the fruit fly and its relatives by Greenspan, Ralph J., van Swinderen, Bruno

“…The fruit fly, Drosophila melanogaster, has become a model for the study of a growing number of human characteristics because of the power of its genetics…”
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The diversity of calcium/calmodulin-dependent protein kinase II isoforms in Drosophila is generated by alternative splicing of a single gene by Griffith, L C, Greenspan, R J

“…To investigate the mechanism by which Drosophila generates multiple calcium/calmodulin-dependent protein kinase II (CaM kinase) subunits, CaM kinase cDNAs were…”
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Conversion of Placental Alkaline Phosphatase from a Phosphatidylinositol-glycan-anchored Protein to an Integral Transmembrane Protein by Berger, Joel, Micanovic, Radmila, Greenspan, Ralph J., Udenfriend, Sidney

“…Placental alkaline phosphatase (PLAP) is normally anchored to the plasma membrane of cells by a phosphatidylinositol-glycan anchor after removal of a…”
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