Search Results - "Greenhalgh, C"

Machine learning-guided acyl-ACP reductase engineering for improved in vivo fatty alcohol production by Greenhalgh, Jonathan C., Fahlberg, Sarah A., Pfleger, Brian F., Romero, Philip A.

“…Alcohol-forming fatty acyl reductases (FARs) catalyze the reduction of thioesters to alcohols and are key enzymes for microbial production of fatty alcohols…”
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A systematic review and meta-analysis of disease burden of healthcare-associated infections in China: an economic burden perspective from general hospitals by Liu, X., Spencer, A., Long, Y., Greenhalgh, C., Steeg, S., Verma, A.

“…Healthcare-associated infections (HAIs) are a global public health issue. However, the economic burden attributable to HAIs at a national level is unknown in…”
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A systematic review and meta-analysis of risk factors associated with healthcare-associated infections among hospitalized patients in Chinese general hospitals from 2001 to2022 by Liu, X., Long, Y., Greenhalgh, C., Steeg, S., Wilkinson, J., Li, H., Verma, A., Spencer, A.

“…Healthcare-associated infections (HAIs) are a serious global public health issue. However, a comprehensive analysis of risk factors for HAIs has yet been…”
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Modified realist evaluation of a complex, multi-centred, multi-intervention programme by Greenhalgh, C, Williams, G, Harrison, A, Garrow, A, Mitchell, S, Verma, A

“…Abstract Well North was a complex, multi-intervention health improvement programme spanning 10 sites across the North of England. The aim was to address…”
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Transient Metastable Behavior Caused by Magnesium-Doped Zinc Oxide Emitters in CdSeTe/CdTe Solar Cells by Togay, Mustafa, Greenhalgh, Rachael C., Fiducia, Thomas A., Shimpi, Tushar, Sampath, Walajabad, Barth, Kurt L., Walls, John M., Bowers, Jake W.

“…Metastable behavior in highly efficient MZO/CdSeTe/CdTe solar cells has been reported previously. Different preconditioning procedures have been studied that…”
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Precision computerised cognitive behavioural therapy (cCBT) for adolescents with depression: a pilot and feasibility randomised controlled trial protocol for SPARX-UK by Khan, K, Hall, C L, Babbage, C, Dodzo, S, Greenhalgh, C, Lucassen, M, Merry, S, Sayal, K, Sprange, K, Stasiak, K, Tench, C R, Townsend, E, Stallard, P, Hollis, C

“…A serious game called SPARX (Smart, Positive, Active, Realistic, X-factor thoughts), originally developed in New Zealand and incorporating cognitive…”
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Gigantism in mice lacking suppressor of cytokine signalling-2 by Alexander, Warren S, Metcalf, Donald, Greenhalgh, Christopher J, Viney, Elizabeth, Willson, Tracy A, Starr, Robyn, Nicola, Nicos A, Hilton, Douglas J

“…Suppressor of cytokine signalling-2 (SOCS-2) is a member of the suppressor of cytokine signalling family, a group of related proteins implicated in the…”
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Sedation challenge by Greenhalgh, C

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Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon by RIGBY, R. J, SIMMONS, J. G, GREENHALGH, C. J, ALEXANDER, W. S, LUND, P. K

“…Intestinal injury or chronic inflammation induce cytokines that promote crypt regeneration and mucosal repair. If excessive or prolonged, such mechanisms may…”
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Virtual reality simulation of surgery with haptic feedback based on the boundary element method by Wang, P., Becker, A.A., Jones, I.A., Glover, A.T., Benford, S.D., Greenhalgh, C.M., Vloeberghs, M.

“…A virtual reality real-time simulation of surgical operations has been developed using the boundary element (BE) method. Other numerical techniques and related…”
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SOCS3 negatively regulates IL-6 signaling in vivo by Alexander, Warren S, Croker, Ben A, Krebs, Danielle L, Zhang, Jian-Guo, Wormald, Sam, Willson, Tracy A, Stanley, Edouard G, Robb, Lorraine, Greenhalgh, Christopher J, Förster, Irmgard, Clausen, Björn E, Nicola, Nicos A, Metcalf, Donald, Hilton, Douglas J, Roberts, Andrew W

“…Members of the suppressor of cytokine signaling (SOCS) family are potentially key physiological negative regulators of interleukin-6 (IL-6) signaling. To…”
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Yeast surface display-based identification of ACE2 mutations that modulate SARS-CoV-2 spike binding across multiple mammalian species by Heinzelman, Pete, Greenhalgh, Jonathan C, Romero, Philip A

“…Abstract Understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with different mammalian angiotensin-converting enzyme II…”
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A virtual reality surgery simulation of cutting and retraction in neurosurgery with force-feedback by Wang, P., Becker, A.A., Jones, I.A., Glover, A.T., Benford, S.D., Greenhalgh, C.M., Vloeberghs, M.

“…A virtual-reality surgical simulator aimed at neurosurgery is presented. The simulator utilises boundary element (BE) technology to develop real-time realistic…”
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Coping with uncertainty in a location-based game by Benford, S., Anastasi, R., Flintham, M., Greenhalgh, C., Tandavanitj, N., Adams, M., Row-Farr, J.

“…With location-based games, how you manage uncertainty can make the difference between fun and fiasco. Game designers should know what uncertainties to hide and…”
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A response to ‘Conscious sedation for dental treatment’[1] by Greenhalgh, C.

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Negative regulation of cytokine signaling by Greenhalgh, Christopher J., Hilton, Douglas J.

“…Cytokines use complex signaling cascades to elicit their biological effects, many of which involve phosphorylation as a mechanism of activation. Rapid and…”
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In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3 by Callejo, Gerard, Pattison, Luke A., Greenhalgh, Jack C., Chakrabarti, Sampurna, Andreopoulou, Evangelia, Hockley, James R.F., Smith, Ewan St. John, Rahman, Taufiq

“…[Display omitted] Acid-sensing ion channels (ASICs) are voltage-independent cation channels that detect decreases in extracellular pH. Dysregulation of ASICs…”
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Theoretical model for the thermal conductivity of a packed bed of solid spheroids in the presence of a static gas, with no adjustable parameters except at low pressure and temperature by Slavin, A.J., Arcas, V., Greenhalgh, C.A., Irvine, E.R., Marshall, D.B.

“…Many analytical models exist for the thermal conductivity of packed pebble beds in a static gas, but all require adjustable parameters to give good fits to…”
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Direct Integration of Perovskite Solar Cells with Carbon Fiber Substrates by Game, Onkar S., Thornber, Timothy, Cepero‐Mejías, Fernando, Infante‐Ortega, Luis C., Togay, Mustafa, Cassella, Elena J., Kilbride, Rachel C., Gordon, Robert H., Mullin, Nic, Greenhalgh, Rachael C., Isherwood, Patrick J. M., Walls, J. Michael, Fairclough, J. Patrick A., Lidzey, David G.

“…Integrating photovoltaic devices onto the surface of carbon‐fiber‐reinforced polymer substrates should create materials with high mechanical strength that are…”
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The Mechanical Response and Tolerance of the Anteriorly-Tilted Human Pelvis Under Vertical Loading by Salzar, R. S., Spratley, E. M., Henderson, K. A., Greenhalgh, P. C., Zhang, J. Z., Perry, B. J., McMahon, J. A.

“…Military vehicle underbody blast (UBB) is the cause of many serious injuries in theatre today; however, the effects of these chaotic events on the human body…”
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