Search Results - "Greene, N D"

Editorial: Maternal-foetal crosstalk impacts on offspring development by Ybot-Gonzalez, P, Greene, N D E, Copp, A J, Henderson, D J, Massa, V

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Overcoming analytical and preanalytical challenges associated with extragenital home collected STI specimens by Hockman, B E, Qi, M, Rotblatt, H, Borenstein, L, Flynn, R A, Muldrow, R A, Rajagopalan, S, Greene, D N

“…Home sample collection for sexually transmitted infection (STI) screening options can improve access to sexual healthcare across communities. For (CT) and…”
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A targeted sequencing panel identifies rare damaging variants in multiple genes in the cranial neural tube defect, anencephaly by Ishida, M., Cullup, T., Boustred, C., James, C., Docker, J., English, C., Lench, N., Copp, A.J., Moore, G.E., Greene, N.D.E., Stanier, P.

“…Neural tube defects (NTDs) affecting the brain (anencephaly) are lethal before or at birth, whereas lower spinal defects (spina bifida) may lead to lifelong…”
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A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development by Christensen, K E, Deng, L, Leung, K Y, Arning, E, Bottiglieri, T, Malysheva, O V, Caudill, M A, Krupenko, N I, Greene, N D, Jerome-Majewska, L, MacKenzie, R E, Rozen, R

“…Genetic variants in one-carbon folate metabolism have been identified as risk factors for disease because they may impair the production or use of one-carbon…”
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Genetically determined folate deficiency is associated with abnormal hepatic folate profiles in the spontaneously hypertensive rat by Pravenec, M, Leung, K Y, Zídek, V, Mlejnek, P, Šimáková, M, Šilhavý, J, Kožich, V, Greene, N D E

“…Increased levels of plasma cysteine are associated with obesity and metabolic disturbances. Our recent genetic analyses in spontaneously hypertensive rats…”
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In response to the Letter to the Editor by Romach et al. re our publication “Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels” by Mohan, H., Guzman Lenis, M., Laurette, E.Y., Tejada, O., Sanghvi, T., Leung, K.-Y., Cahill, L.S., Sled, J.G., Delgado-Olguín, P., Greene, N.D.E., Copp, A.J., Serghides, L.

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Evaluation of folate metabolism gene polymorphisms as risk factors for open and closed neural tube defects by Doudney, K., Grinham, J., Whittaker, J., Lynch, S.A., Thompson, D., Moore, G.E., Copp, A.J., Greene, N.D.E., Stanier, P.

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B-203 Development and Validation of an LC/MS/MS Method to Quantify Creatinine in Dried Blood Spots by Torres, C, Muldrow, R, Greene, D N

“…Abstract Background Health disparities in diagnosis and treatment of chronic kidney disease (CKD) are apparent with Black, Brown, and socially disadvantaged…”
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OC126: The PONTI (Prevention of neural tube defects by inositol) clinical trial by Chitty, L. S., Greene, N. D. E., Burren, K., Hesketh, T., Copp, A.

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A-341 Development and Validation of an ICP-MS Method to Quantify Lead in Dried Blood Spots by Muldrow, R A, Torres, C, Kaiwusaier, K, Martir, S, Greene, D N

“…Abstract Introduction The CDC estimates that ∼500 000 children in the US between ages 1–5 have unsafe blood lead concentrations (> 3.5 ug/dL). Lead toxicity…”
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A-253 Overcoming Pre-Analytical and Analytical Challenges Associated with Home Collected STI Specimens by Hockman, B, Qi, M, Rotblatt, H, Borenstein, L, Rajagopalan, S, Greene, D N

“…Abstract Introduction Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are common sexually transmitted infections (STIs) that are often asymptomatic,…”
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A-056 Data Driven Approach to Ensure Accurate Total Testosterone Results in Consumer Initiated, Home-collected Capillary Samples by Naranjo, A R, Carter, C, Chen, J, Hamdan, A, Krasowski, M D, O’Connor, K, Greene, D N

“…Abstract Background Home-collected direct access testing (DAT) has become increasingly attractive as telehealth utilization advances. With DAT, consumers…”
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A-234 Self-collected Vaginal Swabs for High-risk HPV Testing in the us: Validation of Pre-analytical Variables by Qi, M, Duque, A J, Lorey, T S, Naranjo, A, Rummel, M, Schapiro, J M, Suh-Burgmann, B J, Greene, D N

“…Abstract Introduction Several clinical trials have illustrated that primary HPV screening with unsupervised self-collected vaginal swabs is clinically…”
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Identification of a Transactivation Motif in the CLN3 Protein by Leung, K. Y., Greene, N. D. E., Munroe, P. B., Mole, S. E.

“…A transactivation motif has been identified in the neurodegenerative disease protein, CLN3. The C‐terminal domain (residues 394‐438) of CLN3 can function as a…”
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Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse by LEUNG, Kit-Yi, DE CASTRO, Sandra C. P, SAVERY, Dawn, COPP, Andrew J, GREENE, Nicholas D. E

“…Closure of the neural tube during embryogenesis is a crucial step in development of the central nervous system. Failure of this process results in neural tube…”
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Immunocytochemical Localization of IgG on Adult Schistosoma mansoni Tegumental Surfaces by Kemp, Walter M., Damian, Raymond T., Greene, Nathan D.

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The occurrence of baboon-type IgG subclass antigenic determinants within the order primates by Damian, R T, Luker, M F, Greene, N D, Kalter, S S

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Bleomycin-induced lung injury in baboons: alteration of cells and immunoglobulins recoverable by bronchoalveolar lavage by McCullough, B, Schneider, S, Greene, N D, Johanson, Jr, W G

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Abnormal folate metabolism in foetuses affected by neural tube defects by Dunlevy, Louisa P. E., Chitty, Lyn S., Burren, Katie A., Doudney, Kit, Stojilkovic-Mikic, Taita, Stanier, Philip, Scott, Rosemary, Copp, Andrew J., Greene, Nicholas D. E.

“…Folic acid supplementation can prevent many cases of neural tube defects (NTDs), whereas suboptimal maternal folate status is a risk factor, suggesting that…”
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Response of baboon peripheral blood lymphocytes to phytohemagglutinin: time-course and dose-response relationships by Greene, N D, Schneider, S L, Meltz, M L

“…Optimal conditions for studying phytohemagglutinin(PHA)-induced transformation of baboon peripheral blood lymphocytes were determined. Maximal stimulation, as…”
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