Search Results - "Greenaway, Frederick T"
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MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A
Published in Journal of advanced research (01-02-2022)“…Schematic illustration of the miR-4521-FAM129A axis in HCC malignancy. FAM129A negatively correlates with miR-4521, leading to suppressed migration and…”
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A novel ETV6-miR-429-CRKL regulatory circuitry contributes to aggressiveness of hepatocellular carcinoma
Published in Journal of experimental & clinical cancer research (23-04-2020)“…Tumor metastasis is one of the main causes of the high mortality of hepatocellular carcinoma (HCC). E-Twenty Six variant gene 6 (ETV6) is a strong…”
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33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways
Published in Journal of advanced research (01-05-2021)“…[Display omitted] As a member of annexin family proteins, annexin A3 (ANXA3) has 36-kDa and 33-kDa isoforms. ANXA3 plays crucial roles in the tumorigenesis,…”
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Correction to: A novel ETV6-miR-429-CRKL regulatory circuitry contributes to aggressiveness of hepatocellular carcinoma
Published in Journal of experimental & clinical cancer research (17-02-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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5
Identification of the copper-binding ligands of lysyl oxidase
Published in Journal of Neural Transmission (01-07-2011)“…In order to identify the ligands coordinating with copper in lysyl oxidase, the enzyme was expressed in an E. coli expression system and active enzyme obtained…”
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Comparing hydrazine-derived reactive groups as inhibitors of quinone-dependent amine oxidases
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2017)“…Lysyl oxidase has emerged as an important enzyme in cancer metastasis. Its activity has been reported to become upregulated in several types of cancer, and…”
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7
ACTB in cancer
Published in Clinica chimica acta (18-02-2013)“…Beta-actin (ACTB) has traditionally been regarded as an endogenous housekeeping gene and has been widely used as a reference gene/protein in quantifying…”
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Purification of high yields of catalytically active lysyl oxidase directly from Escherichia coli cell culture
Published in Protein expression and purification (01-11-2010)“…Lysyl oxidase is a highly insoluble enzyme requiring high concentrations of urea to solubilize. A method to obtain lysyl oxidase in high yields directly from…”
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The potential role of miR-124-3p in tumorigenesis and other related diseases
Published in Molecular biology reports (01-04-2021)“…MicroRNAs (miRNAs) are a class of single‐stranded noncoding and endogenous RNA molecules with a length of 18–25 nucleotides. Previous work has shown that…”
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Annexin A11 in disease
Published in Clinica chimica acta (20-04-2014)“…Ubiquitously expressed in many cell types, annexin A11 (Anxa11) is a member of the multigene family of Ca2+-regulated phospholipid-dependent and…”
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Role of annexin A6 in cancer
Published in Oncology letters (01-10-2015)“…Annexin A6 (AnxA6) is a member of a conserved superfamily of Ca2+-dependent membrane-binding annexin proteins. It participates in membrane and cytoskeleton…”
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Synthesis, crystal structure, EPR properties, and anti-convulsant activities of binuclear and mononuclear 1,10-phenanthroline and salicylate ternary copper(II) complexes
Published in Journal of inorganic biochemistry (10-04-2002)“…Two ternary Cu(II) complexes of 1,10-phenanthroline (phen) and singly (Hsal −) or dideprotonated (sal 2−) salicylate ligands were synthesized, their X-ray…”
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13
CRKL promotes hepatocarcinoma through enhancing glucose metabolism of cancer cells via activating PI3K/Akt
Published in Journal of cellular and molecular medicine (01-03-2021)“…Abnormal glucose metabolism may contribute to cancer progression. As a member of the CRK (v‐crk sarcoma virus CT10 oncogene homologue) adapter protein family,…”
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Modeling Cu(II) Binding to Peptides Using the Extensible Systematic Force Field
Published in Bioinorganic Chemistry and Applications (2010)“…The utility of the extensible systematic force field (ESFF) was tested for copper(II) binding to a 34-amino-acid Cu(II) peptide, which includes five histidine…”
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Mechanistic Insights into Fe Catalyzed α‐C−H Oxidations of Tertiary Amines
Published in ChemCatChem (12-01-2021)“…We report detailed mechanistic investigations of an iron‐based catalyst system, which allows the α‐C−H oxidation of a wide variety of amines. In contrast to…”
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Identification of the disulfide bonds of lysyl oxidase
Published in Journal of Neural Transmission (01-07-2011)“…Proteolytic digestion of bovine aortic lysyl oxidase followed by tandem mass spectrometry has enabled assignment of all five disulfide bonds. The results…”
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Biochemical, functional and structural characterization of Akbu-LAAO: A novel snake venom l-amino acid oxidase from Agkistrodon blomhoffii ussurensis
Published in Biochimie (01-04-2010)“…An l-amino acid oxidase (Akbu-LAAO) was isolated from the venom of Agkistrodon blomhoffii ussurensis snake using DEAE Sephadex A-50 ion-exchange, Sephadex G-75…”
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High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers
Published in Rapid communications in mass spectrometry (30-10-2008)“…The potential biomarkers for the lymphatic metastatic process of mouse hepatocarcinoma were investigated by using two‐dimensional difference in‐gel…”
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Crystal structure of tetraaquabis(pyrimidin-1-ium-4,6-diolato-κ O 4 )manganese(II)
Published in Acta crystallographica. Section E, Crystallographic communications (01-04-2017)“…The Mn II ion in the structure of the mononuclear title compound, [Mn(C 4 H 3 N 2 O 2 ) 2 (H 2 O) 4 ], is situated on an inversion center and is coordinated by…”
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Crystal structure of tetra-aqua-bis-(pyrimidin-1-ium-4,6-diolato-κ O 4 )manganese(II)
Published in Acta crystallographica. Section E, Crystallographic communications (01-04-2017)“…The Mn ion in the structure of the mononuclear title compound, [Mn(C H N O ) (H O) ], is situated on an inversion center and is coordinated by two O atoms from…”
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