Search Results - "Green, Tony"

The evolving genomic landscape of myeloproliferative neoplasms by Nangalia, Jyoti, Green, Tony R

“…Our understanding of the genetic basis of the Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) has moved forward at a staggering pace over…”
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Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms by Nieborowska-Skorska, Margaret, Maifrede, Silvia, Dasgupta, Yashodhara, Sullivan, Katherine, Flis, Sylwia, Le, Bac Viet, Solecka, Martyna, Belyaeva, Elizaveta A., Kubovcakova, Lucia, Nawrocki, Morgan, Kirschner, Martin, Zhao, Huaqing, Prchal, Josef T., Piwocka, Katarzyna, Moliterno, Alison R., Wasik, Mariusz, Koschmieder, Steffen, Green, Tony R., Skoda, Radek C., Skorski, Tomasz

“…Myeloproliferative neoplasms (MPNs) often carry JAK2(V617F), MPL(W515L), or CALR(del52) mutations. Current treatment options for MPNs include cytoreduction by…”
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S150: TIMING AND CLONAL TRAJECTORY TO CHRONIC MYELOID LEUKAEMIA DRIVEN BY THE PHILADELPHIA CHROMOSOME by Kamizela, Aleksandra, Williams, Nicholas, Lee, Joe, Mane, Karim, Milne, Kate, Green, Tony, Chevassut, Timothy, Huntly, Brian, Baxter, E. Joanna, Nangalia, Jyoti

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From Metcalf to myeloproliferative neoplasms – a personal journey by Green, Tony

“…•Human myeloproliferative neoplasms constitute a biologically fascinating group of chronic myeloid malignancies that arise in the hematopoietic stem cell…”
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1001 – FROM METCALF TO MYELOPROLIFERATIVE MALIGNANCIES – A PERSONAL VOYAGE by Green, Tony

“…Donald Metcalf Award Lecture Since my formative post-doctoral time with Don Metcalf, my lab has increasingly focused on the mechanisms whereby blood stem cells…”
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1026 - JAK/STAT SIGNALLING, STEM CELL SUBVERSION AND MYELOID MALIGNANCIES by Green, Tony

“…Our research focuses on the mechanisms whereby blood stem cells are subverted during the genesis of haematological malignancies.  We have increasingly…”
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Age and aging in blood disorders: EHA theme of the year 2013-2014 by Chomienne, Christine, McCann, Shaun, Green, Tony, Hagenbeek, Anton, Lacombe, Catherine, Guenova, Margarita, Roberts, Irene, van der Beek, Ineke

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Nickel Sulfide Ores and Impact Melts: Origin of the Sudbury Igneous Complex (P.C. Lightfoot) by Green, Tony

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The Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues by VAN ETTEN, Richard A, KOSCHMIEDER, Steffen, GALE, Robert Peter, GOLDMAN, John, DELHOMMEAU, Francois, PERROTTI, Danilo, HOLYOAKE, Tessa, PARDANANI, Animesh, MESA, Ruben, GREEN, Tony, IBRAHIM, Amr R, MUGHAL, Tariq

“…This review focuses on topical issues in the biology and treatment of the myeloproliferative neoplasms (MPNs). Studies in transgenic mice suggest that BCR-ABL1…”
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landscape/inscape by Tony Green

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Use spirometry first to improve diagnosis of asthma, says NICE by Green, Tony

“…Clinicians should use spirometry - the measurement of breath - as the first test for asthma in adults and children over five, says draft guidance by the…”
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3006 – JAK2 PHOSPHORYLATES THE RNA PROCESSING PROTEIN HNRNPA1 TO REPRESS THE EXPRESSION OF RETROTRANSPOSONS AND PROTECT THE HAEMATOPOIETIC STEM CELL GENOME by Loughran, Stephen, Deuel, Jeremy, Green, Tony, Oellerich, Thomas

“…The JAK2 kinase phosphorylates tyrosines on key signalling proteins upon the activation of cytokine receptors, and is therefore an essential component of the…”
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Macmillan raises concerns that Liverpool Care Pathway is still used by Green, Tony

“…Controversial end of life framework the Liverpool Care Pathway (LCP) is still being used in some places six months after it was withdrawn, MPs have been told…”
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Safe staffing legislation will change behaviour, says RCN Wales director by Green, Tony

“…Soaring spend on agency nurses in Wales could be cut if minimum staffing levels are introduced in hospitals, Welsh Assembly members have been told…”
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Diagnosis and treatment plan aims to eliminate TB across England by Green, Tony

“…A national drive to eradicate tuberculosis has been launched amid fears that within four years there could be more cases of the potentially fatal disease in…”
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Innovative nursing research unit to encourage evidence-based practice by Green, Tony

“…Speaking up about unsafe practice and the use of technology to prevent patient falls are among the initial projects being investigated at a new nursing…”
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RCN calls for suspension of London maternity unit closure and A&E downgrades by Green, Tony

“…The RCN has called for the suspension of plans to close a maternity unit and downgrade two emergency rooms in London until guarantees can be made about…”
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Five-year plan to tackle TB launched as rates in England threaten to overtake those of US by Green, Tony

“…A national drive to eradicate tuberculosis has been launched amid fears that within four years there could be more cases of the potentially fatal disease in…”
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Report into sudden infant deaths in Wales recommends training for front line healthcare workers by Green, Tony

“…Regular training to ensure front line professionals are aware of the key messages associated with unexplained sudden infant deaths is among recommendations set…”
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Regulator issues alert over faulty insulin pump by Green, Tony

“…People with diabetes have been urged to check an insulin pump after a fault was discovered that could affect when a dosage is administered…”
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