Search Results - "Green, Richard R."

Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq by Swanson, Elliott, Lord, Cara, Reading, Julian, Heubeck, Alexander T, Genge, Palak C, Thomson, Zachary, Weiss, Morgan DA, Li, Xiao-Jun, Savage, Adam K, Green, Richard R, Torgerson, Troy R, Bumol, Thomas F, Graybuck, Lucas T, Skene, Peter J

“…Single-cell measurements of cellular characteristics have been instrumental in understanding the heterogeneous pathways that drive differentiation, cellular…”
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Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy by Barrenäs, Fredrik, Hansen, Scott G, Law, Lynn, Driscoll, Connor, Green, Richard R, Smith, Elise, Chang, Jean, Golez, Inah, Urion, Taryn, Peng, Xinxia, Whitmore, Leanne, Newhouse, Daniel, Hughes, Colette M, Morrow, David, Randall, Kurt T, Selseth, Andrea N, Ford, Julia C, Gilbride, Roxanne M, Randall, Bryan E, Ainslie, Emily, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J, Axthelm, Michael K, Fukazawa, Yoshinori, Pavlakis, George N, Felber, Barbara K, Fourati, Slim, Sekaly, Rafick-Pierre, Lifson, Jeffrey D, Komorowski, Jan, Kosmider, Ewelina, Shao, Danica, Song, Wenjun, Edlefsen, Paul T, Picker, Louis J, Gale, Jr, Michael

“…Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with strain 68-1 Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV…”
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Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism by Tisoncik-Go, Jennifer, Gasper, David J., Kyle, Jennifer E., Eisfeld, Amie J., Selinger, Christian, Hatta, Masato, Morrison, Juliet, Korth, Marcus J., Zink, Erika M., Kim, Young-Mo, Schepmoes, Athena A., Nicora, Carrie D., Purvine, Samuel O., Weitz, Karl K., Peng, Xinxia, Green, Richard R., Tilton, Susan C., Webb-Robertson, Bobbie-Jo, Waters, Katrina M., Metz, Thomas O., Smith, Richard D., Kawaoka, Yoshihiro, Suresh, M., Josset, Laurence, Katze, Michael G.

“…Pandemic influenza viruses modulate proinflammatory responses that can lead to immunopathogenesis. We present an extensive and systematic profiling of lipids,…”
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Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control by Barrenas, Fredrik, Raehtz, Kevin, Xu, Cuiling, Law, Lynn, Green, Richard R., Silvestri, Guido, Bosinger, Steven E., Nishida, Andrew, Li, Qingsheng, Lu, Wuxun, Zhang, Jianshui, Thomas, Matthew J., Chang, Jean, Smith, Elise, Weiss, Jeffrey M., Dawoud, Reem A., Richter, George H., Trichel, Anita, Ma, Dongzhu, Peng, Xinxia, Komorowski, Jan, Apetrei, Cristian, Pandrea, Ivona, Gale, Michael

“…Natural hosts of simian immunodeficiency virus (SIV) avoid AIDS despite lifelong infection. Here, we examined how this outcome is achieved by comparing a…”
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Annotation of long non-coding RNAs expressed in Collaborative Cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts by Josset, Laurence, Tchitchek, Nicolas, Gralinski, Lisa E, Ferris, Martin T, Eisfeld, Amie J, Green, Richard R, Thomas, Matthew J, Tisoncik-Go, Jennifer, Schroth, Gary P, Kawaoka, Yoshihiro, Pardo-Manuel de Villena, Fernando, Baric, Ralph S, Heise, Mark T, Peng, Xinxia, Katze, Michael G

“…The outcome of respiratory virus infection is determined by a complex interplay of viral and host factors. Some potentially important host factors for the…”
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Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART by Fisher, Bridget S, Green, Richard R, Brown, Rachel R, Wood, Matthew P, Hensley-McBain, Tiffany, Fisher, Cole, Chang, Jean, Miller, Andrew D, Bosche, William J, Lifson, Jeffrey D, Mavigner, Maud, Miller, Charlene J, Gale, Jr, Michael, Silvestri, Guido, Chahroudi, Ann, Klatt, Nichole R, Sodora, Donald L

“…Liver disease is a leading contributor to morbidity and mortality during HIV infection, despite the use of combination antiretroviral therapy (cART). The…”
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Author Correction: Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control by Barrenas, Fredrik, Raehtz, Kevin, Xu, Cuiling, Law, Lynn, Green, Richard R., Silvestri, Guido, Bosinger, Steven E., Nishida, Andrew, Li, Qingsheng, Lu, Wuxun, Zhang, Jianshui, Thomas, Matthew J., Chang, Jean, Smith, Elise, Weiss, Jeffrey M., Dawoud, Reem A., Richter, George H., Trichel, Anita, Ma, Dongzhu, Peng, Xinxia, Komorowski, Jan, Apetrei, Cristian, Pandrea, Ivona, Gale, Michael

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Next-generation sequencing of small RNAs from HIV-infected cells identifies phased microrna expression patterns and candidate novel microRNAs differentially expressed upon infection by Chang, Stewart T, Thomas, Matthew J, Sova, Pavel, Green, Richard R, Palermo, Robert E, Katze, Michael G

“…HIV infection of CD4(+) T cells induces a range of host transcriptional changes in mRNAs as well as microRNAs that may coordinate changes in mRNAs. To survey…”
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Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate by Adams Waldorf, Kristina M, Stencel-Baerenwald, Jennifer E, Kapur, Raj P, Studholme, Colin, Boldenow, Erica, Vornhagen, Jay, Baldessari, Audrey, Dighe, Manjiri K, Thiel, Jeff, Merillat, Sean, Armistead, Blair, Tisoncik-Go, Jennifer, Green, Richard R, Davis, Michael A, Dewey, Elyse C, Fairgrieve, Marian R, Gatenby, J Christopher, Richards, Todd, Garden, Gwenn A, Diamond, Michael S, Juul, Sandra E, Grant, Richard F, Kuller, LaRene, Shaw, Dennis W W, Ogle, Jason, Gough, G Michael, Lee, Wonsok, English, Chris, Hevner, Robert F, Dobyns, William B, Gale, Michael, Rajagopal, Lakshmi

“…New animal models of Zika virus (ZIKV) infection are imperative to accelerating efforts to treat or prevent disease in humans. Adams Waldorf et al . now report…”
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Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection by Daniels, Brian P, Jujjavarapu, Harsha, Durrant, Douglas M, Williams, Jessica L, Green, Richard R, White, James P, Lazear, Helen M, Gale, Jr, Michael, Diamond, Michael S, Klein, Robyn S

“…Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR) signaling regulates the responses of endothelial cells of the blood-brain barrier…”
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Genome-Wide Transcriptomic Profiling Reveals Novel Micrornas and Specific Microrna Signatures Associated with Liver Inflammation, Cirrhosis and Hepatocellular Carcinoma in Plasma of Patients with Primary Sclerosing Cholangitis by Handa, Priya, Green, Richard R, Morgan-Stevenson, Vicki, Kowdley, Kris V

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Evidence of cardiac involvement in the fetal inflammatory response syndrome: disruption of gene networks programming cardiac development in nonhuman primates by Mitchell, Timothy, MacDonald, James W., Srinouanpranchanh, Sengkeo, Bammler, Theodor K., Merillat, Sean, Boldenow, Erica, Coleman, Michelle, Agnew, Kathy, Baldessari, Audrey, Stencel-Baerenwald, Jennifer E., Tisoncik-Go, Jennifer, Green, Richard R., Gale, Michael J., Rajagopal, Lakshmi, Adams Waldorf, Kristina M.

“…Most early preterm births are associated with intraamniotic infection and inflammation, which can lead to systemic inflammation in the fetus. The fetal…”
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Blockade of the Fas/FasL System Improves Pneumococcal Clearance from the Lungs without Preventing Dissemination of Bacteria to the Spleen by Matute-Bello, Gustavo, Liles, W. Conrad, Frevert, Charles W., Dhanireddy, Shireesha, Ballman, Kimberly, Wong, Venus, Green, Richard R., Song, Ho Yeong, Witcher, Derrick R., Jakubowski, Joseph A., Martin, Thomas R.

“…Background. The Fas/FasL system is both proapoptotic and proinflammatory. FasL is inhibited by decoy receptor-3 (DcR3), a naturally occurring decoy receptor…”
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Deep sequencing of HIV-infected cells: insights into nascent transcription and host-directed therapy by Peng, Xinxia, Sova, Pavel, Green, Richard R, Thomas, Matthew J, Korth, Marcus J, Proll, Sean, Xu, Jiabao, Cheng, Yanbing, Yi, Kang, Chen, Li, Peng, Zhiyu, Wang, Jun, Palermo, Robert E, Katze, Michael G

“…Polyadenylated mature mRNAs are the focus of standard transcriptome analyses. However, the profiling of nascent transcripts, which often include…”
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Microrna Profiling Reveals a Signature of Oncogenic Micrornas that are Associated with Colorectal Cancer, Cholangiocarcinoma and Hepatocellular Carcinoma in Patients with Primary Sclerosing Cholangitis Treated with High-Dose Ursodeoxycholic Acid by Handa, Priya, Green, Richard R, Gould, Barbara R, Lindor, Keith D, Kowdley, Kris V

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Next-generation sequencing reveals a controlled immune response to Zaire Ebola virus challenge in cynomolgus macaques immunized with vesicular stomatitis virus expressing Zaire Ebola virus glycoprotein (VSVΔG/EBOVgp) by Barrenas, Fredrik, Green, Richard R, Thomas, Matthew J, Law, G Lynn, Proll, Sean C, Engelmann, Flora, Messaoudi, Ilhem, Marzi, Andrea, Feldmann, Heinz, Katze, Michael G

“…Vesicular stomatitis virus expressing Zaire Ebola virus (EBOV) glycoprotein (VSVΔG/EBOVgp) could be used as a vaccine to meet the 2014 Ebola virus outbreak. To…”
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Deep transcriptional sequencing of mucosal challenge compartment from rhesus macaques acutely infected with simian immunodeficiency virus implicates loss of cell adhesion preceding immune activation by Barrenas, Fredrik, Palermo, Robert E, Agricola, Brian, Agy, Michael B, Aicher, Lauri, Carter, Victoria, Flanary, Leon, Green, Richard R, McLain, Randy, Li, Qingsheng, Lu, Wuxun, Murnane, Robert, Peng, Xinxia, Thomas, Matthew J, Weiss, Jeffrey M, Anderson, David M, Katze, Michael G

“…Pathology resulting from human immunodeficiency virus (HIV) infection is driven by protracted inflammation; the primary loss of CD4(+) T cells is caused by…”
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A comprehensive collection of systems biology data characterizing the host response to viral infection by Aevermann, Brian D., Pickett, Brett E., Kumar, Sanjeev, Klem, Edward B., Agnihothram, Sudhakar, Askovich, Peter S., Bankhead, Armand, Bolles, Meagen, Carter, Victoria, Chang, Jean, Clauss, Therese R.W., Dash, Pradyot, Diercks, Alan H., Eisfeld, Amie J., Ellis, Amy, Fan, Shufang, Ferris, Martin T., Gralinski, Lisa E., Green, Richard R., Gritsenko, Marina A., Hatta, Masato, Heegel, Robert A., Jacobs, Jon M., Jeng, Sophia, Josset, Laurence, Kaiser, Shari M., Kelly, Sara, Law, G. Lynn, Li, Chengjun, Li, Jiangning, Long, Casey, Luna, Maria L., Matzke, Melissa, McDermott, Jason, Menachery, Vineet, Metz, Thomas O., Mitchell, Hugh, Monroe, Matthew E., Navarro, Garnet, Neumann, Gabriele, Podyminogin, Rebecca L., Purvine, Samuel O., Rosenberger, Carrie M., Sanders, Catherine J., Schepmoes, Athena A., Shukla, Anil K., Sims, Amy, Sova, Pavel, Tam, Vincent C., Tchitchek, Nicolas, Thomas, Paul G., Tilton, Susan C., Totura, Allison, Wang, Jing, Webb-Robertson, Bobbie-Jo, Wen, Ji, Weiss, Jeffrey M., Yang, Feng, Yount, Boyd, Zhang, Qibin, McWeeney, Shannon, Smith, Richard D., Waters, Katrina M., Kawaoka, Yoshihiro, Baric, Ralph, Aderem, Alan, Katze, Michael G., Scheuermann, Richard H.

“…The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate…”
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Assessment and improvement of Indian-origin rhesus macaque and Mauritian-origin cynomolgus macaque genome annotations using deep transcriptome sequencing data by Peng, Xinxia, Pipes, Lenore, Xiong, Hao, Green, Richard R., Jones, Daniel C., Ruzzo, Walter L., Schroth, Gary P., Mason, Christopher E., Palermo, Robert E., Katze, Michael G.

“…Background The genome annotations of rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques, two of the most common non‐human primate animal…”
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646 - Genome-Wide Transcriptomic Profiling Reveals Novel Micrornas and Specific Microrna Signatures Associated with Liver Inflammation, Cirrhosis and Hepatocellular Carcinoma in Plasma of Patients with Primary Sclerosing Cholangitis by Handa, Priya, Green, Richard R., Morgan-Stevenson, Vicki, Kowdley, Kris V.

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