Search Results - "Green, Pamela"

HCV eradication induced by direct-acting antiviral agents reduces the risk of hepatocellular carcinoma by Ioannou, George N., Green, Pamela K., Berry, Kristin

“…[Display omitted] •DAA-induced SVR is associated with a 71% reduction in HCC risk.•SVR is associated with a similar reduction in HCC risk no matter what…”
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Trends in Burden of Cirrhosis and Hepatocellular Carcinoma by Underlying Liver Disease in US Veterans, 2001–2013 by Beste, Lauren A, Leipertz, Steven L, Green, Pamela K, Dominitz, Jason A, Ross, David, Ioannou, George N

“…Background & Aims Cirrhosis and hepatocellular carcinoma (HCC) are predicted to increase in the United States but the accuracy of prior forecasts and the…”
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Denitrification in wetlands: A review towards a quantification at global scale by Martínez-Espinosa, Columba, Sauvage, Sabine, Al Bitar, Ahmad, Green, Pamela A., Vörösmarty, Charles J., Sánchez-Pérez, José Miguel

“…Research to understand the nitrogen cycle has been thriving. The production of reactive nitrogen by humans exceeds the removal capacity through denitrification…”
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Increased Risk for Hepatocellular Carcinoma Persists Up to 10 Years After HCV Eradication in Patients With Baseline Cirrhosis or High FIB-4 Scores by Ioannou, George N., Beste, Lauren A., Green, Pamela K., Singal, Amit G., Tapper, Elliot B., Waljee, Akbar K., Sterling, Richard K., Feld, Jordan J., Kaplan, David E., Taddei, Tamar H., Berry, Kristin

“…It is unclear if hepatocellular carcinoma (HCC) risk declines over time after hepatitis C virus (HCV) eradication. We analyzed changes in HCC annual incidence…”
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The association between race/ethnicity and the effectiveness of direct antiviral agents for hepatitis C virus infection by Su, Feng, Green, Pamela K., Berry, Kristin, Ioannou, George N.

“…Black race and Hispanic ethnicity were associated with lower rates of sustained virologic response (SVR) to interferon‐based treatments for chronic hepatitis C…”
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Water on an urban planet: Urbanization and the reach of urban water infrastructure by McDonald, Robert I., Weber, Katherine, Padowski, Julie, Flörke, Martina, Schneider, Christof, Green, Pamela A., Gleeson, Thomas, Eckman, Stephanie, Lehner, Bernhard, Balk, Deborah, Boucher, Timothy, Grill, Günther, Montgomery, Mark

“…•We surveyed the water infrastructure of the world's large cities.•Cumulatively, cities moved 504 billion liters/day a distance of 27,000±3800km.•Previous…”
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tRNA cleavage is a conserved response to oxidative stress in eukaryotes by Thompson, Debrah M, Lu, Cheng, Green, Pamela J, Parker, Roy

“…Recent results have identified a diversity of small RNAs in a wide range of organisms. In this work, we demonstrate that Saccharomyces cerevisiae contains a…”
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Effectiveness of Sofosbuvir, Ledipasvir/Sofosbuvir, or Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir Regimens for Treatment of Patients With Hepatitis C in the Veterans Affairs National Health Care System by Ioannou, George N, Beste, Lauren A, Chang, Michael F, Green, Pamela K, Lowey, Elliot, Tsui, Judith I, Su, Feng, Berry, Kristin

“…Background & Aims We investigated the real-world effectiveness of sofosbuvir, ledipasvir/sofosbuvir, and paritaprevir/ritonavir/ombitasvir and dasabuvir (PrOD)…”
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Improvement in Glycemic Control of Type 2 Diabetes After Successful Treatment of Hepatitis C Virus by Hum, Justine, Jou, Janice H, Green, Pamela K, Berry, Kristin, Lundblad, James, Hettinger, Barbara D, Chang, Michael, Ioannou, George N

“…Hepatitis C virus (HCV) infection is associated with diabetes and may worsen glycemic control in patients with diabetes. We aimed to investigate whether…”
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Development of models estimating the risk of hepatocellular carcinoma after antiviral treatment for hepatitis C by Ioannou, George N., Green, Pamela K., Beste, Lauren A., Mun, Elijah J., Kerr, Kathleen F., Berry, Kristin

“…[Display omitted] •We developed and validated models to estimate HCC risk after antiviral treatment for HCV.•Using these models may improve HCC screening…”
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XRN 5′→3′ exoribonucleases: Structure, mechanisms and functions by Nagarajan, Vinay K., Jones, Christopher I., Newbury, Sarah F., Green, Pamela J.

“…The XRN family of 5′→3′ exoribonucleases is critical for ensuring the fidelity of cellular RNA turnover in eukaryotes. Highly conserved across species, the…”
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Nitrate-responsive miR393/AFB3 regulatory module controls root system architecture in Arabidopsis thaliana by Vidal, Elena A, Araus, Viviana, Lu, Cheng, Parry, Geraint, Green, Pamela J, Coruzzi, Gloria M, Gutiérrez, Rodrigo A

“…One of the most striking examples of plant developmental plasticity to changing environmental conditions is the modulation of root system architecture (RSA) in…”
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Effectiveness of hepatitis C antiviral treatment in a USA cohort of veteran patients with hepatocellular carcinoma by Beste, Lauren A, Green, Pamela K, Berry, Kristin, Kogut, Matthew J, Allison, Stephen K, Ioannou, George N

“…Graphical abstract…”
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Urban growth, climate change, and freshwater availability by McDonald, Robert I, Green, Pamela, Balk, Deborah, Fekete, Balazs M, Revenga, Carmen, Todd, Megan, Montgomery, Mark

“…Nearly 3 billion additional urban dwellers are forecasted by 2050, an unprecedented wave of urban growth. While cities struggle to provide water to these new…”
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Massive Analysis of Rice Small RNAs: Mechanistic Implications of Regulated MicroRNAs and Variants for Differential Target RNA Cleavage by Jeong, Dong-Hoon, Park, Sunhee, Zhai, Jixian, Gurazada, Sai Guna Ranjan, De Paoli, Emanuele, Meyers, Blake C., Green, Pamela J.

“…Small RNAs have a variety of important roles in plant development, stress responses, and other processes. They exert their influence by guiding mRNA cleavage,…”
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Differences in hepatocellular carcinoma risk, predictors and trends over time according to etiology of cirrhosis by Ioannou, George N, Green, Pamela, Lowy, Elliott, Mun, Elijah J, Berry, Kristin

“…Hepatocellular carcinoma (HCC) risk is high in cirrhosis. We sought to describe differences in HCC risk, predictors and trends over time according to etiology…”
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Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs by Cole, Christian, Sobala, Andrew, Lu, Cheng, Thatcher, Shawn R, Bowman, Andrew, Brown, John W S, Green, Pamela J, Barton, Geoffrey J, Hutvagner, Gyorgy

“…Deep sequencing technologies such as Illumina, SOLiD, and 454 platforms have become very powerful tools in discovering and quantifying small RNAs in diverse…”
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Freshwater ecosystem services supporting humans: Pivoting from water crisis to water solutions by Green, Pamela A., Vörösmarty, Charles J., Harrison, Ian, Farrell, Tracy, Sáenz, Leonard, Fekete, Balázs M.

“…•Freshwater provisioning index maps upstream water sources supporting humans downstream.•82% of global population is served by freshwater provisions exposed to…”
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MicroRNAs as master regulators of the plant NB-LRR defense gene family via the production of phased, trans-acting siRNAs by Zhai, Jixian, Jeong, Dong-Hoon, De Paoli, Emanuele, Park, Sunhee, Rosen, Benjamin D, Li, Yupeng, González, Alvaro J, Yan, Zhe, Kitto, Sherry L, Grusak, Michael A, Jackson, Scott A, Stacey, Gary, Cook, Douglas R, Green, Pamela J, Sherrier, D Janine, Meyers, Blake C

“…Legumes and many nonleguminous plants enter symbiotic interactions with microbes, and it is poorly understood how host plants respond to promote beneficial,…”
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RNA degradomes reveal substrates and importance for dark and nitrogen stress responses of Arabidopsis XRN4 by Nagarajan, Vinay K, Kukulich, Patrick M, von Hagel, Bryan, Green, Pamela J

“…XRN4, the plant cytoplasmic homolog of yeast and metazoan XRN1, catalyzes exoribonucleolytic degradation of uncapped mRNAs from the 5' end. Most studies of…”
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