Search Results - "Green, Louisa"
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Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function
Published in Nature communications (01-10-2019)“…TCR-gene-transfer is an efficient strategy to produce therapeutic T cells of defined antigen specificity. However, there are substantial variations in the cell…”
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AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival
Published in Journal for immunotherapy of cancer (01-09-2023)“…Background AUTO1 is a fast off-rate CD19-targeting chimeric antigen receptor (CAR), which has been successfully tested in adult lymphoblastic leukemia…”
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Real-Time Continuous Glucose Monitoring Significantly Reduces Severe Hypoglycemia in Hypoglycemia-Unaware Patients With Type 1 Diabetes
Published in Diabetes care (01-12-2013)“…To evaluate the effect of continuous glucose monitoring (CGM) on the frequency of severe hypoglycemia (SH) in patients with established hypoglycemia…”
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Development of a Phase 1 Study Evaluating the Activity of Modular CAR T for Multiple Myeloma (MCARTY) Targeting BCMA and CD19 for Improved Persistence
Published in Blood (02-11-2023)“…BCMA directed CAR T cell therapy for multiple myeloma (MM) shows promise, but very long-term survival may be limited. Notably, BCMA CAR T persistence in MM is…”
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Safety and Efficacy of AUTO1, a Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)
Published in Blood (23-11-2021)“…INTRODUCTION We have previously described AUTO1, a CD19 CAR with a fast off-rate CD19 binding domain, designed to reduce CAR-T immune toxicity and improve…”
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Evaluation of the Effect of Carbohydrate Intake on Postprandial Glucose in Patients With Type 1 Diabetes Treated With Insulin Pumps
Published in Journal of diabetes science and technology (01-11-2016)“…Background: It has been suggested that dietary freedom in functional insulin therapy may be detrimental to glycemic control in type 1 diabetes. This study…”
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Development of an anti-CD2/CD3/CD28 bead-based T-cell proliferation assay
Published in Bioscience horizons (08-12-2014)Get full text
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Teaching Assistants' Experiences of Supporting Pupils in a Mainstream Primary School Context : an Interpretative Phenomenological Analysis
Published 01-01-2017“…Teaching Assistants (TAs) can play an important role in the educational support for pupils with Special Educational Needs (SEN). The broad aim of this study…”
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Dissertation -
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Public and Private in Social Life . S. I. Benn , G. F. Gaus
Published in Ethics (01-04-1986)Get full text
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Barrington Moore, Jr., "Privacy" (Book Review)
Published in Ethics (01-04-1986)Get full text
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S. I. Benn and G. F. Gaus, eds., "Public and Private in Social Life" (Book Review)
Published in Ethics (01-04-1986)Get full text
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