Search Results - "Green, Kathy A."

Myeloid-Derived Suppressor Cells in Murine Retrovirus-Induced AIDS Inhibit T- and B-Cell Responses In Vitro That Are Used To Define the Immunodeficiency by Green, Kathy A, Cook, W James, Green, William R

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Depletion of monocytic myeloid-derived suppressor cells in LP-BM5 murine retroviral infection has a positive impact on virus-induced host immunodeficiency by Green, Kathy A., Ma, Chi, Hoffmann, Fukun W., Hoffmann, Peter R., Green, William R.

“…We have shown the induction of CD11b+Ly6C+ monocytic myeloid-derived suppressor cells (M-MDSCs) during infection of B6 mice by LP-BM5 immunodeficiency-inducing…”
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Upregulated selenoprotein I during lipopolysaccharide-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM-secreting plasma B cells by Ma, Chi, Hoffmann, FuKun W, Shay, Ashley E, Koo, Imhoi, Green, Kathy A, Green, William R, Hoffmann, Peter R

“…Abstract The mechanisms driving metabolic reprogramming during B cell activation are unclear, particularly roles for enzymatic pathways involved in lipid…”
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Inhibition of myeloid-derived suppressor cell (MDSC) activity by redox-modulating agents restores T and B cell proliferative responses in murine AIDS by Fraternale, Alessandra, Green, Kathy A., Schiavano, Giuditta F., Bruschi, Michela, Retini, Michele, Magnani, Mauro, Green, William R.

“…[Display omitted] The mechanisms by which myeloid-derived suppressor cells (MDSCs) mediate inhibition prominently include the production of reactive nitrogen…”
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The Programmed Death-1 and Interleukin-10 Pathways Play a Down-Modulatory Role in LP-BM5 Retrovirus-Induced Murine Immunodeficiency Syndrome by GREEN, Kathy A, OKAZAKI, Taku, HONJO, Tasuku, COOK, W. James, GREEN, William R

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Selective Involvement of the Checkpoint Regulator VISTA in Suppression of B-Cell, but Not T-Cell, Responsiveness by Monocytic Myeloid-Derived Suppressor Cells from Mice Infected with an Immunodeficiency-Causing Retrovirus by Green, Kathy A, Wang, Li, Noelle, Randolph J, Green, William R

“…Inhibition of T-cell responses in tumor microenvironments by myeloid-derived suppressor cells (MDSCs) is widely accepted. We demonstrated augmentation of…”
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Pseudomonas aeruginosa Cif Protein Enhances the Ubiquitination and Proteasomal Degradation of the Transporter Associated with Antigen Processing (TAP) and Reduces Major Histocompatibility Complex (MHC) Class I Antigen Presentation by Bomberger, Jennifer M., Ely, Kenneth H., Bangia, Naveen, Ye, Siying, Green, Kathy A., Green, William R., Enelow, Richard I., Stanton, Bruce A.

“…Cif (PA2934), a bacterial virulence factor secreted in outer membrane vesicles by Pseudomonas aeruginosa, increases the ubiquitination and lysosomal…”
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Subpopulations of M-MDSCs from mice infected by an immunodeficiency-causing retrovirus and their differential suppression of T- vs B-cell responses by O’Connor, Megan A, Fu, Whitney W, Green, Kathy A, Green, William R

“…Abstract Monocytic (CD11b+ Ly6G±/Lo Ly6C+ ) myeloid derived suppressor cells (M-MDSCs) expand following murine retroviral LP-BM5 infection and suppress ex vivo…”
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CD40-Associated TRAF 6 Signaling Is Required for Disease Induction in a Retrovirus-Induced Murine Immunodeficiency by GREEN, Kathy A, AHONEN, Cory L, COOK, W. James, GREEN, William R

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The CD154/CD40 Interaction Required for Retrovirus-Induced Murine Immunodeficiency Syndrome Is Not Mediated by Upregulation of the CD80/CD86 Costimulatory Molecules by Green, Kathy A, Cook, W James, Sharpe, Arlene H, Green, William R

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Alternative translational reading frames as a novel source of epitopes for an expanded CD8 T-cell repertoire: use of a retroviral system to assess the translational requirements for CTL recognition and lysis by Carlson, Timothy L, Green, Kathy A, Green, William R

“…CD8 T-cell responses constitute a key host defense mechanism against tumor cells and a variety of viral infections, including retroviral infections that lead…”
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5-Fluorouracil depletion of Myeloid Derived Suppressor Cells in mice infected with LP-BM5 retrovirus by Green, Kathy A., Green, William R.

“…Abstract Tumor associated MDSC inhibit tumor-directed T-cell responses. We have shown the induction of monocytic MDSCs (M-MDSC) during infection of B6 mice by…”
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MiR-155 and LP-BM5 retrovirus-augmented Monocytic myeloid derived suppressor cells, are players in a profound murine immunodeficiency-causing syndrome by Green, Kathy A, Green, William R

“…Abstract We have shown augmentation of monocytic MDSCs (M-MDSCs) during a profound immunodeficiency causing LP-BM5 retrovirus infection of B6 mice. Enriched…”
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HIF-1α is essential for T cell suppression by murine LP-BM5 retrovirus infection-augmented Monocytic Myeloid Derived Suppressor Cells by Green, Kathy A, Cramer, Robert A, Green, William R

“…Abstract Compared to naïve mice, monocytic myeloid-derived suppressor cells (M-MDSCs) increase in number, and suppressive efficiency, after infection with the…”
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Quantitative analysis of LP-BM5 murine leukemia retrovirus RNA using real-time RT-PCR by Cook, W.James, Green, Kathy A., Obar, Joshua J., Green, William R.

“…Murine AIDS (MAIDS) develops in susceptible mouse strains after infection with the LP-BM5 murine leukemia virus (MuLV) complex that contains a mixture of…”
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Immune CD8+ T Cells Prevent Reactivation of Toxoplasma gondii Infection in the Immunocompromised Host by KHAN, I. A, GREEN, W. R, KASPER, L. H, GREEN, K. A, SCHWARTZMAN, J. D

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Characterization of the CD154-Positive and CD40-Positive Cellular Subsets Required for Pathogenesis in Retrovirus-Induced Murine Immunodeficiency by Green, K A, Noelle, R J, Durell, B G, Green, W R

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Upregulated Selenoprotein I during LPS-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM secreting plasma B cells by Ma, Chi, Hoffmann, FuKun W, Shay, Ashley E, Koo, Imhoi, Green, Kathy A, Green, William R, Hoffmann, Peter R

“…The mechanisms driving metabolic reprogramming during B cell activation are unclear, particularly roles for enzymatic pathways involved in lipid remodeling. We…”
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Checkpoint Regulator VISTA plays a role in Suppression of B-Cell Responsiveness by Monocytic Myeloid Derived Suppressor Cells from LP-BM5 retrovirus-infected Mice by Green, Kathy A, Noelle, Randolph J, Green, William R, Wang, Li

“…Abstract MDSC inhibition of tumor directed T cell responses is well described. We have reported an increase of monocytic MDSC (M-MDSC) during infection of B6…”
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The Programmed Death-1 and Interleukin-10 pathways play a down-modulatory role in LP-BM5 retrovirus-induced murine immunodeficiency syndrome (44.9) by Green, Kathy A, Honjo, Tasuku, Green, William R.

“…Abstract We have focused on studying pathology due to the immune system's response to viral infections. In C57BL/6 mice the retroviral isolate LP-BM5 induces…”
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