Search Results - "Green, DJ"

Pharmacogenomic information in FDA-approved drug labels: Application to pediatric patients by Green, DJ, Mummaneni, P, Kim, IW, Oh, JM, Pacanowski, M, Burckart, GJ

“…Pharmacogenomic (PGx) information is increasingly being incorporated into US Food and Drug Administration‐approved drug labels. We reviewed the data source…”
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P19-23. Putative prefusion mechanism of HIV-1 Env revealed by ligand-induced quaternary alterations in o-gp140 trimers by Moscoso, C G, Kan, E, Poon, S, Sun, Y, Martin, L, Xing, L, Green, D J, Lin, F, Barnett, S, Srivastava, I, Cheng, R

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Opioid use among low back pain patients in primary care: Is opioid prescription associated with disability at 6-month follow-up? by Ashworth, Julie, Green, Daniel J., Dunn, Kate M., Jordan, Kelvin P.

“…Opioid prescription at baseline was significantly associated with greater self-reported disability in back pain patients at 6months after adjusting for…”
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Effect of exercise training on endothelium-derived nitric oxide function in humans by Green, Daniel J., Maiorana, Andrew, O'Driscoll, Gerry, Taylor, Roger

“…Vascular endothelial function is essential for maintenance of health of the vessel wall and for vasomotor control in both conduit and resistance vessels. These…”
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Association between atherogenic risk-modulating proteins and endothelium-dependent flow-mediated dilation in coronary artery disease patients by Tryfonos, Andrea, Mills, Joseph, Green, Daniel J., Wagenmakers, Anton J. M., Dawson, Ellen A., Cocks, Matthew

“…Purpose Endothelial dysfunction is an early and integral event in the development of atherosclerosis and coronary artery disease (CAD). Reduced NO…”
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Adolescent dosing and labeling since the Food and Drug Administration Amendments Act of 2007 by Momper, Jeremiah D, Mulugeta, Yeruk, Green, Dionna J, Karesh, Alyson, Krudys, Kevin M, Sachs, Hari C, Yao, Lynn P, Burckart, Gilbert J

“…During pediatric drug development, dedicated pharmacokinetic studies are generally performed in all relevant age groups to support dose selection for…”
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Obesity and Pediatric Drug Development by Vaughns, Janelle D., Conklin, Laurie S., Long, Ying, Zheng, Panli, Faruque, Fahim, Green, Dionna J., den Anker, John N., Burckart, Gilbert J.

“…There is a lack of dosing guidelines for use in obese children. Moreover, the impact of obesity on drug safety and clinical outcomes is poorly defined. The…”
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Surrogate Endpoints in Pediatric Studies Submitted to the US FDA by Green, Dionna J., Sun, Haihao, Burnham, Janelle, Liu, Xiaomei I., Anker, John, Temeck, Jean, Yao, Lynne, McCune, Susan K., Burckart, Gilbert J.

“…The 21st Century Cures Act was passed in December, 2016, and included a number of provisions to facilitate drug approval. Considerable discussion was generated…”
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Primary Endpoints in Pediatric Efficacy Trials Submitted to the US FDA by Green, Dionna J., Burnham, Janelle M., Schuette, Paul, Liu, Xiaomei I., Maas, Brian M., Yao, Lynne, McCune, Susan K., Chen, Joseph, van den Anker, John N., Burckart, Gilbert J.

“…The selection of appropriate endpoints in pediatric drug development trials is a critical aspect of trial design. Given the high pediatric trial failure rate,…”
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Exercise training normalizes vascular dysfunction and improves central adiposity in obese adolescents by Watts, Katie, Beye, Petra, Siafarikas, Aris, Davis, Elizabeth A., Jones, Timothy W., O'Driscoll, Gerard, Green, Daniel J.

“…We sought to characterize the impact of obesity on vascular function in adolescents and to determine whether an exercise program reverses abnormalities in…”
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Comparison of forearm blood flow responses to incremental handgrip and cycle ergometer exercise: relative contribution of nitric oxide by Green, Daniel J., Bilsborough, William, Naylor, Louise H., Reed, Chris, Wright, Jeremy, O'Driscoll, Gerry, Walsh, Jennifer H.

“…The contribution of endothelium-derived nitric oxide (NO) to exercise hyperaemia remains controversial. Disparate findings may, in part, be explained by…”
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Effects of exercise training on vascular function in obese children by Watts, Katie, Beye, Petra, Siafarikas, Aris, O'Driscoll, Gerard, Jones, Timothy W, Davis, Elizabeth A, Green, Daniel J

“…Atherosclerosis is a disease that begins in childhood; endothelial dysfunction is its earliest detectable manifestation, and primary prevention strategies are…”
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Modified Veress needle decompression of tension pneumothorax: a randomized crossover animal study by Lubin, Dafney, Tang, Andrew L, Friese, Randall S, Martin, Matthew, Green, D J, Jones, Trevor, Means, Russell R, Ginwalla, Rashna, O'Keeffe, Terence S, Joseph, Bellal A, Wynne, Julie L, Kulvatunyou, Narong, Vercruysse, Gary, Gries, Lynn, Rhee, Peter

“…The current prehospital standard of care using a large bore intravenous catheter for tension pneumothorax (tPTX) decompression is associated with a high…”
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Sintering stresses and distortion produced by density differences in bi-layer structures by Ravi, Dhurjati, Green, David J.

“…The variations in green density that arise when a powder is consolidated gives rise to strain rate incompatibility between regions that can result in…”
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Acute cardiovascular responses to resistance exercise in anabolic steroids users: A preliminary investigation by Angell, P.J., Green, D.J., Lord, R., Gaze, D., Whyte, G., George, K.P.

“…Anabolic steroid (AS) use has increased in recent years, but the cardiovascular consequences for users is not fully understood. Resistance trained males (AS=7,…”
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Densification and Sintering Viscosity of Low-Temperature Co-Fired Ceramics by Mohanram, Aravind, Messing, Gary L., Green, David J.

“…In this paper, we present sintering and uniaxial viscosity data of three commercial low‐temperature co‐sintered ceramic systems, i.e., DuPont 951Tape (DU),…”
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Comparison of the Mechanical Properties of Single Crystal and Polycrystalline Yttrium Aluminum Garnet by Mezeix, Laurent, Green, David J.

“…Polycrystalline neodymium‐doped yttrium aluminum garnet (YAG), Nd: Y3Al5O12, has been produced in a transparent form and is being considered as a substitute…”
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Fatigue as a precursor to polymyalgia rheumatica: an explorative retrospective cohort study by Green, DJ, Muller, S, Mallen, CD, Hider, SL

“…Objectives: Polymyalgia rheumatica (PMR) is the commonest inflammatory disorder of older adults. Although not part of the recently published classification…”
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Exercise-induced improvement in endothelial dysfunction is not mediated by changes in CV risk factors: pooled analysis of diverse patient populations by Green, Daniel J, Walsh, Jennifer H, Maiorana, Andrew, Best, Matthew J, Taylor, Roger R, O'Driscoll, J Gerard

“…We have pooled data from a series of our exercise training studies undertaken in groups with a broad range of vascular (dys) function to the examine the…”
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Post-Fledging Care, Philopatry and Recruitment in Brown Thornbills by Green, David J., Cockburn, Andrew

“…1. We describe patterns of post-fledging care, dispersal and recruitment in four cohorts of brown thornbills Acanthiza pusilla. We examine what factors…”
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