Search Results - "Green, Brian D"
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A Review of the In Vivo Evidence Investigating the Role of Nitrite Exposure from Processed Meat Consumption in the Development of Colorectal Cancer
Published in Nutrients (05-11-2019)“…The World Cancer Research Fund (WCRF) 2007 stated that the consumption of processed meat is a convincing cause of colorectal cancer (CRC), and therefore, the…”
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Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease
Published in PloS one (24-03-2015)“…This study combined high resolution mass spectrometry (HRMS), advanced chemometrics and pathway enrichment analysis to analyse the blood metabolome of patients…”
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Innovative processing techniques for altering the physicochemical properties of wholegrain brown rice (Oryza sativa L.) - opportunities for enhancing food quality and health attributes
Published in Critical reviews in food science and nutrition (13-11-2019)“…Rice is a globally important staple consumed by billions of people, and recently there has been considerable interest in promoting the consumption of…”
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The bioactive effects of casein proteins on enteroendocrine cell health, proliferation and incretin hormone secretion
Published in Food chemistry (15-11-2016)“…•Casein proteins are not detrimental to enteroendocrine cells.•Beta casein significantly stimulated enteroendocrine cell proliferation.•Most caseins were…”
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Alzheimer's disease–like pathology has transient effects on the brain and blood metabolome
Published in Neurobiology of aging (01-02-2016)“…Abstract The pathogenesis of Alzheimer's disease (AD) is complex involving multiple contributing factors. The extent to which AD pathology affects the…”
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Dynamic queuosine changes in tRNA couple nutrient levels to codon choice in Trypanosoma brucei
Published in Nucleic acids research (16-12-2021)“…Abstract Every type of nucleic acid in cells undergoes programmed chemical post-transcriptional modification. Generally, modification enzymes use substrates…”
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Investigation of the Human Brain Metabolome to Identify Potential Markers for Early Diagnosis and Therapeutic Targets of Alzheimer’s Disease
Published in Analytical chemistry (Washington) (05-02-2013)“…A study combining high resolution mass spectrometry (liquid chromatography-quadrupole time-of-flight-mass spectrometry, UPLC-QTof-MS) and chemometrics for the…”
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Emerging cardiovascular actions of the incretin hormone glucagon‐like peptide‐1: potential therapeutic benefits beyond glycaemic control?
Published in British journal of pharmacology (01-08-2009)“…Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone secreted by the small intestine in response to nutrient ingestion. It has wide‐ranging effects on…”
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Lipid Profiling of Alzheimer's Disease Brain Highlights Enrichment in Glycerol(phospho)lipid, and Sphingolipid Metabolism
Published in Cells (Basel, Switzerland) (29-09-2021)“…Alzheimer's disease (AD) is reported to be closely linked with abnormal lipid metabolism. To gain a more comprehensive understanding of what causes AD and its…”
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Metabolomic Profiling of Bile Acids in Clinical and Experimental Samples of Alzheimer's Disease
Published in Metabolites (17-06-2017)“…Certain endogenous bile acids have been proposed as potential therapies for ameliorating Alzheimer's disease (AD) but their role, if any, in the…”
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Biochemical properties and biological actions of obestatin and its relevence in type 2 diabetes
Published in Peptides (New York, N.Y. : 1980) (01-02-2018)“…•Obestatin is 23-mer C-terminally amidated peptide is derived from preproghrelin.•It has been ascribed a wide range of metabolic effects relevant to type 2…”
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Metabolomics and computational analysis of the role of monoamine oxidase activity in delirium and SARS-COV-2 infection
Published in Scientific reports (20-05-2021)“…Delirium is an acute change in attention and cognition occurring in ~ 65% of severe SARS-CoV-2 cases. It is also common following surgery and an indicator of…”
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Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter
Published in Microbiome (09-09-2020)“…The factors affecting host-pathogen ecology in terms of the microbiome remain poorly studied. Chickens are a key source of protein with gut health heavily…”
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The Application of Metabolomic Techniques in Research Investigating Neurodegenerative Diseases
Published in Metabolites (20-11-2019)“…We live in a world posing many new and different challenges for human health, and one such challenge is the rapidly expanding number of cases of human…”
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1,2,3,4,6-Penta-O-galloyl-d-glucose Interrupts the Early Adipocyte Lifecycle and Attenuates Adiposity and Hepatic Steatosis in Mice with Diet-Induced Obesity
Published in International journal of molecular sciences (06-04-2022)“…Phytochemicals that interrupt adipocyte lifecycle can provide anti-obesity effects. 1,2,3,4,6-penta-O-galloyl-d-glucose (PGG) is a tannin with two isomers that…”
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A Multi-Mode Bioactive Agent Isolated From Ficus microcarpa L. Fill. With Therapeutic Potential for Type 2 Diabetes Mellitus
Published in Frontiers in pharmacology (27-11-2018)“…Type 2 diabetes is a metabolic disorder, characterized by hyperglycemia and glucose intolerance. Natural products and its derived active compounds may be…”
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Dietary inclusion of nitrite-containing frankfurter exacerbates colorectal cancer pathology and alters metabolism in APCmin mice
Published in NPJ science of food (28-12-2022)“…Colorectal cancer (CRC) is the second most prevelant malignancy in Europe and diet is an important modifiable risk factor. Processed meat consumption,…”
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Grape-seed procyanidins modulate cellular membrane potential and nutrient-induced GLP-1 secretion in STC-1 cells
Published in American Journal of Physiology: Cell Physiology (01-03-2014)“…Grape-seed procyanidin extracts (GSPE) modulate glucose homeostasis, and it was suggested that GSPE may achieve this by enhancing the secretion of incretin…”
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Plasma metabolites distinguish dementia with Lewy bodies from Alzheimer's disease: a cross-sectional metabolomic analysis
Published in Frontiers in aging neuroscience (04-01-2024)“…In multifactorial diseases, alterations in the concentration of metabolites can identify novel pathological mechanisms at the intersection between genetic and…”
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Metabolomic changes in tear fluid following zinc biofortification in the BiZiFED nutritional study: a feasibility study
Published in Frontiers in molecular biosciences (10-09-2024)“…Biofortified Zinc Flour to Eliminate Deficiency in Pakistan (BiZiFED) is a nutritional research program that evaluates the impact of consuming zinc…”
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