Search Results - "Greco, M"

A framework for the investigation of pleiotropy in two‐sample summary data Mendelian randomization by Bowden, Jack, Del Greco M, Fabiola, Minelli, Cosetta, Davey Smith, George, Sheehan, Nuala, Thompson, John

“…Mendelian randomization (MR) uses genetic data to probe questions of causality in epidemiological research, by invoking the Instrumental Variable (IV)…”
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Mendelian Randomization as an Approach to Assess Causality Using Observational Data by Sekula, Peggy, Del Greco M, Fabiola, Pattaro, Cristian, Köttgen, Anna

“…Mendelian randomization refers to an analytic approach to assess the causality of an observed association between a modifiable exposure or risk factor and a…”
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Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression by Bowden, Jack, Spiller, Wesley, Del Greco M, Fabiola, Sheehan, Nuala, Thompson, John, Minelli, Cosetta, Davey Smith, George

“…Abstract Background Summary data furnishing a two-sample Mendelian randomization (MR) study are often visualized with the aid of a scatter plot, in which…”
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Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic by Bowden, Jack, Del Greco M, Fabiola, Minelli, Cosetta, Davey Smith, George, Sheehan, Nuala A, Thompson, John R

“…: MR-Egger regression has recently been proposed as a method for Mendelian randomization (MR) analyses incorporating summary data estimates of causal effect…”
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The use of two-sample methods for Mendelian randomization analyses on single large datasets by Minelli, Cosetta, Del Greco M., Fabiola, van der Plaat, Diana A, Bowden, Jack, Sheehan, Nuala A, Thompson, John

“…Abstract Background With genome-wide association data for many exposures and outcomes now available from large biobanks, one-sample Mendelian randomization…”
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Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology by Wittenbecher, C., Cuadrat, R., Johnston, L., Eichelmann, F., Jäger, S., Kuxhaus, O., Prada, M., Del Greco M., F., Hicks, A. A., Hoffman, P., Krumsiek, J., Hu, F. B., Schulze, M. B.

“…Metabolic alterations precede cardiometabolic disease onset. Here we present ceramide- and dihydroceramide-profiling data from a nested case-cohort (type 2…”
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Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome by Greco M, Fabiola Del, Minelli, Cosetta, Sheehan, Nuala A, Thompson, John R

“…Mendelian randomisation (MR) estimates causal effects of modifiable phenotypes on an outcome by using genetic variants as instrumental variables, but its…”
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Epigenetic modifications and noncoding RNAs in cardiac hypertrophy and failure by Greco, Carolina M., Condorelli, Gianluigi

“…Key Points The myocardium adapts to continued stress—either physiological or pathological—by modulating gene expression in its constituent cells Methylation of…”
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Age at menarche and adult body mass index: a Mendelian randomization study by Gill, Dipender, Brewer, Christopher F., Del Greco M, Fabiola, Sivakumaran, Prasanthi, Bowden, Jack, Sheehan, Nuala A., Minelli, Cosetta

“…Background Pubertal timing has psychological and physical sequelae. While observational studies have demonstrated an association between age at menarche and…”
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Hospital surge capacity in a tertiary emergency referral centre during the COVID‐19 outbreak in Italy by Carenzo, L., Costantini, E., Greco, M., Barra, F. L., Rendiniello, V., Mainetti, M., Bui, R., Zanella, A., Grasselli, G., Lagioia, M., Protti, A., Cecconi, M.

“…Summary The first person‐to‐person transmission of the 2019 novel coronavirus in Italy on 21 February 2020 led to an infection chain that represents one of the…”
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Mendelian Randomization by Grover, Sandeep, Del Greco M, Fabiola, Stein, Catherine M, Ziegler, Andreas

“…Confounding and reverse causality have prevented us from drawing meaningful clinical interpretation even in well-powered observational studies. Confounding may…”
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Aneurysm Syndromes Caused by Mutations in the TGF-β Receptor by Loeys, Bart L, Schwarze, Ulrike, Holm, Tammy, Callewaert, Bert L, Thomas, George H, Pannu, Hariyadarshi, De Backer, Julie F, Oswald, Gretchen L, Symoens, Sofie, Manouvrier, Sylvie, Roberts, Amy E, Faravelli, Francesca, Greco, M. Alba, Pyeritz, Reed E, Milewicz, Dianna M, Coucke, Paul J, Cameron, Duke E, Braverman, Alan C, Byers, Peter H, De Paepe, Anne M, Dietz, Harry C

“…Aggressive arterial aneurysms, such as thoracic aortic aneurysms and aortic dissection, were found to be caused by mutations in the genes encoding the…”
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Thyroid Function and Mood Disorders: A Mendelian Randomization Study by Kuś, Aleksander, Kjaergaard, Alisa D, Marouli, Eirini, Del Greco M, Fabiola, Sterenborg, Rosalie B T M, Chaker, Layal, Peeters, Robin P, Bednarczuk, Tomasz, Åsvold, Bjørn O, Burgess, Stephen, Deloukas, Panos, Teumer, Alexander, Ellervik, Christina, Medici, Marco

“…Observational studies suggest that even minor variations in thyroid function are associated with the risk of mood disorders, including major depressive…”
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Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study by Marouli, Eirini, Kus, Aleksander, Del Greco M, Fabiola, Chaker, Layal, Peeters, Robin, Teumer, Alexander, Deloukas, Panos, Medici, Marco

“…Abstract Context Observational studies suggest that variations in normal range thyroid function are associated with cardiovascular diseases. However, it…”
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Entropy-Based Approach for Rating Curve Assessment in Rough and Smooth Irrigation Ditches by Greco, M

“…AbstractThe aim of the present work is to propose an expeditive methodology derived from the one-dimensional (1D) entropy-based model to evaluate the water…”
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How Mindfulness Training Promotes Positive Emotions: Dismantling Acceptance Skills Training in Two Randomized Controlled Trials by Lindsay, Emily K, Chin, Brian, Greco, Carol M, Young, Shinzen, Brown, Kirk W, Wright, Aidan G. C, Smyth, Joshua M, Burkett, Deanna, Creswell, J. David

“…Mindfulness meditation interventions-which train skills in monitoring present-moment experiences with a lens of acceptance-have shown promise for increasing…”
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Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review by Cortegiani, A., Ippolito, M., Greco, M., Granone, V., Protti, A., Gregoretti, C., Giarratano, A., Einav, S., Cecconi, M.

“…Tocilizumab is an IL-6 receptor-blocking agent proposed for the treatment of severe COVID-19. The aim of this systematic review was to describe the rationale…”
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Asthma and incident coronary heart disease: an observational and Mendelian randomisation study by Valencia-Hernández, Carlos A, Del Greco M, Fabiola, Sundaram, Varun, Portas, Laura, Minelli, Cosetta, Bloom, Chloe I

“…Observational studies suggest asthma is a risk factor for coronary heart disease (CHD) and sex modifies the risk, but they may suffer from methodological…”
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Benefits and risks of epidural analgesia in cardiac surgery by Landoni, G., Isella, F., Greco, M., Zangrillo, A., Royse, C.F.

“…Epidurals provide excellent analgesia for cardiac surgery and may reduce complications. However, their use has been tempered because of concern of the rare,…”
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Mendelian randomization: Progressing towards understanding causality by König, Inke R., Greco, Fabiola M. Del

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