Search Results - "Grecian, Scott"

Ruthenium-Catalyzed Cycloaddition of Nitrile Oxides and Alkynes: Practical Synthesis of Isoxazoles by Grecian, Scott, Fokin, Valery V

“…3,4‐Disubstituted and 3,4,5‐trisubstituted isoxazoles have been formed from alkynes and nitrile oxides in a ruthenium(II)‐catalyzed process (see scheme;…”
Get full text

Site-specific protein labeling using PRIME and chelation-assisted click chemistry by Uttamapinant, Chayasith, Sanchez, Mateo I, Liu, Daniel S, Yao, Jennifer Z, White, Katharine A, Grecian, Scott, Clark, Scott, Gee, Kyle R, Ting, Alice Y

“…This protocol describes an efficient method to site-specifically label cell-surface or purified proteins with chemical probes in two steps: probe incorporation…”
Get full text

Double Conjugate Addition of a Nitropropionate Ester to a Quinone Monoketal:  Synthesis of an Advanced Intermediate to (±)-Gelsemine by Grecian, Scott, Aubé, Jeffrey

“…A double conjugate addition between the lithium dianion of ethyl 3-nitropropionate and p-benzoquinone dimethyl ketal afforded a mixture of diastereomeric…”
Get full text

Novel Live Alkaline Phosphatase Substrate for Identification of Pluripotent Stem Cells by Singh, Upinder, Quintanilla, Rene H., Grecian, Scott, Gee, Kyle R., Rao, Mahendra S., Lakshmipathy, Uma

Get full text

Regioselective Single and Double Conjugate Additions to Substituted Cyclohexa-2,5-dienone Monoacetals by Grecian, Scott, Wrobleski, Aaron D, Aubé, Jeffrey

“…A series of quinone monoacetals bearing electron-withdrawing groups was treated with diethyl malonate and other bifunctional nucleophiles in the presence of…”
Get full text

Ruthenium-Catalyzed Cycloaddition of Nitrile Oxides and Alkynes: Practical Synthesis of Isoxazoles by Grecian, Scott, Fokin, Valery V.

“…Di‐ und trisubstituierte Isoxazole sind aus Alkinen und Nitriloxiden mithilfe eines Ruthenium(II)‐katalysierten Prozesses zugänglich (siehe Schema;…”
Get full text

Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling by Uttamapinant, Chayasith, Tangpeerachaikul, Anupong, Grecian, Scott, Clarke, Scott, Singh, Upinder, Slade, Peter, Gee, Kyle R., Ting, Alice Y.

“…Bring your own copper: Copper‐chelating azides undergo much faster click reactions (CuAAC) than nonchelating azides under a variety of biocompatible…”
Get full text

Direct synthesis of trimethyl(2-phenoxyethyl)silanes from aromatic fluorides by Grecian, Scott A., Hadida, Sabine, Warren, Stephen D.

“…[Display omitted] A direct synthesis of trimethyl(2-phenoxyethyl)silanes from the corresponding aromatic fluorides and 2-(trimethylsilyl)ethanol was developed…”
Get full text

Improved click chemistry demonstrating EdU cell proliferation with GFP expressing cells and R-PE based immunophenotyping. (P3299) by Deveny, Ruth, DeMarco, Carolyn, Bradford, Jolene, Clarke, Scott, Grecian, Scott, Singh, Upinder, Gee, Kyle

“…The current Click-iT® EdU kit, for measuring cell proliferation, cannot be use for the simultaneous detection of EdU, GFP and R-PE fluorescence due to the…”
Get full text

Site-specific protein labeling with PRIME and chelation-assisted Click chemistry by Uttamapinant, Chayasith, Sanchez, Mateo I., Liu, Daniel S., Yao, Jennifer Z., White, Katharine A., Grecian, Scott, Clarke, Scott, Gee, Kyle R., Ting, Alice Y.

“…This protocol describes an efficient method to site-specifically label cell-surface or purified proteins with chemical probes in two steps: PRobe Incorporation…”
Get full text

Reactions of Cyclopropanone Acetals with Alkyl Azides:  Carbonyl Addition versus Ring-Opening Pathways by Grecian, Scott, Desai, Pankaj, Mossman, Craig, Poutsma, Jennifer L, Aubé, Jeffrey

“…The Lewis acid-mediated reactions of substituted cyclopropanone acetals with alkyl azides were found to strongly depend on the structure of the ketone…”
Get full text

Novel Live Alkaline Phosphatase Substrate for Identification of Pluripotent Stem Cells by Singh, Upinder, Quintanilla, Rene H., Grecian, Scott, Gee, Kyle R., Rao, Mahendra S., Lakshmipathy, Uma

Get full text

Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling by Uttamapinant, Chayasith, Tangpeerachaikul, Anupong, Grecian, Scott, Clarke, Scott, Singh, Upinder, Slade, Peter, Gee, Kyle R., Ting, Alice Y.

“…Kupfer‐chelatisierende Azide reagieren unter biokompatiblen Bedingungen sehr viel schneller in Klick‐Reaktionen (CuAAC) als nichtchelatisierende Azide. Damit…”
Get full text

Ruthenium‐Catalyzed Cycloaddition of Nitrile Oxides and Alkynes: Practical Synthesis of Isoxazoles by Grecian, Scott, Fokin, Valery V.

Get full text

I. Reactions of cyclopropanones with alkyl azides. II. Double conjugate additions of bis-nucleophiles to quinone monoketals: Formal total synthesis of (±)-gelsemine by Grecian, Scott A

“…The Lewis acid-mediated reactions of substituted cyclopropanone acetals with alkyl azides were examined. When cyclopropanone acetal was treated with alkyl…”
Get full text

I. Reactions of cyclopropanones with alkyl azides. II. Double conjugate additions of bis-nucleophiles to quinone monoketals: Formal total synthesis of (+/-)-gelsemine by Grecian, Scott A

“…The Lewis acid-mediated reactions of substituted cyclopropanone acetals with alkyl azides were examined. When cyclopropanone acetal was treated with alkyl…”
Get full text

Fast, Cell‐Compatible Click Chemistry with Copper‐Chelating Azides for Biomolecular Labeling by Uttamapinant, Chayasith, Tangpeerachaikul, Anupong, Grecian, Scott, Clarke, Scott, Singh, Upinder, Slade, Peter, Gee, Kyle R., Ting, Alice Y.

Get full text