Search Results - "Grechkin, A N"
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1
Specificity of oxidation of linoleic acid homologs by plant lipoxygenases
Published in Biochemistry (Moscow) (01-08-2009)“…The lipoxygenase-catalyzed oxidation of linoleic acid homologs was studied. While the linoleic acid oxidation by maize 9-lipoxygenase (9-LO) specifically…”
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2
Hexadecanoid pathway in plants: Lipoxygenase dioxygenation of (7Z,10Z,13Z)-hexadecatrienoic acid
Published in Biochemistry (Moscow) (01-06-2010)“…7,10,13-Hexadecatrienoic acid (16:3) is abundant in many plant species. However, its metabolism through the lipoxygenase pathway is not sufficiently…”
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3
Epoxyalcohol Synthase RjEAS (CYP74A88) from the Japanese Buttercup (Ranunculus japonicus): Cloning and Characterization of Catalytic Properties
Published in Biochemistry (Moscow) (01-02-2019)“…Cytochromes P450 of the CYP74 family play a key role in the lipoxygenase cascade generating oxylipins (products of polyunsaturated fatty acid oxidation). The…”
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4
The CYP443C1 (CYP74 clan) Cytochrome of Sea Anemone Nematostella vectensis–the First Metazoan Enzyme Possessing Hydroperoxide Lyase/Epoxyalcohol Synthase Activity
Published in Doklady. Biochemistry and biophysics (01-05-2019)“…A novel CYP74 clan gene CYP443С1 of the starlet sea anemone ( Nematostella vectensis , Cnidaria) has been cloned, and the properties of the corresponding…”
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5
Detection of Divinyl Ether Synthase Activity and a Novel Oxylipin (1'Z)–Colneleic Acid in Asparagus (Asparagus officinalis L.)
Published in Russian journal of bioorganic chemistry (2019)“…— The activity of divinyl ether synthase (EC: 4.2.1.121), an enzyme involved in the lipoxygenase cascade of unsaturated fatty acids in plants, has been found…”
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6
Conversion of Tomato Allene Oxide Synthase LeAOS3 (CYP74C3) into Epoxyalcohol Synthase by Site-Directed Mutagenesis
Published in Doklady. Biochemistry and biophysics (01-11-2018)“…The site-directed mutagenesis of tomato allene oxide synthase LeAOS3 (CYP74C3) on the “F/L toggle” site resulted in a partial conversion of LeAOS3 into…”
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7
Antimicrobial Activity of Geometric Isomers of Etherolenic Acid—the Products of Plant Lipoxygenase Cascade
Published in Doklady. Biochemistry and biophysics (01-05-2018)“…Data on the influence of the double bond geometry on the antimicrobial properties of different isomers of etherolenic acid against phytopathogenic bacteria are…”
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8
The lipoxygenase pathway in tulip (Tulipa gesneriana): detection of the ketol route
Published in Biochemical journal (01-12-2000)“…The in vitro metabolism of [1-(14)C]linoleate, [1-(14)C]linolenate and their 9(S)-hydroperoxides was studied in cell-free preparations from tulip (Tulipa…”
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9
Screening of divinyl ether synthase activity in nonphotosynthetic tissue of asparagales
Published in Doklady. Biochemistry and biophysics (01-03-2013)“…The current level of knowledge on plant genomics indicates that the lipoxygenase pathway in plants is regulated by a wide variety of genes. Molecular cloning…”
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10
WITHDRAWN: Structural and mechanistic studies of hydroperoxide conversions catalyzed by a CYP74 clan epoxy alcohol synthase from amphioxus (Branchiostoma floridae)
Published in Journal of lipid research (04-03-2014)“…This manuscript has been withdrawn by the Author…”
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11
Oxidation of glycerolipids by maize 9-lipoxygenase and its A562G mutant
Published in Chemistry and physics of lipids (01-03-2011)“…Lipoxygenases (LOXs) are key enzymes in the biosynthesis of oxylipins, the diverse class of bioregulators involved into developmental processes, signalling and…”
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12
Alteration of the catalytic properties of divinyl ether synthase as a result of substitutions of unique amino acids
Published in Doklady. Biochemistry and biophysics (01-09-2013)“…Recent studies by site directed mutagenesis have shown that single amino acid substitutions in catalytically important sites may result in the conversion of…”
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13
Alteration of catalysis of CYP74C subfamily enzymes as a result of site-directed mutagenesis
Published in Doklady. Biochemistry and biophysics (01-12-2010)“…Enzymes of the lipoxygenase signalling system lipoxygenases and cytochromes P450 of the CYP74 family, which catalyze the formation of oxylipins, oxidizing…”
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14
Origins of the diversity of cytochrome P450 CYP74 family based on the results of site-directed mutagenesis
Published in Moscow University biological sciences bulletin (2010)“…Bioinformatic analysis and site-directed mutagenesis allowed identification of the determinants of catalysis for CYP74, which are located in the central part…”
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15
Identification and primary characterization of novel cytochrome CYP74B1 of flax (Linum usitatissimum)
Published in Doklady. Biochemistry and biophysics (01-10-2011)“…The divinyl ether synthase CYP74B1 of flax is a unique enzyme of the CYP74B subfamily. In accordance with accepted nomenclature of the CYP74 enzymes, we…”
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16
Cyclization of natural allene oxide fatty acids. The anchimeric assistance of beta, gamma-double bond beside the oxirane and the reaction mechanism
Published in Biochimica et biophysica acta (14-07-1994)“…Formation of cyclopentenones was followed from linoleic, alpha-linolenic and gamma-linolenic acid hydroperoxides (HPOD, HPOT(alpha) and HPOT(gamma),…”
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17
Lipoxygenase pathway in tulip: biosynthesis of ketols
Published in Biochemical Society transactions (01-12-2000)“…The metabolism in vitro of [1-(14)C]linoleate, [1-(14)C]linolenate and their 9(S)-hydroperoxides in tulip (Tulipa gesneriana) was found to be under the control…”
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18
Regio- and stereospecificity of recombinant soybean lipoxygenase-2
Published in Doklady. Biochemistry and biophysics (01-08-2007)“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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19
Formation of cyclopentenones from all-( E) hydroperoxides of linoleic acid via allene oxides. New insight into the mechanism of cyclization
Published in FEBS letters (21-01-2000)“…Conversions of ( Z,E)- and ( E,E)-isomers of linoleic acid 13- and 9-hydroperoxides with flax and maize allene oxide synthase were studied. All-( E) but not (…”
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20
Influence of (9Z)-12-hydroxy-9-dodecenoic acid and methyl jasmonate on plant protein phosphorylation
Published in Biochemical Society transactions (01-12-2000)“…The products of the lipoxygenase pathway, methyl jasmonic acid (MeJA) and (9Z)-12-hydroxy-9-dodecenoic acid (HDA), hardly changed the relative level of…”
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