Bone tissue reaction, setting time, solubility, and pH of root repair materials
Objectives This study aims to compare the bone tissue reaction, setting time, solubility, and pH of NeoMTA Plus, Biodentine (BD), and MTA Angelus (MTA-A). Materials and methods Initial and final setting times ( n = 7) and solubility up to 7 days ( n = 11) were evaluated in accordance with ASTM C26...
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Published in: | Clinical oral investigations Vol. 23; no. 3; pp. 1359 - 1366 |
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Main Authors: | , , , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
Berlin/Heidelberg
Springer Berlin Heidelberg
01-03-2019
Springer Nature B.V |
Subjects: | |
Online Access: | Get full text |
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Summary: | Objectives
This study aims to compare the bone tissue reaction, setting time, solubility, and pH of NeoMTA Plus, Biodentine (BD), and MTA Angelus (MTA-A).
Materials and methods
Initial and final setting times (
n
= 7) and solubility up to 7 days (
n
= 11) were evaluated in accordance with ASTM C266–15 and ANSI/ADA Specification No. 57, respectively. pH (
n
= 10) was measured up to 28 days. Bone tissue reactions in 48 rats’ femur were histologically analyzed after 7, 30, and 90 days. ANOVA and Tukey’s tests compared setting time, solubility, and pH data; bone reactions data were compared by Kruskal-Wallis and Dunn’s tests.
Results
NeoMTA Plus had longer initial and final setting times than MTA-A and BD (
P
< 0.05). At 7 days, BD showed the highest solubility, similar to NeoMTA Plus (
P
> 0.05) and different from MTA-A (
P
< 0.05). NeoMTA Plus had a progressive mass loss over time; at 7 days, it was significantly different from the initial mass (
P
< 0.05). BD showed higher pH in the periods assessed when compared to the other materials (
P
< 0.05). Bone tissue repair had no differences between groups in each experimental period (
P
> 0.05). All groups presented no difference from 30 to 90 days (
P
> 0.05) and had better bone repair at 90 days than at 7 days (
P
< 0.05).
Conclusions
NeoMTA Plus, BD, and MTA-A showed satisfactory setting time, high mass loss, alkaline pH, and allowed bone repair.
Clinical relevance
Calcium silicate-based cements are indicated for multiple clinical situations. NeoMTA Plus and BD showed satisfactory physical-chemical and biological properties, being considered as alternatives to MTA-A, as root repair materials for clinical use. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1432-6981 1436-3771 |
DOI: | 10.1007/s00784-018-2564-1 |