Search Results - "Grecco, G."
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Adeno-Associated Viral Vectors in Neuroscience Research
Published in Molecular therapy. Methods & clinical development (12-06-2020)“…Adeno-associated viral vectors (AAVs) are increasingly useful preclinical tools in neuroscience research studies for interrogating cellular and neurocircuit…”
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Alterations of brain microstructures in a mouse model of prenatal opioid exposure detected by diffusion MRI
Published in Scientific reports (12-10-2022)“…Growing opioid use among pregnant women is fueling a crisis of infants born with prenatal opioid exposure. A large body of research has been devoted to…”
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Perturbed neurochemical and microstructural organization in a mouse model of prenatal opioid exposure: A multi-modal magnetic resonance study
Published in PloS one (20-07-2023)“…Methadone-based treatment for pregnant women with opioid use disorder is quite prevalent in the clinical environment. A number of clinical and animal…”
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The role of anterior insular cortex inputs to dorsolateral striatum in binge alcohol drinking
Published in eLife (13-09-2022)“…How does binge drinking alcohol change synaptic function, and do these changes maintain binge consumption? The anterior insular cortex (AIC) and dorsolateral…”
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Prenatal methadone exposure selectively alters protein expression in primary motor cortex: Implications for synaptic function
Published in Frontiers in pharmacology (01-02-2023)“…As problematic opioid use has reached epidemic levels over the past 2 decades, the annual prevalence of opioid use disorder (OUD) in pregnant women has also…”
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Prenatal methadone exposure disrupts behavioral development and alters motor neuron intrinsic properties and local circuitry
Published in eLife (16-03-2021)“…Despite the rising prevalence of methadone treatment in pregnant women with opioid use disorder, the effects of methadone on neurobehavioral development remain…”
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Mortality Analysis of Acute Liver Failure in Uruguay
Published in Transplantation proceedings (01-03-2018)“…Acute liver failure (ALF) is a syndrome with high mortality. Describe characteristics and outcomes of patients with ALF in Uruguay, and identify factors…”
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Risk Factors of Mortality After Liver Transplantation in Uruguay
Published in Transplantation proceedings (01-03-2018)“…Identification of predictive factors of mortality in a liver transplant (LT) program optimizes patient selection and allocation of organs. To determine…”
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9
Lessons Learned From Counting Toes: Reflecting on Medical Errors
Published in Academic medicine (01-08-2020)Get full text
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10
The science of medicine and the art of medicine: A student perspective on the U.S. medical education system
Published in Medical teacher (02-10-2020)“…This personal view about the overemphasis placed on United States Medical Licensing Examination scores and how the U.S. undergraduate medical education system…”
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Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats
Published in Data in brief (01-12-2018)“…The synthetic cathinones methylone, butylone, and pentylone differ from each other through the one carbon lengthening of the α-alkyl chain: methylone (-CH3),…”
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Impact of a Multimodal Approach in Prevention of Surgical Site Infection in Hepatic Transplant Recipients
Published in Transplantation proceedings (01-03-2016)“…Abstract Introduction In liver transplant (LT) recipients, surgical site infection (SSI) represents an important cause of morbidity and mortality. Objective…”
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13
Prenatal opioid administration induces shared alterations to the maternal and offspring gut microbiome: A preliminary analysis
Published in Drug and alcohol dependence (01-10-2021)“…•Maternal opioid use during pregnancy is a growing concern.•Maternal methadone treatment disrupts the microbial diversity in dams and offspring.•16 features in…”
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Effects of prenatal opioid exposure on synaptic adaptations and behaviors across development
Published in Neuropharmacology (01-01-2023)“…In this review, we focus on prenatal opioid exposure (POE) given the significant concern for the mental health outcomes of children with parents affected by…”
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Two Weeks of Continuous Opioid Treatment in an Adenine-Induced Mouse Model of Chronic Kidney Disease Exacerbates the Bone Inflammatory State and Increases Osteoclasts
Published in Calcified tissue international (01-08-2024)“…Patients with chronic kidney disease (CKD) report high pain levels, but reduced renal clearance eliminates many analgesic options; therefore, 30–50% of CKD…”
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Prenatal opioid exposure reprograms the behavioural response to future alcohol reward
Published in Addiction biology (01-03-2022)“…As the opioid crisis has continued to grow, so has the number of infants exposed to opioids during the prenatal period. A growing concern is that prenatal…”
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Alterations in White Matter Microstructure and Connectivity in Young Adults with Alcohol Use Disorder
Published in Alcoholism, clinical and experimental research (01-06-2019)“…Background Magnetic resonance imaging (MRI) studies have shown differences in volume and structure in the brains of individuals with alcohol use disorder…”
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Impact of common clandestine structural modifications on synthetic cathinone “bath salt” pharmacokinetics
Published in Toxicology and applied pharmacology (01-08-2017)“…Since 2009, the synthetic cathinones (“bath salts”) have risen in popularity as drugs of abuse. However, there are a paucity of studies that have determined…”
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Impact of Functional Group Modifications on Designer Phenethylamine Induced Hyperthermia
Published in Chemical research in toxicology (16-05-2016)“…The popularity of designer phenethylamines such as synthetic cathinones (“bath salts”) has led to increased reports of life-threatening hyperthermia. The…”
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A multi‐omic analysis of the dorsal striatum in an animal model of divergent genetic risk for alcohol use disorder
Published in Journal of neurochemistry (01-05-2021)“…The development of selectively bred high and low alcohol‐preferring mice (HAP and LAP, respectively) has allowed for an assessment of the polygenetic risk for…”
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