Search Results - "Grebely, Jason"
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Epidemiology and natural history of HCV infection
Published in Nature reviews. Gastroenterology & hepatology (01-09-2013)“…Globally, 130–170 million people have HCV infection; however, distribution patterns are highly variable. This Review outlines the latest information on the…”
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Global patterns of opioid use and dependence: harms to populations, interventions, and future action
Published in The Lancet (British edition) (26-10-2019)“…We summarise the evidence for medicinal uses of opioids, harms related to the extramedical use of, and dependence on, these drugs, and a wide range of…”
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Direct-acting antiviral agents for HCV infection affecting people who inject drugs
Published in Nature reviews. Gastroenterology & hepatology (01-11-2017)“…Key Points HCV prevalence and incidence among people who inject drugs (PWID) remains high Direct-acting antiviral agents (DAA) for HCV with cure in >95%…”
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Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review
Published in The Lancet global health (01-12-2017)“…Sharing of equipment used for injecting drug use (IDU) is a substantial cause of disease burden and a contributor to blood-borne virus transmission. We did a…”
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Global statistics on alcohol, tobacco and illicit drug use: 2017 status report
Published in Addiction (Abingdon, England) (01-10-2018)“…Aims This review provides an up‐to‐date curated source of information on alcohol, tobacco and illicit drug use and their associated mortality and burden of…”
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Prevention, treatment and care of hepatitis C virus infection among people who inject drugs
Published in The International journal of drug policy (01-02-2015)“…Abstract People who inject drugs (PWID) represent the core of the hepatitis C virus (HCV) epidemic in many countries. HCV transmission continues among PWID,…”
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Global elimination of hepatitis C virus by 2030: why not?
Published in Nature medicine (01-02-2020)“…The World Health Organization’s targets for eliminating hepatitis C virus by 2030 have been deemed ambitious by many. However, we believe they are achievable,…”
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Global, regional, and country-level coverage of interventions to prevent and manage HIV and hepatitis C among people who inject drugs: a systematic review
Published in The Lancet global health (01-12-2017)“…People who inject drugs (PWID) are a key population affected by the global HIV and hepatitis C virus (HCV) epidemics. HIV and HCV prevention interventions for…”
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Hepatitis C reinfection after successful antiviral treatment among people who inject drugs: A meta-analysis
Published in Journal of hepatology (01-04-2020)“…HCV reinfection following successful treatment can compromise treatment outcomes. This systematic review assessed the rate of HCV reinfection following…”
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Direct-acting antiviral treatment for hepatitis C among people who use or inject drugs: a systematic review and meta-analysis
Published in The lancet. Gastroenterology & hepatology (01-11-2018)“…There are concerns around poorer response to direct-acting antiviral (DAA) therapy for hepatitis C virus infection among people who use drugs. This systematic…”
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Management of acute HCV infection in the era of direct-acting antiviral therapy
Published in Nature reviews. Gastroenterology & hepatology (01-07-2018)“…The management of acute HCV infection has not been standardized following the availability of direct-acting antiviral agents (DAAs) for chronic HCV infection,…”
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Prioritization of HCV treatment in the direct-acting antiviral era: An economic evaluation
Published in Journal of hepatology (01-07-2016)“…Graphical abstract…”
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Australia could miss the WHO hepatitis C virus elimination targets due to declining treatment uptake and ongoing burden of advanced liver disease complications
Published in PloS one (16-09-2021)“…Australia was one of the first countries to introduce government-funded unrestricted access to direct-acting antiviral (DAA) therapy, with 88,790 treated since…”
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Mixed HCV infection and reinfection in people who inject drugs—impact on therapy
Published in Nature reviews. Gastroenterology & hepatology (01-04-2015)“…Key Points As a result of ongoing high-risk behaviours, people who inject drugs (PWID) might commonly harbour mixed HCV infections and are at risk of…”
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Hepatitis C virus clearance, reinfection, and persistence, with insights from studies of injecting drug users: towards a vaccine
Published in The Lancet infectious diseases (01-05-2012)“…Summary Hepatitis C virus (HCV) was discovered more than two decades ago, but progress towards a vaccine has been slow. HCV infection will spontaneously clear…”
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Deimplementation in the provision of opioid agonist treatment to achieve equity of care for people engaged in treatment: a qualitative study
Published in Implementation science : IS (09-06-2023)“…Deimplementation, the removal or reduction of potentially hazardous approaches to care, is key to progressing social equity in health. While the benefits of…”
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Timely Hepatitis C RNA Testing and Treatment in the Era of Direct-Acting Antiviral Therapy among People with Hepatitis C in New South Wales, Australia
Published in Viruses (08-07-2022)“…This study aimed to identify the factors associated with timely (within four weeks) HCV RNA testing and timely (within six months) DAA initiation following HCV…”
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Adherence to pan‐genotypic glecaprevir/pibrentasvir and efficacy in HCV‐infected patients: A pooled analysis of clinical trials
Published in Liver international (01-04-2020)“…Background & Aims Adequate adherence to hepatitis C virus (HCV) treatment is believed to be a key component of treatment success because non‐adherence can…”
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Hepatitis C virus testing, liver disease assessment and direct‐acting antiviral treatment uptake and outcomes in a service for people who are homeless in Sydney, Australia: The LiveRLife homelessness study
Published in Journal of viral hepatitis (01-08-2019)“…People who are homeless have increased hepatitis C virus (HCV) infection risk, and are less likely to access primary healthcare. We aimed to evaluate HCV RNA…”
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Estimating the number of people who inject drugs in Australia
Published in BMC public health (29-09-2017)“…Injecting drug use is associated with considerable morbidity and mortality. Estimates of the size of the population of people who inject drugs are critical to…”
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