Search Results - "Grebe, Stefan K.G."

Commentary on Cryptogenic Cushing Syndrome Due to a White Lie by Grebe, Stefan K G

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Improving LC-MS/MS measurements of steroids with differential mobility spectrometry by Chai, Yubo, Grebe, Stefan K.G., Maus, Anthony

“…[Display omitted] •Measurements of many steroids are routinely used for clinical diagnosis.•Specific steroid measurements are challenging due to similarities…”
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Thyroglobulin autoantibodies, thyroid nodules, and new insights into some old questions by Grebe, Stefan K G

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Laboratory Testing in Hyperthyroidism by Grebe, Stefan K.G., MD, PhD, Kahaly, George J., MD, PhD

“…Abstract The clinical diagnosis of hypo- or hyperthyroidism is difficult (full text available online: http://education.amjmed.com/pp1/272 ). Clinical symptoms…”
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The Roche Elecsys and Siemens-Centaur thyroglobulin autoantibody assays show comparable clinical performance to the recently unavailable Beckman-Coulter access thyroglobulin autoantibody assay in identifying samples with potentially false-low thyroglobulin measurements due to thyroglobulin autoantibody interference by Algeciras-Schimnich, Alicia, Lasho, Michael A, Ness, Karl M, Cheryk, Lynn A, Grebe, Stefan K G

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Evaluation of the PAX8/PPARG Translocation in Follicular Thyroid Cancer with a 4-Color Reverse-Transcription PCR Assay and Automated High-Resolution Fragment Analysis by Algeciras-Schimnich, Alicia, Milosevic, Dragana, McIver, Bryan, Flynn, Heather, Reddi, Honey V, Eberhardt, Norman L, Grebe, Stefan K.G

“…Molecular testing of thyroid malignancies, in combination with cytologic and histologic examination, is becoming increasingly attractive as a tool for refining…”
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Graves' Disease: Diagnostic and Therapeutic Challenges (Multimedia Activity) by Kahaly, George J., MD, PhD, Grebe, Stefan K.G., MD, PhD, Lupo, Mark A., MD, FACE, ECNU, McDonald, Nicole, MD, Sipos, Jennifer A., MD

“…Graves' disease is the most common cause of hyperthyroidism in the United States. Graves' disease occurs more often in women with a female:male ratio of 5:1…”
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Thyroid cancer nodal metastases: biologic significance and therapeutic considerations by Grebe, S K, Hay, I D

“…Lymph node metastases at presentation are common in PTC and MTC (about one third of patients at presentation), but are rare in other types of thyroid…”
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Increasing sample throughput on a standard 36-lane model 377 DNA sequencer to 48 or 64 samples per run by Velickovic, Z M, Velickovic, M B, Grebe, S K

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Chromosomal rearrangements and the pathogenesis of differentiated thyroid cancer by Honey V. Reddi, Alicia Algeciras-Schimnich, Bryan McIver, Norman L. Eberhardt, Stefan K.G. Grebe

“…The majority of thyroid cancers arise from the follicular cells of the thyroid gland, which yield a wide variety of distinct morphotypes, ranging from…”
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Commentary on Severe Hypokalaemia Associated with Paralysis after a Large Carbohydrate Intake following Exercise by Grebe, Stefan K G

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Chromosomal rearrangements and the pathogenesis of differentiated thyroid cancer by Honey V. Reddi, Alicia Algeciras-Schimnich, Bryan McIver, Norman L. Eberhardt, Stefan K.G. Grebe

“…The majority of thyroid cancers arise from the follicular cells of the thyroid gland, which yield a wide variety of distinct morphotypes, ranging from…”
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Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline by Lenders, Jacques W. M, Duh, Quan-Yang, Eisenhofer, Graeme, Gimenez-Roqueplo, Anne-Paule, Grebe, Stefan K. G, Murad, Mohammad Hassan, Naruse, Mitsuhide, Pacak, Karel, Young, William F

“…Objective: The aim was to formulate clinical practice guidelines for pheochromocytoma and paraganglioma (PPGL). Participants: The Task Force included a chair…”
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Clinical peptide and protein quantification by mass spectrometry (MS) by Grebe, Stefan K.G., Singh, Ravinder J.

“…•Quantitative mass spectrometry (MS) assays for peptides/proteins are more difficult to implement than low molecular weight MS assays.•Quantitative MS assays…”
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Overcoming the chromatographic challenges when performing LC-MS/MS measurements of pyridoxal-5′-phosphate by Maus, Anthony, Girtman, Adam, Kiesling, Jessa, Faber, Jennifer, Grebe, Stefan K.G.

“…•Developed and validated a unique method for high throughput measurements of Pyridoxal-5′-phosphate.•1-octanesulfonic acid improved the performance of LC-MS/MS…”
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Thyroglobulin (Tg) Testing Revisited: Tg Assays, TgAb Assays, and Correlation of Results With Clinical Outcomes by Netzel, Brian C, Grebe, Stefan K. G, Carranza Leon, B. Gisella, Castro, M. Regina, Clark, Penelope M, Hoofnagle, Andrew N, Spencer, Carole A, Turcu, Adina F, Algeciras-Schimnich, Alicia

“…Context: Measurement of thyroglobulin (Tg) by mass spectrometry (Tg-MS) is emerging as a tool for accurate Tg quantification in patients with anti-Tg…”
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LC-MS/MS in the Clinical Laboratory - Where to From Here? by Grebe, Stefan Kg, Singh, Ravinder J

“…Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has seen enormous growth in clinical laboratories during the last 10-15 years. It offers analytical…”
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Isotopic Distribution Calibration for Mass Spectrometry by Maus, Anthony D, Kemp, Jennifer V, Hoffmann, Todd J, Ramsay, Steven L, Grebe, Stefan K. G

“…Mass spectrometry (MS) is widely used in science and industry. It allows accurate, specific, sensitive, and reproducible detection and quantification of a huge…”
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Applying Standard Clinical Chemistry Assay Validation to Droplet Digital PCR Quantitative Liquid Biopsy Testing by Milosevic, Dragana, Mills, John R, Campion, Michael B, Vidal-Folch, Noemi, Voss, Jesse S, Halling, Kevin C, Highsmith, W Edward, Liu, Minetta C, Kipp, Benjamin R, Grebe, Stefan K G

“…Droplet digital PCR (ddPCR) is an emerging technology for quantitative cell-free DNA oncology applications. However, assay performance criteria must be…”
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First Steps toward Harmonization of LC-MS/MS Thyroglobulin Assays by Netzel, Brian C, Grant, Russell P, Hoofnagle, Andrew N, Rockwood, Alan L, Shuford, Christopher M, Grebe, Stefan K G

“…The variation in the observed slopes is likely explained by the different approach to calibration: ARUP and LabCorp use the calibration materials provided with…”
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