Search Results - "Greatrex, Ben"

Ring‐Expansion Reactions of the Biomass Derivative Cyrene via Enamine Dihalocyclopropanation by Puschnig, Johannes, Greatrex, Ben W.

“…A ring‐expansion process for the biomass derivative Cyrene obtained from levoglucosenone has been developed using gem‐dihalocyclopropanes as intermediates. The…”
Get full text

Intermolecular Enamine Mizoroki–Heck Reactions on a Bio-Derived Scaffold by Puschnig, Johannes, Jevric, Martyn, Sumby, Christopher J., Greatrex, Ben W.

“…The intramolecular enamine-Mizoroki–Heck reaction allows for the construction of nitrogen-containing heterocycles, although the related intermolecular version…”
Get full text

Intramolecular Proton-Coupled Hydride Transfers with Relatively Low Activation Barriers by Karton, Amir, Greatrex, Ben W., O’Reilly, Robert J.

“…We report that bifunctional molecules containing hydroxyl and carbonyl functional groups can undergo an effective transfer hydrogenation via an intramolecular…”
Get full text

Keeping it simple: lessons from the golden era of antibiotic discovery by Lyddiard, Dane, Jones, Graham L., Greatrex, Ben W.

“…Bacteria are becoming increasingly resistant to currently used antibiotics. At the same time, little progress has been made in discovering new antibacterial…”
Get full text

Support for a Dioxyallyl Cation in the Mechanism Leading to (−)-Levoglucosenone by Greatrex, Ben W, Meisner, Jan, Glover, Stephen A, Raverty, Warwick

“…Levoglucosenone (LGO) is the major product formed when cellulose is pyrolyzed in the presence of acid at temperatures between 170 and 350 °C. The current…”
Get full text

Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation by Wilson, Kirsty L, Kennedy, Alan R, Murray, Jane, Greatrex, Ben, Jamieson, Craig, Watson, Allan J B

“…Pd-catalysed C-C bond formation is an essential tool within the pharmaceutical and agrochemical industries. Many of these reactions rely heavily on polar…”
Get full text

Desymmetrization and Kinetic Resolution of Endoperoxides Using a Bifunctional Organocatalyst by Legendre, Sarah V. A.-M., Sumby, Christopher J., Karton, Amir, Greatrex, Ben W.

“…Bifunctional thiourea/amine organocatalysts have been used for the desymmetrization of meso-endoperoxides using the Kornblum–DeLaMare reaction, giving…”
Get full text

Skeletal rearrangement of 6,8-dioxabicyclo[3.2.1]octan-4-ols promoted by thionyl chloride or Appel conditions by Jevric, Martyn, Klepp, Julian, Puschnig, Johannes, Lamb, Oscar, Sumby, Christopher J, Greatrex, Ben W

“…A skeletal rearrangement of a series of 6,8-dioxabicyclo[3.2.1]octan-4-ols has been developed using SOCl in the presence of pyridine. An oxygen migration from…”
Get full text

Synthesis of enantiopure cyclopropyl esters from (-)-levoglucosenone by Stockton, Kieran P, Greatrex, Ben W

“…The biorenewable chiral synthon (-)-levoglucosenone has been converted to enantiopure cyclopropyl esters using the base-promoted carbocyclisation of…”
Get more information

Chemo-Enzymatic Synthesis of Chiral Epoxides Ethyl and Methyl (S)-3-(Oxiran-2-yl)propanoates from Renewable Levoglucosenone: An Access to Enantiopure (S)-Dairy Lactone by Peru, Aurélien A M, Flourat, Amandine L, Gunawan, Christian, Raverty, Warwick, Jevric, Martyn, Greatrex, Ben W, Allais, Florent

“…Chiral epoxides-such as ethyl and methyl (S)-3-(oxiran-2-yl)propanoates ((S)-1a/1b)-are valuable precursors in many chemical syntheses. Until recently, these…”
Get full text

Levoglucosenone: Bio-Based Platform for Drug Discovery by Camp, Jason E., Greatrex, Ben W.

“…Levoglucosone (LGO) is a bio-privileged molecule that can be produced on scale from waste biomass. This chiral building block has been converted via…”
Get full text

Bio‐Based Chiral Amines via Aza‐Michael Additions to (–)‐Levoglucosenone Under Aqueous Conditions by Kim, Shi‐Wei, Ledingham, Edward T., Kudo, Shinji, Greatrex, Ben W., Sperry, Jonathan

“…Chiral amines are highly coveted within the fine‐chemical industry and sustainable synthetic methodologies for their production are of great value. By…”
Get full text

Synthesis of allo- and epi-Inositol via the NHC-Catalyzed Carbocyclization of Carbohydrate-Derived Dialdehydes by Stockton, Kieran P, Greatrex, Ben W, Taylor, Dennis K

“…A synthesis of carbocyclic sugars from carbohydrate-derived dialdehydes using organocatalysis has been developed. Sorbitol, mannitol, and galactitol were…”
Get full text

Aziridination and aza-Wharton Reactions of Levoglucosenone by Ledingham, Edward T, Greatrex, Ben W

“…Efficient conditions have been developed for the diastereoselective aziridination of the biomass pyrolysis product (?)-levoglucosenone, via the reaction of…”
Get full text

Oxa-Michael-initiated cascade reactions of levoglucosenone by Klepp, Julian, Bousfield, Thomas, Cummins, Hugh, Legendre, Sarah V A-M, Camp, Jason E, Greatrex, Ben W

“…The reactions of aromatic aldehydes and levoglucosenone promoted by methoxide gives bridged α,β-unsaturated ketones, formed by a series of…”
Get full text

Composition and antimicrobial activity of the essential oils from the Phebalium squamulosum species complex (Rutaceae) in New South Wales, Australia by Sadgrove, Nicholas J., Telford, Ian R.H., Greatrex, Ben W., Jones, Graham L.

“…•Most subsp. of Phebalium squamulosum produce unique essential oils, qualifying as new chemotypes.•Chemotype variation complements work presently aimed at…”
Get full text

Biomimetic Synthesis of Mitchellenes B–H from the Abundant Biological Precursor 14-Hydroxy-6,12-muuroloadien-15-oic Acid by Klepp, Julian, Sadgrove, Nicholas J, Legendre, Sarah V. A.-M, Sumby, Christopher J, Greatrex, Ben W

“…A step-economic biomimetic synthesis of mitchellenes B–H found in Eremophila sturtii has been achieved. Starting from the putative muurolane biological…”
Get full text

Prostanthera (Lamiaceae) as a ‘Cradle of Incense’: Chemophenetics of Rare Essential Oils from Both New and Forgotten Australian ‘Mint Bush’ Species by Sadgrove, Nicholas J., Padilla-González, Guillermo F., Telford, Ian R. H., Greatrex, Ben W., Jones, Graham L., Andrew, Rose, Bruhl, Jeremy J., Langat, Moses K., Melnikovova, Ingrid, Fernandez-Cusimamani, Eloy

“…The highly aromatic Australian mint bushes from the genus Prostanthera Labill. produce a high yield of essential oil on hydrodistillation. Together with its…”
Get full text

New Labdanes with Antimicrobial and Acaricidal Activity: Terpenes of Callitris and Widdringtonia (Cupressaceae) by Sadgrove, Nicholas J, Senbill, Haytham, Van Wyk, Ben-Erik, Greatrex, Ben W

“…In spite of the evidence for antimicrobial and acaricidal effects in ethnobotanical reports of and , the diterpene acids from have never been described and no…”
Get full text

Diastereoselective Weitz-Scheffer epoxidation of levoglucosenone for the synthesis of isolevoglucosenone and derivatives by Ledingham, Edward T., Greatrex, Ben W.

“…High-yielding epoxidation conditions for the cellulose pyrolysis product (−)-levoglucosenone (LGO) and 3-aryl derivatives of LGO have been developed. The…”
Get full text