Search Results - "Grealy, Maura"
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Neuroprotective and Neuro-restorative Effects of Minocycline and Rasagiline in a Zebrafish 6-Hydroxydopamine Model of Parkinson’s Disease
Published in Neuroscience (26-12-2017)“…•3-day or 32-h 6-OHDA exposure induced locomotor deficit and neuronal loss in zebrafish larvae.•L-DOPA partially restored locomotor deficit but not neuronal…”
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Metabolic reprogramming and membrane glycan remodeling as potential drivers of zebrafish heart regeneration
Published in Communications biology (13-12-2022)“…The ability of the zebrafish heart to regenerate following injury makes it a valuable model to deduce why this capability in mammals is limited to early…”
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Identification of zygotic genes expressed at the midblastula transition in zebrafish
Published in Biochemical and biophysical research communications (29-06-2007)“…Early development of the embryo is directed by maternal gene products and characterised by limited zygotic gene activity, cell division synchrony and no cell…”
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A stereological study of developmental changes in hepatocyte ultrastructure of zebrafish (Danio rerio)
Published in Journal of anatomy (01-06-2020)“…Histopathology can reveal toxicant‐induced changes in the structure of a tissue or organ. A prerequisite for histopathological studies is a sound knowledge of…”
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Epidermal growth factor receptor and ligands in elongating bovine blastocysts
Published in Molecular reproduction and development (01-12-1998)“…Preimplantation development depends on multiple interactions between mother and embryo. The Epidermal Growth Factor Receptor (EGF‐R) and its ligands are…”
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Development of a seaweed derived platelet activating factor acetylhydrolase (PAF-AH) inhibitory hydrolysate, synthesis of inhibitory peptides and assessment of their toxicity using the Zebrafish larvae assay
Published in Peptides (New York, N.Y. : 1980) (01-12-2013)“…•Identification of a Palmaria palmata protein hydrolysate that inhibits PAF-AH.•This hydrolysate was non-toxic in a Zebrafish model when tested at 1mg/ml.•A…”
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Plakoglobin has both structural and signalling roles in zebrafish development
Published in Developmental biology (01-03-2009)“…Plakoglobin, or gamma-catenin, is found in both desmosomes and adherens junctions and participates in Wnt signalling. Mutations in the human gene are…”
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Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos
Published in The International journal of developmental biology (2010)“…The insulin-like growth factor (IGF) family is essential for normal embryonic growth and development and it is highly conserved through vertebrate evolution…”
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Loss of plakophilin 2 disrupts heart development in zebrafish
Published in The International journal of developmental biology (2012)“…The desmosomal armadillo protein plakophilin 2 is the only plakophilin expressed in the heart, and mutations in the human plakophilin 2 gene result in…”
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Molecular cloning and developmental expression of plakophilin 2 in zebrafish
Published in Biochemical and biophysical research communications (29-02-2008)“…Armadillo proteins are involved in providing strength and support to cells and tissues, nuclear transport, and transcriptional activation. In this report, we…”
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nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish
Published in Biochemical and biophysical research communications (05-08-2005)“…A novel, developmentally regulated gene, nanor, was identified by suppression subtractive hybridization. It is first expressed following the midblastula…”
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Cellular longevity: role of apoptosis and replicative senescence
Published in Biogerontology (Dordrecht) (01-01-2002)“…Cellular longevity refers to the lifespan of an individual cell. Normal cells have a finite lifespan and typically die by undergoing apoptosis, or enter into a…”
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09-P080 Effects of plakophilin 2 knockdown on zebrafish embryonic development
Published in Mechanisms of development (01-08-2009)Get full text
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Cyclin-dependent kinase 8 is expressed both maternally and zygotically during zebrafish embryo development
Published in Biochimica et biophysica acta (07-06-2002)“…Cyclin-dependent kinase 8 (cdk8) regulates transcription by phosphorylating RNA polymerase II and TFIIH. The mechanism of zygotic transcription activation…”
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Cyclic nucleotide and protein levels in preimplantation bovine embryos
Published in Biochemical Society transactions (01-02-1995)Get more information
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Royal Academy of Medicine in Ireland — Section of biological sciences Proceedings of Summer Meeting held on Thursday and Friday, 23rd and 24th June, 1988 Donegan Medal and Prize communications ( indicates competitor). The 1988 Donegan Medalist was E. Stuart, Department of Pharmacology, U.C.D
Published in Irish journal of medical science (01-11-1988)Get full text
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