Search Results - "Grbovic, Olivera M"
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1
Calpain activity regulates the cell surface distribution of amyloid precursor protein. Inhibition of calpains enhances endosomal generation of beta-cleaved C-terminal APP fragments
Published in The Journal of biological chemistry (27-09-2002)“…In murine L cells, treatment with calpeptin or calpain inhibitor III increased Abeta42, but not Abeta40, secretion in a dose-dependent fashion. This correlated…”
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Journal Article -
2
Calpain Activity Regulates the Cell Surface Distribution of Amyloid Precursor Protein
Published in The Journal of biological chemistry (27-09-2002)“…In murine L cells, treatment with calpeptin or calpain inhibitor III increased Aβ42, but not Aβ40, secretion in a dose-dependent fashion. This correlated with…”
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Journal Article -
3
Rab5-stimulated Up-regulation of the Endocytic Pathway Increases Intracellular β-Cleaved Amyloid Precursor Protein Carboxyl-terminal Fragment Levels and Aβ Production
Published in The Journal of biological chemistry (15-08-2003)“…We previously identified abnormalities of the endocytic pathway in neurons as the earliest known pathology in sporadic Alzheimer's disease (AD) and Down's…”
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4
Alzheimer's Disease-related Overexpression of the Cation-dependent Mannose 6-Phosphate Receptor Increases A beta Secretion: Role for altered lysosomal hydrolase distribution in beta -amyloidogenesis
Published in The Journal of biological chemistry (15-02-2002)“…Prominent endosomal and lysosomal changes are an invariant feature of neurons in sporadic Alzheimer's disease (AD). These changes include increased levels of…”
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Journal Article -
5
S5-02-03 Endosomal pathology in early stage Alzheimer's disease
Published in Neurobiology of aging (01-07-2004)Get full text
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6
Rab5-stimulated Up-regulation of the Endocytic Pathway Increases Intracellular β-Cleaved Amyloid Precursor Protein Carboxyl-terminal Fragment Levels and Aβ Production
Published in The Journal of biological chemistry (15-08-2003)“…We previously identified abnormalities of the endocytic pathway in neurons as the earliest known pathology in sporadic Alzheimer's disease (AD) and Down's…”
Get full text
Journal Article -
7
Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production
Published in The Journal of biological chemistry (15-08-2003)“…We previously identified abnormalities of the endocytic pathway in neurons as the earliest known pathology in sporadic Alzheimer's disease (AD) and Down's…”
Get full text
Journal Article -
8
Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis
Published in The Journal of biological chemistry (15-02-2002)“…Prominent endosomal and lysosomal changes are an invariant feature of neurons in sporadic Alzheimer's disease (AD). These changes include increased levels of…”
Get full text
Journal Article -
9
Alzheimer's Disease-related Overexpression of the Cation-dependent Mannose 6-Phosphate Receptor Increases Aβ Secretion
Published in The Journal of biological chemistry (15-02-2002)“…Prominent endosomal and lysosomal changes are an invariant feature of neurons in sporadic Alzheimer's disease (AD). These changes include increased levels of…”
Get full text
Journal Article -
10
Alzheimer's Disease-related Overexpression of the Cation-dependent Mannose 6-Phosphate Receptor Increases Aβ Secretion
Published in The Journal of biological chemistry (01-02-2002)Get full text
Journal Article