Search Results - "Graybiel, A.M."

ICCN2010-NL3 The basal ganglia and mind by Graybiel, A.M

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Optogenetic drive of neocortical pyramidal neurons generates fMRI signals that are correlated with spiking activity by Kahn, I, Knoblich, U, Desai, M, Bernstein, J, Graybiel, A.M, Boyden, E.S, Buckner, R.L, Moore, C.I

“…Abstract Local fluctuations in the blood oxygenation level-dependent (BOLD) signal serve as the basis of functional magnetic resonance imaging (fMRI)…”
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Identification and localization of a neuron-specific isoform of TAF1 in rat brain: implications for neuropathology of DYT3 dystonia by Sako, W, Morigaki, R, Kaji, R, Tooyama, I, Okita, S, Kitazato, K, Nagahiro, S, Graybiel, A.M, Goto, S

“…Abstract The neuron-specific isoform of the TAF1 gene ( N-TAF1 ) is thought to be involved in the pathogenesis of DYT3 dystonia, which leads to progressive…”
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Cortically Driven Immediate-Early Gene Expression Reflects Modular Influence of Sensorimotor Cortex on Identified Striatal Neurons in the Squirrel Monkey by Parthasarathy, H.B, Graybiel, A.M

“…Current understanding of basal ganglia function emphasizes their involvement in the focal, context-dependent release of motor and cognitive circuits in the…”
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Compartmental origins of striatal efferent projections in the cat by Jiménez-Castellanos, J, Graybiel, A M

“…Injections of the retrograde tracer, wheat germ agglutinated-horseradish peroxidase were placed in the substantia nigra, in adjoining dopamine-containing cell…”
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[3H]SCH 23390 binding to D1 dopamine receptors in the basal ganglia of the cat and primate: delineation of striosomal compartments and pallidal and nigral subdivisions by Besson, M J, Graybiel, A M, Nastuk, M A

“…The distribution of D1 dopamine receptors was studied autoradiographically in the basal ganglia of the cat, monkey and human. These receptor binding sites were…”
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Co-expression of neuropeptides in the cat's striatum: an immunohistochemical study of substance P, dynorphin B and enkephalin by Besson, M J, Graybiel, A M, Quinn, B

“…The expression of tachykinin-like and opioid-like peptides was studied in medium-sized neurons of the caudate nucleus in tissue from adult cats pretreated with…”
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Compartmental origins of the striatopallidal projection in the primate by Giménez-Amaya, J M, Graybiel, A M

“…The organization of striatopallidal projection neurons in the primate was studied by injecting horseradish peroxidase conjugated with wheat germ agglutinin and…”
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Location of saccade-related neurons in the macaque superior colliculus by MA, T. P, GRAYBIEL, A. M, WURTZ, R. H

“…The locations of saccade-related neurons were studied in the superior colliculi of two adult rhesus monkeys (Macaca mulatta) by placing marking lesions at the…”
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Characterization of substance P- and [Met]enkephalin-immunoreactive neurons in the caudate nucleus of cat and ferret by a single section Golgi procedure by Izzo, P N, Graybiel, A M, Bolam, J P

“…Modifications of the single-section Golgi-impregnation procedure of Gabbott and Somogyi are described. The modifications allow easier and more rapid…”
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Cellular substrate of the histochemically defined striosome/matrix system of the caudate nucleus: a combined Golgi and immunocytochemical study in cat and ferret by Bolam, J P, Izzo, P N, Graybiel, A M

“…In order to learn what morphological substrate might underly the histochemical compartments of the neostriatum, sections of the caudate nucleus and the putamen…”
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Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia by Sato, Kenta, Sumi-Ichinose, Chiho, Kaji, Ryuji, Ikemoto, Kazuhisa, Nomura, Takahide, Nagatsu, Ikuko, Ichinose, Hiroshi, Ito, Masayuki, Sako, Wataru, Nagahiro, Shinji, Graybiel, Ann M, Goto, Satoshi

“…Dopa-responsive dystonia (DRD) is a hereditary dystonia characterized by a childhood onset of fixed dystonic posture with a dramatic and sustained response to…”
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Complementary and non-matching afferent compartments in the cat's superior colliculus: innervation of the acetylcholinesterase-poor domain of the intermediate gray layer by Illing, R B, Graybiel, A M

“…Three tectal afferent-fiber systems were experimentally labeled in the cat to learn how their distributions within the superior colliculus were related to the…”
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Tetrode technology: advances in implantable hardware, neuroimaging, and data analysis techniques by Jog, M.S, Connolly, C.I, Kubota, Y, Iyengar, D.R, Garrido, L, Harlan, R, Graybiel, A.M

“…The technical advances in hardware and software for multiunit recordings have made it easier to gather data from a large number of neurons for behavioral…”
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CALDAG-GEFI-DEFICIENCY CAUSES IMPAIRED BETA1, BETA2, AND BETA3 INTEGRIN ACTIVATION IN NEUTROPHILS AND PLATELETS: A MODEL FOR LEUKOCYTE ADHESION DEFICIENCY-III (LAD-III) by Goerge, T., Bergmeier, W., Wang, H., Crittenden, J.R., Baldwin, A.C.W., Cifuni, S.M., Housman, D.E., Graybiel, A.M., Wagner, D.D.

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Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia by Holt, D.J., Herman, M.M., Hyde, T.M., Kleinman, J.E., Sinton, C.M., German, D.C., Hersh, L.B., Graybiel, A.M., Saper, C.B.

“…Neurochemical and functional abnormalities of the striatum have been reported in schizophrenic brains, but the cellular substrates of these changes are not…”
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Subdivisions of the dopamine-containing A8-A9-A10 complex identified by their differential mesostriatal innervation of striosomes and extrastriosomal matrix by Jimenez-Castellanos, J, Graybiel, A M

“…The mesostriatal projections from the dopamine-containing cells groups A8, A9 and A10 have been studied in the cat in relation to the histochemical…”
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Correspondence between the dopamine islands and striosomes of the mammalian striatum by Graybiel, A M

“…During the development of the mammalian striatum, the early-forming dopamine innervation is broken up into macroscopic patches called "dopamine islands". These…”
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Dopamine Uptake Sites in the Striatum are Distributed Differentially in Striosome and Matrix Compartments by Graybiel, Ann M., Moratalla, Rosario

“…A major mechanism of neurotransmitter inactivation at catecholaminergic synapses is reuptake of released transmitter at high-affinity uptake sites on…”
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Expression of the immediate early gene c-fos in basal ganglia: induction by dopaminergic drugs by Robertson, H A, Paul, M L, Moratalla, R, Graybiel, A M

“…Expression of the immediate early gene c-fos is increased in mammalian neurons by a number of stimuli and the usefulness of this gene as a marker of neuronal…”
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