Search Results - "Gray, Steve"
-
1
Effect of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial
Published in The Lancet (British edition) (13-12-2014)“…Summary Background Meningococcal conjugate vaccines protect individuals directly, but can also confer herd protection by interrupting carriage transmission. We…”
Get full text
Journal Article -
2
Genomic resolution of an aggressive, widespread, diverse and expanding meningococcal serogroup B, C and W lineage
Published in The Journal of infection (01-11-2015)“…Summary Objectives Neisseria meningitidis is a leading cause of meningitis and septicaemia. The hyperinvasive ST-11 clonal complex (cc11) caused serogroup C…”
Get full text
Journal Article -
3
Increase in penicillin-resistant invasive meningococcal serogroup W ST-11 complex isolates in England
Published in Vaccine (06-05-2021)“…Invasive meningococcal disease (IMD) caused by serogroup W meningococci belonging to the ST-11 complex (MenW:cc11) has been increasing globally since the early…”
Get full text
Journal Article -
4
Invasive meningococcal disease in patients with complement deficiencies: a case series (2008-2017)
Published in BMC infectious diseases (14-06-2019)“…To describe patients with inherited and acquired complement deficiency who developed invasive meningococcal disease (IMD) in England over the last decade…”
Get full text
Journal Article -
5
Tropical cyclone vance: 20 years on
Published in Australian journal of emergency management (01-07-2019)“…Tropical Cyclone Vance struck Exmouth on the Western Australia coast on 22 March 1999 causing widespread damage. What would happen if a similar cyclone struck…”
Get full text
Journal Article -
6
Outbreak strain characterisation and pharyngeal carriage detection following a protracted group B meningococcal outbreak in adolescents in South-West England
Published in Scientific reports (10-07-2019)“…Between April 2016 and September 2017, four cases of group B meningococcal disease were reported among sixth-form college students in Bristol, UK. Culture and…”
Get full text
Journal Article -
7
Meningococcal Group W Disease in Infants and Potential Prevention by Vaccination
Published in Emerging infectious diseases (01-08-2016)Get full text
Journal Article -
8
Preclinical biodistribution, tropism, and efficacy of oligotropic AAV/Olig001 in a mouse model of congenital white matter disease
Published in Molecular therapy. Methods & clinical development (12-03-2021)“…Recent advances in adeno-associated viral (AAV) capsid variants with novel oligotropism require validation in models of disease in order to be viable…”
Get full text
Journal Article -
9
Safe laboratory handling of Neisseria meningitidis
Published in The Journal of infection (01-04-2014)“…Summary Transmission of Neisseria meningitidis mainly occurs by formation of aerosols generated in the nasopharynx. Working with meningococci in vitro and…”
Get full text
Journal Article -
10
Frequent capsule switching in ‘ultra-virulent’ meningococci – Are we ready for a serogroup B ST-11 complex outbreak?
Published in The Journal of infection (01-08-2017)“…Summary The meningococcal ST-11 complex (cc11) causes large invasive disease outbreaks with high case fatality rates, such as serogroup C (MenC) epidemics in…”
Get full text
Journal Article -
11
Barriers and facilitators to adherence to group exercise in institutionalized older people living with dementia: a systematic review
Published in European review of aging and physical activity (09-11-2018)“…Research suggests targeted exercise is important for people living with dementia, especially those living in residential care. The aim of this review was to…”
Get full text
Journal Article -
12
Reduced turnaround time and improved diagnosis of invasive serogroup B Neisseria meningitidis and Streptococcus pneumoniae infections using a lyophilized quadruplex quantitative PCR
Published in Journal of medical microbiology (01-11-2015)“…Since 1996 the Meningococcal Reference Unit (MRU) in Manchester has provided a national service for PCR confirmation of meningococcal and pneumococcal disease…”
Get full text
Journal Article -
13
Colistin Sensitivity and Factor H-Binding Protein Expression among Commensal Neisseria Species
Published in mSphere (16-06-2021)“…Many bacterial carriage studies utilize colistin-containing media to select for Neisseria meningitidis among the diverse human pharyngeal milieu. These studies…”
Get full text
Journal Article -
14
‘Be on the TEAM’ Study (Teenagers Against Meningitis): protocol for a controlled clinical trial evaluating the impact of 4CMenB or MenB-fHbp vaccination on the pharyngeal carriage of meningococci in adolescents
Published in BMJ open (22-10-2020)“…IntroductionCapsular group B Neisseria meningitidis (MenB) is the most common cause of invasive meningococcal disease (IMD) in many parts of the world. A MenB…”
Get full text
Journal Article -
15
Epidemiological Evidence for the Role of the Hemoglobin Receptor, HmbR, in Meningococcal Virulence
Published in The Journal of infectious diseases (01-07-2009)“…The distribution of the hemoglobin receptor gene (hmbR) was investigated among disease and carriage Neisseria meningitidis isolates, revealing that the gene…”
Get full text
Journal Article -
16
An international invasive meningococcal disease outbreak due to a novel and rapidly expanding serogroup W strain, Scotland and Sweden, July to August 2015
Published in Euro surveillance : bulletin européen sur les maladies transmissibles (10-11-2016)“…The 23rd World Scout Jamboree in 2015 took place in Japan and included over 33,000 scouts from 162 countries. Within nine days of the meeting ending, six cases…”
Get full text
Journal Article -
17
Implications of differential age distribution of disease-associated meningococcal lineages for vaccine development
Published in Clinical and vaccine immunology (01-06-2014)“…New vaccines targeting meningococci expressing serogroup B polysaccharide have been developed, with some being licensed in Europe. Coverage depends on the…”
Get full text
Journal Article -
18
A prospective study of etiology of childhood acute bacterial meningitis, Turkey
Published in Emerging infectious diseases (01-07-2008)“…Determination of the etiology of bacterial meningitis and estimating cost of disease are important in guiding vaccination policies. To determine the incidence…”
Get full text
Journal Article -
19
W135 meningococcal disease in England and Wales associated with Hajj 2000 and 2001
Published in The Lancet (British edition) (16-02-2002)“…An outbreak of W135 meningococcal disease was seen in 2000 and 2001 among pilgrims returning from Saudi Arabia and their contacts. The Public Health Laboratory…”
Get full text
Journal Article -
20
Saliva and meningococcal transmission
Published in Emerging infectious diseases (01-10-2003)Get full text
Journal Article