Search Results - "Gray, Jeffrey L."

Neutron Reflectometry Studies of the Adsorbed Structure of the Amelogenin, LRAP by Tarasevich, Barbara J, Perez-Salas, Ursula, Masica, David L, Philo, John, Kienzle, Paul, Krueger, Susan, Majkrzak, Charles F, Gray, Jeffrey L, Shaw, Wendy J

“…Amelogenins make up over 90% of the protein present during enamel formation and have been demonstrated to be critical in proper enamel development, but the…”
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3-Aryl-2-(3'-substituted-1',2',4'-oxadiazol-5'-yl)tropane analogs of cocaine: affinities at the cocaine binding site at the dopamine, serotonin, and norepinephrine transporters by Carroll, F. Ivy, Gray, Jeffrey L, Abraham, Philip, Kuzemko, Michael A, Lewin, Anita H, Boja, John W, Kuhar, Michael J

“…Previous studies have shown that 3 beta-(substituted phenyl)tropan-2 beta-carboxylic acid esters possess high affinity for the cocaine binding site on the…”
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1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors by Klopfenstein, Sean R., Evdokimov, Artem G., Colson, Anny-Odile, Fairweather, Neil T., Neuman, Jeffrey J., Maier, Matthew B., Gray, Jeffrey L., Gerwe, Gina S., Stake, George E., Howard, Brian W., Farmer, Julie A., Pokross, Matthew E., Downs, Thomas R., Kasibhatla, Bhavani, Peters, Kevin G.

“…High-throughput screening of the P&GP corporate repository against several protein tyrosine phosphatases identified the sulfamic acid moiety as potential…”
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Design and synthesis of potent, non-peptidic inhibitors of HPTPβ by Amarasinghe, Kande K.D., Evidokimov, Artem G., Xu, Kevin, Clark, Cynthia M., Maier, Matthew B., Srivastava, Anil, Colson, Anny-Odile, Gerwe, Gina S., Stake, George E., Howard, Brian W., Pokross, Matthew E., Gray, Jeffrey L., Peters, Kevin G.

“…The sulfamic acid phosphotyrosine mimetic was coupled with a previously known malonate template to obtain highly selective and potent inhibitors of HPTPβ…”
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Discovery of (3S)-Amino-(4R)-ethylpiperidinyl Quinolones as Potent Antibacterial Agents with a Broad Spectrum of Activity and Activity against Resistant Pathogens by Hu, X. Eric, Kim, Nick K, Gray, Jeffrey L, Almstead, Ji-In K, Seibel, William L, Ledoussal, Benoit

“…Novel quinolone antibacterial agents bearing (3S)-amino-(4R)-ethylpiperidines were designed by using low energy conformation analysis and synthesized by…”
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Synthesis and biological testing of non-Fluorinated analogues of levofloxacin by Gray, Jeffrey L., Almstead, Ji-In K., Gallagher, Corey P., Hu, X.Eric, Kim, Nick K., Taylor, Cynthia J., Twinem, Tracy L., Wallace, Cynthia D., Ledoussal, Benoit

“…Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the…”
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Synthetic studies on the ginkgolides: total synthesis of (.+-.)-bilobalide by Crimmins, Michael T, Jung, David K, Gray, Jeffrey L

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One-pot synthesis of 1,2,4-oxadiazoles from carboxylic acid esters and amidoximes using potassium carbonate by Amarasinghe, Kande K.D., Maier, Matthew B., Srivastava, Anil, Gray, Jeffrey L.

“…A convenient one-pot synthesis of 1,2,4-oxadiazoles is described. The condensation of carboxylic acid esters and amidoximes in the presence of potassium…”
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A total synthesis of (.+-.)-bilobalide by Crimmins, Michael T, Jung, David K, Gray, Jeffrey L

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Cocaine and 3.beta.-(4'-Substituted phenyl)tropane-2.beta.-carboxylic Acid Ester and Amide Analogs. New High-Affinity and Selective Compounds for the Dopamine Transporter by Carroll, F. Ivy, Kotian, Pravin, Dehghani, Ali, Gray, Jeffrey L, Kuzemko, Michael A, Parham, Karol A, Abraham, Philip, Lewin, Anita H, Boja, John W, Kuhar, Michael J

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Corrigendum to “Design and synthesis of potent, non-peptidic inhibitors of HPTPβ” [Bioorg. Med. Chem. Lett. 16 (2006) 4252–4256] by Amarasinghe, Kande K.D., Evdokimov, Artem G., Xu, Kevin, Clark, Cynthia M., Maier, Matthew B., Srivastava, Anil, Colson, Anny-Odile, Gerwe, Gina S., Stake, George E., Howard, Brian W., Pokross, Matthew E., Gray, Jeffrey L., Peters, Kevin G.

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Cocaine and 3β-(4'-substituted phenyl)tropane-2β-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter by CARROLL, F. I, KOTIAN, P, ALI DEHGHANI, GRAY, J. L, KUZEMKO, M. A, PARHAM, K. A, ABRAHAM, P, LEWIN, A. H, BOJA, J. W, KUHAR, M. J

“…Several 2 beta-carboxylic acid ester and amide analogues of cocaine and of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid were prepared. The…”
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Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta by Amarasinghe, Kande K D, Evdokimov, Artem G, Evidokimov, Artem G, Xu, Kevin, Clark, Cynthia M, Maier, Matthew B, Srivastava, Anil, Colson, Anny-Odile, Gerwe, Gina S, Stake, George E, Howard, Brian W, Pokross, Matthew E, Gray, Jeffrey L, Peters, Kevin G

“…The sulfamic acid phosphotyrosine mimetic was coupled with a previously known malonate template to obtain highly selective and potent inhibitors of HPTPbeta…”
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Addition of zinc homoenolates to acetylenic esters and amides: a formal [3 + 2] cycloaddition by Crimmins, Michael T, Nantermet, Philippe G, Trotter, B. Wesley, Vallin, Isabelle M, Watson, Paul S, McKerlie, Lynne A, Reinhold, Tracy L, Cheung, Adrian Wai Hing, Stetson, Katherine A

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