Search Results - "Gray, Elin S"

Liquid biopsy in ovarian cancer using circulating tumor DNA and cells: Ready for prime time? by Asante, Du-Bois, Calapre, Leslie, Ziman, Melanie, Meniawy, Tarek M., Gray, Elin S.

“…Liquid biopsies hold the potential to inform cancer patient prognosis and to guide treatment decisions at the time when direct tumor biopsy may be impractical…”
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Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes by Wibmer, Constantinos Kurt, Bhiman, Jinal N, Gray, Elin S, Tumba, Nancy, Abdool Karim, Salim S, Williamson, Carolyn, Morris, Lynn, Moore, Penny L

“…Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to…”
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Identification of TP53 mutations in circulating tumour DNA in high grade serous ovarian carcinoma using next generation sequencing technologies by Calapre, Leslie, Giardina, Tindaro, Beasley, Aaron B., Reid, Anna L., Stewart, Colin, Amanuel, Benhur, Meniawy, Tarek M., Gray, Elin S.

“…Plasma circulating tumour DNA (ctDNA) has been suggested to be a viable biomarker of response to treatment in patients with high grade serous ovarian carcinoma…”
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The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection by GRAY, Elin S, MADIGA, Maphuti C, ABDOOL KARIM, Salim S, MORRIS, Lynn, HERMANUS, Tandile, MOORE, Penny L, WIBMER, Constantinos Kurt, TUMBA, Nancy L, WERNER, Lise, MLISANA, Koleka, SIBEKO, Sengeziwe, WILLIAMSON, Carolyn

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Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients by McEvoy, Ashleigh C, Warburton, Lydia, Al-Ogaili, Zeyad, Celliers, Liesl, Calapre, Leslie, Pereira, Michelle R, Khattak, Muhammad A, Meniawy, Tarek M, Millward, Michael, Ziman, Melanie, Gray, Elin S

“…Circulating tumour DNA (ctDNA) may serve as a measure of tumour burden and a useful tool for non-invasive monitoring of cancer. However, ctDNA is not always…”
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Tumour PD-L1 Expression in Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis by Acheampong, Emmanuel, Abed, Afaf, Morici, Michael, Bowyer, Samantha, Amanuel, Benhur, Lin, Weitao, Millward, Michael, Gray, Elin S

“…Antibodies against programmed death-1 (PD-1), and its ligand, (PD-L1) have been approved recently for the treatment of small-cell lung cancer (SCLC). Although…”
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Evolution of an HIV glycan–dependent broadly neutralizing antibody epitope through immune escape by Moore, Penny L, Gray, Elin S, Wibmer, C Kurt, Bhiman, Jinal N, Nonyane, Molati, Sheward, Daniel J, Hermanus, Tandile, Bajimaya, Shringkhala, Tumba, Nancy L, Abrahams, Melissa-Rose, Lambson, Bronwen E, Ranchobe, Nthabeleng, Ping, Lihua, Ngandu, Nobubelo, Karim, Quarraisha Abdool, Karim, Salim S Abdool, Swanstrom, Ronald I, Seaman, Michael S, Williamson, Carolyn, Morris, Lynn

“…A minority of HIV-1–infected individuals develop broadly neutralizing antibodies, which are considered an important goal of many HIV vaccine strategies. Moore…”
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Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting by Morris, Lynn, Chen, Xi, Alam, Munir, Tomaras, Georgia, Zhang, Ruijun, Marshall, Dawn J, Chen, Bing, Parks, Robert, Foulger, Andrew, Jaeger, Frederick, Donathan, Michele, Bilska, Mira, Gray, Elin S, Abdool Karim, Salim S, Kepler, Thomas B, Whitesides, John, Montefiori, David, Moody, M Anthony, Liao, Hua-Xin, Haynes, Barton F

“…Broadly neutralizing antibodies are not commonly produced in HIV-1 infected individuals nor by experimental HIV-1 vaccines. When these antibodies do occur, it…”
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Enhancing circulatory myokines and extracellular vesicle uptake with targeted exercise in patients with prostate cancer (the MYEX trial): a single-group crossover study by Kim, Jin-Soo, Taaffe, Dennis R, Galvão, Daniel A, Clay, Timothy D, Redfern, Andrew D, Gray, Elin S, Newton, Robert U

“…Physical activity is associated with improved disease progression and cancer-specific survival in patients with prostate cancer (PCa). However, the mechanisms…”
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Circulating tumour DNA (ctDNA) as a biomarker in metachronous melanoma and colorectal cancer- a case report by Calapre, Leslie, Warburton, Lydia, Millward, Michael, Gray, Elin S

“…Circulating tumour DNA (ctDNA) has emerged as a promising blood-based biomarker for monitoring disease status of patients with advanced cancers. The presence…”
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Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies by Scheepers, Cathrine, Kgagudi, Prudence, Mzindle, Nonkululeko, Gray, Elin S, Moyo-Gwete, Thandeka, Lambson, Bronwen E, Oosthuysen, Brent, Mabvakure, Batsirai, Garrett, Nigel J, Abdool Karim, Salim S, Morris, Lynn, Moore, Penny L

“…Broadly neutralizing antibodies (bNAbs) that target the membrane-proximal external region (MPER) of HIV gp41 envelope, such as 4E10, VRC42.01 and PGZL1, can…”
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Genetic analysis of heterogeneous subsets of circulating tumour cells from high grade serous ovarian carcinoma patients by Asante, Du-Bois, Mohan, Ganendra R. K. A., Acheampong, Emmanuel, Ziman, Melanie, Calapre, Leslie, Meniawy, Tarek M., Gray, Elin S., Beasley, Aaron B.

“…Circulating tumour cells (CTCs) are heterogenous and contain genetic information from the tumour of origin. They bear specific intra- and extra-cellular…”
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Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals by TOMARAS, Georgia D, BINLEY, James M, DECKER, Julie, WIBMER, Constantinos Kurt, FENG GAO, ALAM, S. Munir, EASTERBROOK, Philippa, KARIM, Salim Abdool, KAMANGA, Gift, CRUMP, John A, COHEN, Myron, SHAW, George M, GRAY, Elin S, MASCOLA, John R, HAYNES, Barton F, MONTEFIORI, David C, MORRIS, Lynn, CROOKS, Emma T, OSAWA, Keiko, MOORE, Penny L, TUMBA, Nancy, TONG, Tommy, XIAOYING SHEN, YATES, Nicole L

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Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones by Denisenko, Elena, de Kock, Leanne, Tan, Adeline, Beasley, Aaron B., Beilin, Maria, Jones, Matthew E., Hou, Rui, Muirí, Dáithí Ó, Bilic, Sanela, Mohan, G. Raj K. A., Salfinger, Stuart, Fox, Simon, Hmon, Khaing P. W., Yeow, Yen, Kim, Youngmi, John, Rhea, Gilderman, Tami S., Killingbeck, Emily, Gray, Elin S., Cohen, Paul A., Yu, Yu, Forrest, Alistair R. R.

“…High-grade serous ovarian carcinoma (HGSOC) is genetically unstable and characterised by the presence of subclones with distinct genotypes. Intratumoural…”
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Potent and Broad Neutralization of HIV-1 Subtype C by Plasma Antibodies Targeting a Quaternary Epitope Including Residues in the V2 Loop by MOORE, Penny L, GRAY, Elin S, SIBEKO, Sengeziwe, MLISANA, Koleka, ABDOOL KARIM, Salim S, WILLIAMSON, Carolyn, PINTER, Abraham, MORRIS, Lynn, SHEWARD, Daniel, MADIGA, Maphuti, RANCHOBE, Nthabeleng, ZHONG LAI, HONNEN, William J, NONYANE, Molati, TUMBA, Nancy, HERMANUS, Tandile

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Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection by Moore, Penny L, Ranchobe, Nthabeleng, Lambson, Bronwen E, Gray, Elin S, Cave, Eleanor, Abrahams, Melissa-Rose, Bandawe, Gama, Mlisana, Koleka, Abdool Karim, Salim S, Williamson, Carolyn, Morris, Lynn

“…We previously showed that HIV-1 subtype C viruses elicit potent but highly type-specific neutralizing antibodies (nAb) within the first year of infection. In…”
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The Development of CD4 Binding Site Antibodies during HIV-1 Infection by LYNCH, Rebecca M, TRAN, Lillian, MONTEFIORI, David C, SIBEKO, Sengeziwe, SODERBERG, Kelly, TOMARAS, Georgia, YANG, Zhi-Yong, NABEL, Gary J, SCHUITEMAKER, Hanneke, MORRIS, Lynn, HAYNES, Barton F, MASCOLA, John R, LOUDER, Mark K, SCHMIDT, Stephen D, COHEN, Myron, DERSIMONIAN, Rebecca, EULER, Zelda, GRAY, Elin S, ABDOOL KARIM, Salim, KIRCHHERR, Jennifer

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Locus‐specific concordance of genomic alterations between tissue and plasma circulating tumor DNA in metastatic melanoma by Calapre, Leslie, Giardina, Tindaro, Robinson, Cleo, Reid, Anna L., Al‐Ogaili, Zeyad, Pereira, Michelle R., McEvoy, Ashleigh C., Warburton, Lydia, Hayward, Nicholas K., Khattak, Muhammad A., Meniawy, Tarek M., Millward, Michael, Amanuel, Benhur, Ziman, Melanie, Gray, Elin S.

“…Circulating tumor DNA (ctDNA) may serve as a surrogate to tissue biopsy for noninvasive identification of mutations across multiple genetic loci and for…”
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Multiple Pathways of Escape from HIV Broadly Cross-Neutralizing V2-Dependent Antibodies by Moore, Penny L, Sheward, Daniel, Nonyane, Molati, Ranchobe, Nthabeleng, Hermanus, Tandile, Gray, Elin S, Abdool Karim, Salim S, Williamson, Carolyn, Morris, Lynn

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Antibody Specificities Associated with Neutralization Breadth in Plasma from Human Immunodeficiency Virus Type 1 Subtype C-Infected Blood Donors by GRAY, Elin S, TAYLOR, Natasha, MONTEFIORI, David C, BINLEY, James M, SHAW, George M, HAYNES, Barton F, MASCOLA, John R, MORRIS, Lynn, WYCUFF, Diane, MOORE, Penny L, TOMARAS, Georgia D, KURT WIBMER, Constantinos, PUREN, Adrian, DECAMP, Allan, GILBERT, Peter B, WOOD, Blake

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