Search Results - "Gray, A. M."
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UKPDS Outcomes Model 2: a new version of a model to simulate lifetime health outcomes of patients with type 2 diabetes mellitus using data from the 30 year United Kingdom Prospective Diabetes Study: UKPDS 82
Published in Diabetologia (01-09-2013)“…Aims/hypothesis The aim of this project was to build a new version of the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS-OM1), a…”
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The impact of social isolation on delayed hospital discharges of older hip fracture patients and associated costs
Published in Osteoporosis international (01-02-2016)“…Summary Delayed discharges represent an inefficient use of acute hospital beds. Social isolation and referral to a public-funded rehabilitation unit were…”
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Prefrontal activity in Huntington's disease reflects cognitive and neuropsychiatric disturbances: The IMAGE-HD study
Published in Experimental neurology (01-01-2013)“…Functional integrity of prefrontal cortico-striatal circuits underlying executive functioning may be compromised by basal ganglia degeneration during…”
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A model to estimate the lifetime health outcomes of patients with Type 2 diabetes: the United kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS no. 68)
Published in Diabetologia (01-10-2004)“…The aim of this study was to develop a simulation model for type 2 diabetes that can be used to estimate the likely occurrence of major diabetes-related…”
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Autism Attenuates Sex Differences in Brain Structure: A Combined Voxel-Based Morphometry and Diffusion Tensor Imaging Study
Published in American journal of neuroradiology : AJNR (01-01-2012)“…It has been proposed that autism spectrums condition may represent a form of extreme male brain (EMB), a notion supported by psychometric, behavioral, and…”
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Ethanol and its non-oxidative metabolites profoundly inhibit CFTR function in pancreatic epithelial cells which is prevented by ATP supplementation
Published in Pflügers Archiv (01-03-2014)“…Excessive alcohol consumption is a major cause of acute pancreatitis, but the mechanism involved is not well understood. Recent investigations suggest that…”
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An investigation into the performance of the Adjuvant! Online prognostic programme in early breast cancer for a cohort of patients in the United Kingdom
Published in British journal of cancer (06-10-2009)“…Background: Adjuvant! Online is an internet-based computer programme providing 10-year prognosis predictions for early breast cancer patients. It was developed…”
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Cost-utility analyses of intensive blood glucose and tight blood pressure control in type 2 diabetes (UKPDS 72)
Published in Diabetologia (01-05-2005)“…This study estimated the economic efficiency (1) of intensive blood glucose control and tight blood pressure control in patients with type 2 diabetes who also…”
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Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig
Published in Gut (01-08-2008)“…Acute pancreatitis is associated with significant morbidity and mortality. Bile reflux into the pancreas is a common cause of acute pancreatitis and, although…”
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Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma
Published in Leukemia (01-09-2010)“…Antibody-drug conjugates (ADCs) are potent cytotoxic drugs linked to antibodies through chemical linkers, and allow specific targeting of drugs to neoplastic…”
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The cost-effectiveness of adjuvant chemotherapy for early breast cancer: A comparison of no chemotherapy and first, second, and third generation regimens for patients with differing prognoses
Published in European journal of cancer (1990) (01-11-2011)“…Abstract Background The risk of recurrence following surgery in women with early breast cancer varies, depending upon prognostic factors. Adjuvant chemotherapy…”
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Estimation and external validation of a new prognostic model for predicting recurrence-free survival for early breast cancer patients in the UK
Published in British journal of cancer (07-09-2010)“…Background: We aimed to estimate and externally validate a new UK-specific prognostic model for predicting the long-term risk of a first recurrent event (local…”
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Impact of hip fracture on hospital care costs: a population-based study
Published in Osteoporosis international (01-02-2016)“…Summary Using a large cohort of hip fracture patients, we estimated hospital costs to be £14,163 and £2139 in the first and second year following fracture,…”
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Gray matter textural heterogeneity as a potential in-vivo biomarker of fine structural abnormalities in Asperger syndrome
Published in The pharmacogenomics journal (01-02-2013)“…Brain imaging studies contribute to the neurobiological understanding of Autism Spectrum Conditions (ASC). Herein, we tested the prediction that distributed…”
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Sendai virus-mediated CFTR gene transfer to the airway epithelium
Published in Gene therapy (01-10-2007)“…The potential for gene therapy to be an effective treatment for cystic fibrosis has been hampered by the limited gene transfer efficiency of current vectors…”
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Using stable isotope analysis with telemetry or mark-recapture data to identify fish movement and foraging
Published in Oecologia (01-08-2005)“…Information about animal movements has often been inferred from stable isotope analysis (SIA), but is dependent on animals assimilating site-specific isotopic…”
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The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds
Published in British journal of pharmacology (01-06-1998)“…Debate exists as to the nature of antidepressant‐induced antinociception. It is unclear whether antidepressants are inherently antinociceptive, are able to…”
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Insulin-releasing and insulin-like activity of Agaricus campestris (mushroom)
Published in Journal of endocrinology (01-05-1998)“…Agaricus campestris (mushroom) has been documented as a traditional treatment for diabetes. Here the administration of mushroom in the diet (62.5 g/kg) and…”
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Insulin-secreting activity of the traditional antidiabetic plant Viscum album (mistletoe)
Published in Journal of endocrinology (01-03-1999)“…Viscum album (mistletoe) has been documented as a traditional treatment of diabetes. In acute 20-min tests, 1-10 mg/ml aqueous extract of mistletoe evoked a…”
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Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander)
Published in British journal of nutrition (01-03-1999)“…Coriandrum sativum (coriander) has been documented as a traditional treatment of diabetes. In the present study, coriander incorporated into the diet (62·5…”
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