Search Results - "Gravning, Jørgen"

Revisiting the obesity paradox in heart failure: Per cent body fat as predictor of biomarkers and outcome by Aimo, Alberto, Januzzi, James L, Vergaro, Giuseppe, Clerico, Aldo, Latini, Roberto, Meessen, Jennifer, Anand, Inder S, Cohn, Jay N, Gravning, Jørgen, Ueland, Thor, Nymo, Ståle H, Brunner-La Rocca, Hans-Peter, Bayes-Genis, Antoni, Lupón, Josep, de Boer, Rudolf A, Yoshihisa, Akiomi, Takeishi, Yasuchika, Egstrup, Michael, Gustafsson, Ida, Gaggin, Hanna K, Eggers, Kai M, Huber, Kurt, Tentzeris, Ioannis, Ripoli, Andrea, Passino, Claudio, Emdin, Michele

“…Aims Obesity defined by body mass index (BMI) is characterized by better prognosis and lower plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) in…”
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Re-appraisal of the obesity paradox in heart failure: a meta-analysis of individual data by Marcks, Nick, Aimo, Alberto, Januzzi, James L., Vergaro, Giuseppe, Clerico, Aldo, Latini, Roberto, Meessen, Jennifer, Anand, Inder S., Cohn, Jay N., Gravning, Jørgen, Ueland, Thor, Bayes-Genis, Antoni, Lupón, Josep, de Boer, Rudolf A., Yoshihisa, Akiomi, Takeishi, Yasuchika, Egstrup, Michael, Gustafsson, Ida, Gaggin, Hanna K., Eggers, Kai M., Huber, Kurt, Tentzeris, Ioannis, Ripoli, Andrea, Passino, Claudio, Sanders-van Wijk, Sandra, Emdin, Michele, Brunner-La Rocca, Hans-Peter

“…Background Higher body mass index (BMI) is associated with better outcome compared with normal weight in patients with HF and other chronic diseases. It…”
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CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload by Gravning, Jørgen, Ahmed, Mohammed Shakil, von Lueder, Thomas G, Edvardsen, Thor, Attramadal, Håvard

“…Abstract Background Myocardial CCN2/CTGF (connective tissue growth factor) is strongly induced in heart failure (HF) and acts as a cardioprotective factor in…”
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Mechanical dispersion as a marker of left ventricular dysfunction and prognosis in stable coronary artery disease by Kvisvik, Brede, Aagaard, Erika Nerdrum, Mørkrid, Lars, Røsjø, Helge, Lyngbakken, Magnus, Smedsrud, Marit Kristine, Eek, Christian, Bendz, Bjørn, Haugaa, Kristina H., Edvardsen, Thor, Gravning, Jørgen

“…Assessment of global longitudinal strain (GLS) is superior to ejection fraction (EF) in the evaluation of left ventricular (LV) function in patients with…”
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Gene therapy with hypoxia-inducible factor 1 alpha in skeletal muscle is cardioprotective in vivo by Czibik, Gabor, Gravning, Jørgen, Martinov, Vladimir, Ishaq, Bushra, Knudsen, Eirunn, Attramadal, Håvard, Valen, Guro

“…Gene therapy of a peripheral organ to protect the heart is clinically attractive. The transcription factor hypoxia-inducible factor 1 alpha (HIF-1α)…”
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The perfect biomarker in acute coronary syndrome: a challenge for diagnosis, prognosis, and treatment by Gravning, Jørgen, Kjekshus, John

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Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors by Bergestuen, Deidi Strickland, Gravning, Jørgen, Haugaa, Kristina Hermann, Sahakyan, Laura G, Aakhus, Svend, Thiis-Evensen, Espen, Øie, Erik, Aukrust, Pål, Attramadal, Håvard, Edvardsen, Thor

“…Carcinoid heart disease, a known complication of neuroendocrine tumors, is characterized by right heart fibrotic lesions. Carcinoid heart disease has…”
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Cardiac-restricted Expression of the Carboxyl-terminal Fragment of GRK3 Uncovers Distinct Functions of GRK3 in Regulation of Cardiac Contractility and Growth: GRK3 CONTROLS CARDIAC α₁-ADRENERGIC RECEPTOR RESPONSIVENESS by Vinge, Leif Erik, von Lueder, Thomas G, Aasum, Ellen, Qvigstad, Eirik, Gravning, Jørgen A, How, Ole-Jakob, Edvardsen, Thor, Bjørnerheim, Reidar, Ahmed, M. Shakil, Mikkelsen, Birthe W, Øie, Erik, Attramadal, Toril, Skomedal, Tor, Smiseth, Otto A, Koch, Walter J, Larsen, Terje S, Attramadal, Håvard

“…G protein-coupled receptor kinase-2 and -3 (GRK2 and GRK3) in cardiac myocytes catalyze phosphorylation and desensitization of different G protein-coupled…”
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Prognostic Value of High-Sensitivity Troponin T in Chronic Heart Failure: An Individual Patient Data Meta-Analysis by Aimo, Alberto, Januzzi, Jr, James L, Vergaro, Giuseppe, Ripoli, Andrea, Latini, Roberto, Masson, Serge, Magnoli, Michela, Anand, Inder S, Cohn, Jay N, Tavazzi, Luigi, Tognoni, Gianni, Gravning, Jørgen, Ueland, Thor, Nymo, Ståle H, Brunner-La Rocca, Hans-Peter, Bayes-Genis, Antoni, Lupón, Josep, de Boer, Rudolf A, Yoshihisa, Akiomi, Takeishi, Yasuchika, Egstrup, Michael, Gustafsson, Ida, Gaggin, Hanna K, Eggers, Kai M, Huber, Kurt, Tentzeris, Ioannis, Tang, Wai H W, Grodin, Justin, Passino, Claudio, Emdin, Michele

“…Most patients with chronic heart failure have detectable troponin concentrations when evaluated by high-sensitivity assays. The prognostic relevance of this…”
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High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis by Kvisvik, Brede, Mørkrid, Lars, Røsjø, Helge, Cvancarova, Milada, Rowe, Alexander D, Eek, Christian, Bendz, Bjørn, Edvardsen, Thor, Gravning, Jørgen

“…High-sensitivity cardiac troponin (hs-cTn) T and I assays are established as crucial tools for the diagnosis of acute myocardial infarction (AMI), as they have…”
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Different prognostic importance of elevated troponin I after percutaneous coronary intervention in acute coronary syndrome and stable angina pectoris by Gravning, Jørgen, Ueland, Thor, Mørkrid, Lars, Endresen, Knut, Aaberge, Lars, Kjekshus, John

“…To investigate the prognostic importance of cardiac troponin I (cTnI) elevation after percutaneous coronary intervention (PCI) in different clinical settings…”
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Myocardial connective tissue growth factor (CCN2/CTGF) attenuates left ventricular remodeling after myocardial infarction by Gravning, Jørgen, Ørn, Stein, Kaasbøll, Ole Jørgen, Martinov, Vladimir N, Manhenke, Cord, Dickstein, Kenneth, Edvardsen, Thor, Attramadal, Håvard, Ahmed, Mohammed Shakil

“…Myocardial CCN2/CTGF is induced in heart failure of various etiologies. However, its role in the pathophysiology of left ventricular (LV) remodeling after…”
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Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury by Ahmed, M Shakil, Gravning, Jørgen, Martinov, Vladimir N, von Lueder, Thomas G, Edvardsen, Thor, Czibik, Gabor, Moe, Ingvild T, Vinge, Leif E, Øie, Erik, Valen, Guro, Attramadal, Håvard

“…CCN2/connective tissue growth factor (CTGF), a CCN family matricellular protein repressed in healthy hearts after birth, is induced in heart failure of various…”
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High-sensitivity troponin T, NT-proBNP and glomerular filtration rate: A multimarker strategy for risk stratification in chronic heart failure by Aimo, Alberto, Januzzi, James L., Vergaro, Giuseppe, Ripoli, Andrea, Latini, Roberto, Masson, Serge, Magnoli, Michela, Anand, Inder S., Cohn, Jay N., Tavazzi, Luigi, Tognoni, Gianni, Gravning, Jørgen, Ueland, Thor, Nymo, Ståle H., Rocca, Hans-Peter Brunner-La, Bayes-Genis, Antoni, Lupón, Josep, de Boer, Rudolf A., Yoshihisa, Akiomi, Takeishi, Yasuchika, Egstrup, Michael, Gustafsson, Ida, Gaggin, Hanna K., Eggers, Kai M., Huber, Kurt, Tentzeris, Ioannis, Wilson Tang, W.H., Grodin, Justin L., Passino, Claudio, Emdin, Michele

“…In a recent individual patient data meta-analysis, high-sensitivity troponin T (hs-TnT) emerged as robust predictor of prognosis in stable chronic heart…”
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Prognostic effect of high-sensitive troponin T assessment in elderly patients with chronic heart failure: results from the CORONA trial by Gravning, Jørgen, Askevold, Erik T, Nymo, Ståle H, Ueland, Thor, Wikstrand, John, McMurray, John J V, Aukrust, Pål, Gullestad, Lars, Kjekshus, John

“…The incremental prognostic value of high-sensitive troponin T (hs-cTnT) in heart failure (HF) beyond that of high-sensitivity C-reactive protein and…”
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Sensitive troponin assays and N-terminal pro–B-type natriuretic peptide in acute coronary syndrome: Prediction of significant coronary lesions and long-term prognosis by Gravning, Jørgen, MD, Smedsrud, Marit Kristine, MD, Omland, Torbjørn, MD, PhD, Eek, Christian, MD, PhD, Skulstad, Helge, MD, PhD, Aaberge, Lars, MD, PhD, Bendz, Bjørn, MD, PhD, Kjekshus, John, MD, PhD, Mørkrid, Lars, MD, PhD, Edvardsen, Thor, MD, PhD, FESC

“…Background Sensitive troponin assays have substantially improved early diagnosis of myocardial infarction. However, the role of sensitive cardiac troponin…”
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Limited Added Value of Circulating Inflammatory Biomarkers in Chronic Heart Failure by Nymo, Ståle H., MD, Aukrust, Pål, MD, PhD, Kjekshus, John, MD, PhD, McMurray, John J.V., MD, PhD, Cleland, John G.F., MD, PhD, Wikstrand, John, MD, PhD, Muntendam, Pieter, MD, PhD, Wienhues-Thelen, Ursula, PhD, Latini, Roberto, MD, PhD, Askevold, Erik Tandberg, MD, PhD, Gravning, Jørgen, MD, PhD, Dahl, Christen P., MD, PhD, Broch, Kaspar, MD, PhD, Yndestad, Arne, PhD, Gullestad, Lars, MD, PhD, Ueland, Thor, PhD

“…Abstract Objectives This study sought to evaluate whether a panel of biomarkers improved prognostication in patients with heart failure (HF) and reduced…”
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sST2 Predicts Outcome in Chronic Heart Failure Beyond NT−proBNP and High-Sensitivity Troponin T by Emdin, Michele, Aimo, Alberto, Vergaro, Giuseppe, Bayes-Genis, Antoni, Lupón, Josep, Latini, Roberto, Meessen, Jennifer, Anand, Inder S., Cohn, Jay N., Gravning, Jørgen, Gullestad, Lars, Broch, Kaspar, Ueland, Thor, Nymo, Ståle H., Brunner-La Rocca, Hans-Peter, de Boer, Rudolf A., Gaggin, Hanna K., Ripoli, Andrea, Passino, Claudio, Januzzi, James L.

“…Soluble suppression of tumorigenesis-2 (sST2) is a biomarker related to inflammation and fibrosis. This study assessed the independent prognostic value of sST2…”
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Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans by Rutkovskiy, Arkady, Sagave, Julia, Czibik, Gabor, Baysa, Anton, Zihlavnikova Enayati, Katarina, Hillestad, Vigdis, Dahl, Christen Peder, Fiane, Arnt, Gullestad, Lars, Gravning, Jørgen, Ahmed, Shakil, Attramadal, Håvard, Valen, Guro, Vaage, Jarle

“…We aimed to study the cardiac expression of bone morphogenetic protein 2, its receptor 1 b, and connective tissue growth factor, factors implicated in cardiac…”
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Soluble glycoprotein 130 predicts fatal outcomes in chronic heart failure: analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) by Askevold, Erik Tandberg, Nymo, Ståle, Ueland, Thor, Gravning, Jørgen, Wergeland, Ragnhild, Kjekshus, John, Yndestad, Arne, Cleland, John G F, McMurray, John J V, Aukrust, Pål, Gullestad, Lars

“…Glycoprotein 130 (gp130) is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family, which may be involved in the progression of…”
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