Search Results - "Graves, Christina"
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Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss
Published in Cell (09-01-2020)“…Enteric-associated neurons (EANs) are closely associated with immune cells and continuously monitor and modulate homeostatic intestinal functions, including…”
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Enteric bacteria promote human and mouse norovirus infection of B cells
Published in Science (American Association for the Advancement of Science) (07-11-2014)“…The cell tropism of human noroviruses and the development of an in vitro infection model remain elusive. Although susceptibility to individual human norovirus…”
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Critical Role for a Subset of Intestinal Macrophages in Shaping Gut Microbiota in Adult Zebrafish
Published in Cell reports (Cambridge) (09-10-2018)“…The gut microbiota is strongly influenced by environmental factors, although host contribution is far less understood. We leveraged macrophage-deficient…”
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4
Evolutionary history and metabolic insights of ancient mammalian uricases
Published in Proceedings of the National Academy of Sciences - PNAS (11-03-2014)“…Uricase is an enzyme involved in purine catabolism and is found in all three domains of life. Curiously, uricase is not functional in some organisms despite…”
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Human norovirus culture in B cells
Published in Nature protocols (01-12-2015)“…Human noroviruses are a leading cause of foodborne disease. Here the authors facilitate the study of these viruses with protocols for culturing them in human B…”
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6
Aging, inflammation, immunity and periodontal disease
Published in Periodontology 2000 (01-10-2016)“…The increased prevalence and severity of periodontal disease have long been associated with aging, such that this oral condition affects the majority of the…”
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mTOR signaling is required for phagocyte free radical production, GLUT1 expression, and control of Staphylococcus aureus infection
Published in mBio (12-06-2024)“…Mammalian target of rapamycin (mTOR) is a key regulator of metabolism in the mammalian cell. Here, we show the essential role for mTOR signaling in the immune…”
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Zebrafish harbor diverse intestinal macrophage populations including a subset intimately associated with enteric neural processes
Published in iScience (25-06-2021)“…Intestinal macrophages are essential for gut health but remain understudied outside of human and mouse systems. Here, we establish zebrafish as a powerful…”
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9
Pattern-restricted one-cycle permutations with a pattern-restricted cycle form
Published in Enumerative combinatorics and applications (01-10-2024)Get full text
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10
A method for high purity intestinal epithelial cell culture from adult human and murine tissues for the investigation of innate immune function
Published in Journal of immunological methods (01-12-2014)“…Intestinal epithelial cells (IECs) serve as an important physiologic barrier between environmental antigens and the host intestinal immune system. Thus, IECs…”
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11
Chronic early life stress alters the neuroimmune profile and functioning of the developing zebrafish gut
Published in Brain, behavior, & immunity. Health (01-08-2023)“…Chronic early life stress (ELS) potently impacts the developing central nervous and immune systems and is associated with the onset of gastrointestinal disease…”
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Lipid mediators and biomarkers associated with type 1 diabetes development
Published in JCI insight (20-08-2020)“…Type 1 diabetes (T1D) is a consequence of autoimmune β cell destruction, but the role of lipids in this process is unknown. We previously reported that…”
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Downstream mediators of the intratumoral interferon response suppress antitumor immunity, induce gemcitabine resistance and associate with poor survival in human pancreatic cancer
Published in Cancer Immunology, Immunotherapy (01-12-2015)“…The cancer microenvironment allows tumor cells to evade immune surveillance through a variety of mechanisms. While interferon-γ (IFNγ) is central to effective…”
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14
Patient and Caregiver Perceptions of Animal Assisted Activity in Orthodontics
Published in Animals (Basel) (21-07-2022)“…Dental anxiety affects up to 21% of children and 80% of adults and is associated with lifelong dental avoidance. Animal assisted activity (AAA) is widely used…”
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Intestinal Epithelial Cell Regulation of Adaptive Immune Dysfunction in Human Type 1 Diabetes
Published in Frontiers in immunology (10-01-2017)“…Environmental factors contribute to the initiation, progression, and maintenance of type 1 diabetes (T1D), although a single environmental trigger for disease…”
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16
More reliable graphs are not always stronger
Published in Networks (01-06-2023)“…A graph G$$ G $$ is stronger than a graph H$$ H $$ if G$$ G $$ has at least as many connected spanning subgraphs of size k$$ k $$ as H$$ H $$ for any positive…”
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Pattern-restricted permutations composed of 3-cycles
Published in Discrete mathematics (01-07-2022)“…In this paper, we characterize and enumerate pattern-avoiding permutations composed of only 3-cycles. In particular, we answer the question for the six…”
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18
A new statistic on Dyck paths for counting 3-dimensional Catalan words
Published in Discrete mathematics (01-03-2023)“…A 3-dimensional Catalan word is a word on three letters so that the subword on any two letters is a Dyck path. For a given Dyck path D, a recently defined…”
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Adenine Synthesis in a Model Prebiotic Reaction: Connecting Origin of Life Chemistry with Biology
Published in Journal of chemical education (01-12-2011)“…Many high school laboratory experiments demonstrate concepts related to biological evolution, but few exist that allow students to investigate life’s chemical…”
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Reliability polynomials having arbitrarily many inflection points
Published in Networks (01-08-2014)“…In this article, we show that for every n, there exists a multigraph whose reliability polynomial has at least n inflection points. © 2014 Wiley Periodicals,…”
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