Search Results - "Graves, A"
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A Novel Connectionist System for Unconstrained Handwriting Recognition
Published in IEEE transactions on pattern analysis and machine intelligence (01-05-2009)“…Recognizing lines of unconstrained handwritten text is a challenging task. The difficulty of segmenting cursive or overlapping characters, combined with the…”
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2
Microchromosomes are building blocks of bird, reptile, and mammal chromosomes
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-2021)“…Microchromosomes, once considered unimportant shreds of the chicken genome, are gene-rich elements with a high GC content and few transposable elements. Their…”
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3
Evolution of vertebrate sex chromosomes and dosage compensation
Published in Nature reviews. Genetics (01-01-2016)“…Key Points Vertebrate chromosomes and genomes are very conserved, but different genome regions have evolved to trigger the determination of sex in different…”
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4
Sex reversal triggers the rapid transition from genetic to temperature-dependent sex
Published in Nature (London) (02-07-2015)“…The first report of reptile sex reversal in the wild and rapid transition between genetic and environmental sex determination in the Australian bearded dragon…”
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Polygenic sex determination in vertebrates – is there any such thing?
Published in Trends in genetics (01-04-2023)“…Polygenic sex determination (PSD) is defined as the determination of sexual phenotype by the combined action of two or more genes at independently inherited…”
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Circuit‐theory applications to connectivity science and conservation
Published in Conservation biology (01-04-2019)“…Conservation practitioners have long recognized ecological connectivity as a global priority for preserving biodiversity and ecosystem function. In the early…”
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Feasibility and safety of early combined cognitive and physical therapy for critically ill medical and surgical patients: the Activity and Cognitive Therapy in ICU (ACT-ICU) trial
Published in Intensive care medicine (01-03-2014)“…Purpose Cognitive impairment after critical illness is common and debilitating. We developed a cognitive therapy program for critically ill patients and…”
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The total costs of soil degradation in England and Wales
Published in Ecological economics (01-11-2015)“…There is growing concern that the way that soils are used often results in their degradation, giving rise to significant costs, both to direct users of soils…”
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Global exports draining local water resources: Land concentration, food exports and water grabbing in the Ica Valley (Peru)
Published in World development (01-05-2024)“…•The Ica valley (Peru) experienced an increasing level LSLA replacing traditional local agriculture based on small-farming.•We analyze the effect of land…”
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The structure, function and evolution of a complete human chromosome 8
Published in Nature (London) (06-05-2021)“…The complete assembly of each human chromosome is essential for understanding human biology and evolution 1 , 2 . Here we use complementary long-read…”
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Weird animal genomes and the evolution of vertebrate sex and sex chromosomes
Published in Annual review of genetics (01-01-2008)“…Humans, mice, and even kangaroos have an XX female:XY male system of sex determination, in which the Y harbors a male-dominant sex-determining gene SRY. Birds…”
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Characterizing the Major Structural Variant Alleles of the Human Genome
Published in Cell (24-01-2019)“…In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read sequence data and analyzed SVs for fifteen human…”
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Discovery and genotyping of structural variation from long-read haploid genome sequence data
Published in Genome research (01-05-2017)“…In an effort to more fully understand the full spectrum of human genetic variation, we generated deep single-molecule, real-time (SMRT) sequencing data from…”
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Prostate-Specific Membrane Antigen (PSMA) Theranostics for Treatment of Oligometastatic Prostate Cancer
Published in International journal of molecular sciences (09-11-2021)“…Theranostics, a combination of therapy and diagnostics, is a field of personalized medicine involving the use of the same or similar radiopharmaceutical agents…”
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Sex Chromosome Specialization and Degeneration in Mammals
Published in Cell (10-03-2006)“…Sex chromosomes—particularly the human Y—have been a source of fascination for decades because of their unique transmission patterns and their peculiar…”
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Evolution of Human-Specific Neural SRGAP2 Genes by Incomplete Segmental Duplication
Published in Cell (11-05-2012)“…Gene duplication is an important source of phenotypic change and adaptive evolution. We leverage a haploid hydatidiform mole to identify highly identical…”
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Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination
Published in PLoS genetics (15-04-2021)“…How temperature determines sex remains unknown. A recent hypothesis proposes that conserved cellular mechanisms (calcium and redox; 'CaRe' status) sense…”
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Employment Outcomes After Critical Illness: An Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychological Dysfunction in ICU Survivors Cohort
Published in Critical care medicine (01-11-2016)“…OBJECTIVES:To characterize survivors’ employment status after critical illness and to determine if duration of delirium during hospitalization and residual…”
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Current approaches using genetic distances produce poor estimates of landscape resistance to interindividual dispersal
Published in Molecular ecology (01-08-2013)“…Landscape resistance reflects how difficult it is for genes to move across an area with particular attributes (e.g. land cover, slope). An increasingly popular…”
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Quantifying effectiveness and best practices for bumblebee identification from photographs
Published in Scientific reports (10-01-2024)“…Understanding pollinator networks requires species level data on pollinators. New photographic approaches to identification provide avenues to data collection…”
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