Search Results - "Gravatt, G. L."

Pyrazole analogues of the bispyrrolecarboxamide anti-tumour antibiotics: synthesis, DNA binding and anti-tumour properties by Lee, H H, Boyd, M, Gravatt, G L, Denny, W A

“…Four bispyrazole compounds have been prepared as potentially more stable analogues of the DNA minor groove binding polypyrrole compounds netropsin and…”
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Asymmetric Synthesis via Chiral Transition Metal Auxiliaries [and Discussion] by Davies, S. G., Bashiardes, G., Beckett, R. P., Coote, S. J., Dordor-Hedgecock, Isabelle M., Goodfellow, C. L., Gravatt, G. L., McNally, J. P., Whittaker, M., Reetz, M. T.

“…Stoichiometric reagents for the control of the absolute stereochemistry of new chiral centres produced during reactions involving carbon--carbon bond formation…”
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DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard by Gourdie, Trudi A, Valu, Kisione K, Gravatt, G. Lance, Boritzki, Theodore J, Baguley, Bruce C, Wakelin, Laurence P. G, Wilson, William R, Woodgate, Paul D, Denny, William A

“…A series of DNA-targeted aniline mustards have been prepared, and their chemical reactivity and in vitro and in vivo cytotoxicity have been evaluated and…”
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DNA-directed alkylating agents. 3. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the length of the linker chain by Valu, Kisione K, Gourdie, Trudi A, Boritzki, Theodore J, Gravatt, G. Lance, Baguley, Bruce C, Wilson, William R, Wakelin, Laurence P. G, Woodgate, Paul D, Denny, William A

“…Four series of acridine-linked aniline mustards have been prepared and evaluated for in vitro cytotoxicity, in vivo antitumor activity, and DNA cross-linking…”
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DNA-directed alkylating agents. 4. 4-Anilinoquinoline-based minor groove directed aniline mustards by Gravatt, G. Lance, Baguley, Bruce C, Wilson, William R, Denny, William A

“…A series of 4-anilinoquinoline-linked aniline mustards of widely varying mustard reactivity were prepared and evaluated for their antitumor activity. The…”
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DNA-Directed Alkylating Agents. 6. Synthesis and Antitumor Activity of DNA Minor Groove-Targeted Aniline Mustard Analogs of Pibenzimol (Hoechst 33258) by Gravatt, G. Lance, Baguley, Bruce C, Wilson, William R, Denny, William A

“…A series of nitrogen mustard analogues of the DNA minor groove binding fluorophore pibenzimol (Hoechst 33258) have been synthesized and evaluated for antitumor…”
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Oxidation of vicinal diols to .alpha.-dicarbonyl compounds by trifluoroacetic anhydride-activated dimethyl sulfoxide by Amon, Catherine M, Banwell, Martin G, Gravatt, G. Lance

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DNA-directed alkylating agents. VI: Synthesis and antitumor activity of DNA minor groove-targeted aniline Mustard analogues of pibenzimol (Hoechst 33258) by GRAVATT, G. L, BAGULEY, B. C, WILSON, W. R, DENNY, W. A

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DNA-directed alkylating agents. IV, 4-anilinoquinoline-based minor groove directed aniline mustards by GRAVATT, G. L, BAGULEY, B. C, WILSON, W. R, DENNY, W. A

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DNA-directed alkylating agents. III, Structure-activity relationships for acridine-linked aniline mustards. Consequences of varying the lenght of the linker chain by VALU, K. K, GOURDIE, T. A, BORITZKI, T. J, GRAVATT, G. L, BAGHULEY, B. C, WILSON, W. R, WAKELIN, L. P. G, WOODGATE, P. D, DENNY, W. A

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DNA-directed alkylating agents. I: Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard by GOURDIE, T. A, VALU, K. K, GRAVATT, G. L, BORITZKI, T. J, BAGULEY, B. C, WAKELIN, L. P. G, WILSON, W. R, WOODGATE, P. D, DENNY, W. A

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The influence of organometallic chemistry on organic synthesis: present and future - Asymmetric synthesis via chiral transition metal auxiliaries by Davies, Stephen Graham, Bashiardes, G., Beckett, R. P., Coote, S. J., Dordor-Hedgecock, Isabelle M., Goodfellow, C. L., Gravatt, G. L., McNally, J. P., Whittaker, M.

“…Stoichiometric reagents for the control of the absolute stereochemistry of new chiral centres produced during reactions involving carbon-carbon bond formation…”
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