Search Results - "Graux, C"

Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast by GRAUX, C, COOLS, J, MICHAUX, L, VANDENBERGHE, P, HAGEMEIJER, A

“…For long, T-cell acute lymphoblastic leukemia (T-ALL) remained in the shadow of precursor B-ALL because it was more seldom, and showed a normal karyotype in…”
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A phase 1b/2b multicenter study of oral panobinostat plus azacitidine in adults with MDS, CMML or AML with ⩽30% blasts by Garcia-Manero, G, Sekeres, M A, Egyed, M, Breccia, M, Graux, C, Cavenagh, J D, Salman, H, Illes, A, Fenaux, P, DeAngelo, D J, Stauder, R, Yee, K, Zhu, N, Lee, J-H, Valcarcel, D, MacWhannell, A, Borbenyi, Z, Gazi, L, Acharyya, S, Ide, S, Marker, M, Ottmann, O G

“…Treatment with azacitidine (AZA), a demethylating agent, prolonged overall survival (OS) vs conventional care in patients with higher-risk myelodysplastic…”
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Comparative therapeutic value of post-remission approaches in patients with acute myeloid leukemia aged 40–60 years by Cornelissen, J J, Versluis, J, Passweg, J R, van Putten, W L J, Manz, M G, Maertens, J, Beverloo, H B, Valk, P J M, van Marwijk Kooy, M, Wijermans, P W, Schaafsma, M R, Biemond, B J, Vekemans, M-C, Breems, D A, Verdonck, L F, Fey, M F, Jongen-Lavrencic, M, Janssen, J J W M, Huls, G, Kuball, J, Pabst, T, Graux, C, Schouten, H C, Gratwohl, A, Vellenga, E, Ossenkoppele, G, Löwenberg, B

“…The preferred type of post-remission therapy (PRT) in patients with acute myeloid leukemia (AML) in first complete remission (CR1) is a subject of continued…”
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Addition of the nuclear export inhibitor selinexor to standard intensive treatment for elderly patients with acute myeloid leukemia and high risk myelodysplastic syndrome by Janssen, J. J. W. M., Löwenberg, B., Manz, M., Biemond, B. J., Westerweel, P. E., Klein, S. K., Fehr, M., Sinnige, H. A. M., Efthymiou, A., Legdeur, M. C. J. C., Pabst, T., Gregor, M., van der Poel, M. W. M., Deeren, D., Tick, L. W., Jongen-Lavrencic, M., van Obbergh, F., Boersma, R. S., de Weerdt, O., Chalandon, Y., Heim, D., Spertini, O., van Sluis, G., Graux, C., Stüssi, G., van Norden, Y., Ossenkoppele, G. J.

“…Treatment results of AML in elderly patients are unsatisfactory. In an open label randomized phase II study, we investigated whether addition of the XPO1…”
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Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia by Marynen, Peter, Hagemeijer, Anne, Graux, C, Cools, J, Melotte, C, Quentmeier, H, Ferrando, A, Levine, R, Vermeesch, J.R, Stul, M, Dutta, B, Boeckx, N, Bosly, A, Heimann, P, Uyttebroeck, A, Mentens, N, Somers, R, MacLeod, R.A.F, Drexler, H.G, Look, A.T, Gilliland, D.G, Michaux, L, Vandenberghe, P, Wlodarska, I

“…In T-cell acute lymphoblastic leukemia (T-ALL), transcription factors are known to be deregulated by chromosomal translocations, but mutations in protein…”
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171: Cycling hypoxia amplifies tumor microenvironment inflammation by Michiels, C, Tellier, C, Graux, C, Finet, L, Raes, M, Feron, O

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Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia by Graux, C, Stevens-Kroef, M, Lafage, M, Dastugue, N, Harrison, C J, Mugneret, F, Bahloula, K, Struski, S, Grégoire, M J, Nadal, N, Lippert, E, Taviaux, S, Simons, A, Kuiper, R P, Moorman, A V, Barber, K, Bosly, A, Michaux, L, Vandenberghe, P, Lahortiga, I, De Keersmaecker, K, Wlodarska, I, Cools, J, Hagemeijer, A, Poirel, H A

“…Episomes with the NUP214-ABL1 fusion gene have been observed in 6% of T-ALL. In this multicentric study we collected 27 cases of NUP214-ABL1 -positive T-ALL…”
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Unhealthy effects of atmospheric temperature and pressure on the occurrence of myocardial infarction and coronary deaths. A 10-year survey: the Lille-World Health Organization MONICA project (Monitoring trends and determinants in cardiovascular disease) by Danet, S, Richard, F, Montaye, M, Beauchant, S, Lemaire, B, Graux, C, Cottel, D, Marécaux, N, Amouyel, P

“…Associations between an increase in coronary heart disease occurrence and low atmospheric temperatures have been reported from mortality data and hospital…”
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A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias by SPELEMAN, F, CAUWELIER, B, BOOGAERTS, M, DE MOERLOOSE, B, BENOIT, Y, SELLESLAG, D, BILLIET, J, ROBERT, A, HUGUET, F, VANDENBERGHE, P, DE PAEPE, A, MARYNEN, P, DASTUGUE, N, HAGEMEIJER, A, COOLS, J, VERHASSELT, B, POPPE, B, VAN ROY, N, VANDESOMPELE, J, GRAUX, C, UYTTEBROECK, A

“…Chromosomal translocations with breakpoints in T-cell receptor (TCR) genes are recurrent in T-cell malignancies. These translocations involve the TCRalphadelta…”
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Translocation t(14;18) is not associated with inferior outcome in chronic lymphocytic leukemia by Put, N, Meeus, P, Chatelain, B, Rack, K, Boeckx, N, Nollet, F, Graux, C, Van Den Neste, E, Janssens, A, Madoe, V, Van Hoof, A, Bilhou-Nabera, C, Wlodarska, I, Vandenberghe, P, Michaux, L

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Safety and efficacy of azacitidine in Belgian patients with high-risk myelodysplastic syndromes, acute myeloid leukaemia, or chronic myelomonocytic leukaemia: results of a real-life, non-interventional post-marketing survey by Beguin, Y., Selleslag, D., Meers, S., Graux, C., Bries, G., Deeren, D., Vrelust, I., Ravoet, C., Theunissen, K., Voelter, V., Potier, H., Trullemans, F., Noens, L., Mineur, P.

“…Objectives: We evaluated azacitidine (Vidaza ® ) safety and efficacy in patients with myelodysplastic syndrome (MDS), acute myeloid leukaemia (AML), and…”
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Management of myelodysplastic syndromes in adults: guidelines from the Belgian Haematological Society by Meers, S, Breems, D, Bries, G, Delforge, M, Graux, C, Ravoet, C, Selleslag, D, Noens, L

“…Myelodysplastic syndromes (MDS) represent a heterogeneous group of haematological disorders characterized by ineffective haematopoiesis and an increased risk…”
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Unusual cause of severe anaemia in a patient with metastatic haemangiopericytoma by Vanhaudenarde, V, Duck, L, Mazzeo, F, Graux, C, Jamar, F, Coche, E, Galant, C, Machiels, J P

“…Haemangiopericytoma is a rare tumor of vascular origin. We report the case of patient with severe refractory anaemia due to peripheral destruction of red blood…”
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Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRβ-HOXA rearrangement : a study of the Groupe Francophone de Cytogénétique Hématologique by CAUWELIER, B, CAVE, H, GRAGOIRE, M.-J, JONVEAUX, P, LAFAGE-POCHITALOFF, M, MOZZICCONACCI, M. J, TERRE, C, LUQUET, I, CORNILLET-LEFEBVRE, P, LAURENCE, B, PLESSIS, G, LEFEBVRE, C, GERVAIS, C, LEROUX, D, ANTOINE, H, GRAUX, C, MAUVIEUX, L, HEIMANN, P, CHALAS, C, CLAPPIER, E, VERHASSELT, B, BENOIT, Y, MOERLOOSE, B. D, LESSARD, M, POPPE, B, VAN ROY, N, KEERSMAECKER, K. D, COOLS, J, SIGAUX, F, SOULIER, J, HAGEMEIJER, A, PAEPE, A. D, DASTUGUE, N, BERGER, R, BARIN, C, SPELEMAN, F, PEROT, C, VAN DEN AKKER, J, MUGNERET, F, CHARRIN, C, PAGES, M. P

“…Recently, we and others described a new chromosomal rearrangement, that is, inv(7)(p15q34) and t(7; 7)(p15; q34) involving the T-cell receptor beta (TCR beta )…”
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Transition from EML1-ABL1 to NUP214-ABL1 positivity in a patient with acute T-lymphoblastic leukemia by DE KEERSMAECKER, K, LAHORTIGA, I, GRAUX, C, MARYNEN, P, MAERTENS, J, COOLS, J, VANDENBERGHE, P

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PHASE 2 STUDY OF PEVONEDISTAT + AZACITIDINE VERSUS AZACITIDINE IN PATIENTS WITH HIGHER-RISK MYELODYSPLASTIC SYNDROMES/CHRONIC MYELOMONOCYTIC LEUKEMIA OR LOW-BLAST ACUTE MYELOGENOUS LEUKEMIA (NCT02610777) by L. Adès, J. Watts, A. Radinoff, M.A. Sangerman, M. Cerrano, P.F. Lopez, J. Zeidner, M.D. Campelo, C. Graux, J. Liesveld, D. Selleslag, N. Tzvetkov, R.J. Fram, D. Zhao, J. Bell, S. Friedlander, D.V. Faller, M.A. Sekeres

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Molecular Minimal Residual Disease in Acute Myeloid Leukemia by Jongen-Lavrencic, Mojca, Grob, Tim, Hanekamp, Diana, Kavelaars, François G, al Hinai, Adil, Zeilemaker, Annelieke, Erpelinck-Verschueren, Claudia A.J, Gradowska, Patrycja L, Meijer, Rosa, Cloos, Jacqueline, Biemond, Bart J, Graux, Carlos, van Marwijk Kooy, Marinus, Manz, Markus G, Pabst, Thomas, Passweg, Jakob R, Havelange, Violaine, Ossenkoppele, Gert J, Sanders, Mathijs A, Schuurhuis, Gerrit J, Löwenberg, Bob, Valk, Peter J.M

“…Among patients with acute myeloid leukemia, gene sequencing during remission revealed that persistent mutations in genes associated with clonal hematopoiesis…”
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High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia

“…High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia Original Article, N Engl J Med 2009:361;1235-1248.. In the Methods section of the Abstract…”
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Bronchobiliary fistula and cholangiocarcinoma: a case report and principles of management by Delande, S, Goffette, P, Verbaandert, C, Rahier, J, Graux, C, Mazzeo, F, Humblet, Y, Machiels, J P

“…A 64-year-old woman was admitted with fever and cough. At admission, she had jaundice, hepatomegaly, and green-stained sputum. Computed tomography (CT) showed…”
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Multipotent mesenchymal stromal cells as treatment for poor graft function after allogeneic hematopoietic cell transplantation: A multicenter prospective analysis by Servais, Sophie, Baron, Frédéric, Lechanteur, Chantal, Seidel, Laurence, Baudoux, Etienne, Briquet, Alexandra, Selleslag, Dominik, Maertens, Johan, Poire, Xavier, Schroyens, Wilfried, Graux, Carlos, De Becker, Ann, Zachee, Pierre, Ory, Aurélie, Herman, Julie, Kerre, Tessa, Beguin, Yves

“…Poor graft function (PGF) is a rare but serious complication of allogeneic hematopoietic cell transplantation (alloHCT). Due to their hematopoietic supporting…”
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