Search Results - "Grauer, Matthias"
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Hematopoietic Development from Human Induced Pluripotent Stem Cells
Published in Annals of the New York Academy of Sciences (01-09-2009)“…A decade of research on human embryonic stem cells (ESC) has paved the way for the discovery of alternative approaches to generating pluripotent stem cells…”
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Interactions between Cdx genes and retinoic acid modulate early cardiogenesis
Published in Developmental biology (01-06-2011)“…Cdx transcription factors regulate embryonic positional identities and have crucial roles in anteroposterior patterning (AP) processes of all three germ…”
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CDX2 regulates Human Leukemic Cell Clonogenicity and in Vivo Repopulation Capacity
Published in Blood (06-12-2014)“…Objectives: The caudal-type homeobox (CDX) gene family has been mainly studied during early development for its role in axial elongation and antero-posterior…”
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Innate immune system favors emergency monopoiesis at the expense of DC‐differentiation to control systemic bacterial infection in mice
Published in European journal of immunology (01-10-2015)“…DCs are professional APCs playing a crucial role in the initiation of T‐cell responses to combat infection. However, systemic bacterial infection with various…”
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A Dual Role of Evi-1 During Developmental Hematopoiesis
Published in Blood (16-11-2012)“…Abstract 765 The Evi-1 locus was originally identified as a common site of retroviral integration in murine myeloid tumors. Several reports associate Evi-1…”
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The Innate Immune System Favors Emergency Monopoiesis at the Expense of DC Differentiation to Control Bacterial Infections
Published in Blood (06-12-2014)“…Dendritic cells (DCs) are critical in host defense against infection, bridging the innate and adaptive immune system. Patients with sepsis display reduced…”
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Evi-1 Regulates Myelopoiesis and Hematopoietic Stem Cell Development in Zebrafish and Human Pluripotent Stem Cells
Published in Blood (18-11-2011)“…Abstract 1281 The Evi-1 locus was originally identified as a common site of retroviral integration in murine myeloid tumors. Over the last years, Evi-1 evolved…”
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Aldehyde dehydrogenase activity in serous ovarian carcinoma
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e15577 Background: Only specific subpopulations of tumor cells, so called cancer stem cells (CSC) may initiate and maintain tumors. The phenotype…”
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EVI-1 Mediates Apoptosis Resistance Via CD261 Induction and Enhances Leukemogenic Potential in Human Acute Lymphoblastic Leukemia
Published in Blood (18-11-2011)“…Abstract 1356 The transcriptional regulator ecotropic viral integration site-1 (EVI-1) has mainly been studied for its role in myeloid malignancies, in which…”
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10
Hematopoietic Development From Human Induced Pluripotent Stem Cells
Published in Blood (20-11-2009)“…Abstract 2530 Poster Board II-507 A decade of research on human embryonic stem cells (ESC) has paved the way for the discovery of alternative approaches to…”
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