Search Results - "Grassi, Sara"

Lipid rafts and neurodegeneration: structural and functional roles in physiologic aging and neurodegenerative diseases by Grassi, Sara, Giussani, Paola, Mauri, Laura, Prioni, Simona, Sonnino, Sandro, Prinetti, Alessandro

“…Lipid rafts are small, dynamic membrane areas characterized by the clustering of selected membrane lipids as the result of the spontaneous separation of…”
Get full text

Sphingosine 1-Phosphate Receptors and Metabolic Enzymes as Druggable Targets for Brain Diseases by Grassi, Sara, Mauri, Laura, Prioni, Simona, Cabitta, Livia, Sonnino, Sandro, Prinetti, Alessandro, Giussani, Paola

“…The central nervous system is characterized by a high content of sphingolipids and by a high diversity in terms of different structures. Stage- and…”
Get full text

Isolation and Analysis of Detergent-Resistant Membrane Fractions by Aureli, Massimo, Grassi, Sara, Sonnino, Sandro, Prinetti, Alessandro

“…The hypothesis that the Golgi apparatus is capable of sorting proteins and sending them to the plasma membrane through "lipid rafts," membrane lipid domains…”
Get more information

Paradoxical Psoriasis Induced by Anti-TNFα Treatment: Evaluation of Disease-Specific Clinical and Genetic Markers by Bucalo, Agostino, Rega, Federica, Zangrilli, Arianna, Silvestri, Valentina, Valentini, Virginia, Scafetta, Giorgia, Marraffa, Federica, Grassi, Sara, Rogante, Elena, Piccolo, Arianna, Cucchiara, Salvatore, Viola, Franca, Bianchi, Luca, Ottini, Laura, Richetta, Antonio

“…Paradoxical psoriasis (PP) may occur during treatment with anti-tumor necrosis factor-alpha (TNF-α) drugs in various chronic immune-mediated diseases, mainly…”
Get full text

The Role of 3-O-Sulfogalactosylceramide, Sulfatide, in the Lateral Organization of Myelin Membrane by Grassi, Sara, Prioni, Simona, Cabitta, Livia, Aureli, Massimo, Sonnino, Sandro, Prinetti, Alessandro

“…Sulfatide (3- O -sulfogalactosylceramide, SM4s) was isolated by Thudichum from the human brain in 1884. Together with galactosylceramide, its direct metabolic…”
Get full text

Atopic dermatitis-derived Staphylococcus aureus strains: what makes them special in the interplay with the host by Conte, Antonietta Lucia, Brunetti, Francesca, Marazzato, Massimiliano, Longhi, Catia, Maurizi, Linda, Raponi, Giammarco, Palamara, Anna Teresa, Grassi, Sara, Conte, Maria Pia

“…Atopic dermatitis (AD) is a chronic inflammatory skin condition whose pathogenesis involves genetic predisposition, epidermal barrier dysfunction, alterations…”
Get full text

Gut microbiome profile in psoriatic patients treated and untreated with biologic therapy by Valentini, Virginia, Silvestri, Valentina, Marraffa, Federica, Greco, Giulia, Bucalo, Agostino, Grassi, Sara, Gagliardi, Antonella, Mazzotta, Annamaria, Ottini, Laura, Richetta, Antonio Giovanni

“…There are increasing data about the role of the gut microbiome in various autoimmune diseases, including psoriasis, a chronic inflammatory and immune‐mediated…”
Get full text

Increased intestinal barrier permeability in patients with moderate to severe plaque‐type psoriasis by Richetta, Antonio Giovanni, Grassi, Sara, Moliterni, Elisa, Chello, Camilla, Calvieri, Camilla, Carnevale, Roberto, Peruzzi, Mariangela, Violi, Francesco, Calvieri, Stefano

Get full text

Unusual patterns of presentation of frontal fibrosing alopecia: A clinical and trichoscopic analysis of 98 patients by Rossi, Alfredo, MD, PhD, Grassi, Sara, MD, Fortuna, Maria Caterina, MD, Garelli, Valentina, MD, Pranteda, Giulia, MD, Caro, Gemma, MD, Carlesimo, Marta, MD

Get full text

Case Report: Cetuximab and nivolumab use in advanced cutaneous squamous cell carcinoma resistant to chemotherapy [version 2; peer review: 2 approved] by Sernicola, Alvise, Lampitelli, Salvatore, Marraffa, Federica, Maddalena, Patrizia, Grassi, Sara, Richetta, Antonio Giovanni, Calvieri, Stefano

“…We present the case of a 60-year-old man with unresectable cutaneous squamous cell carcinoma (cSCC) of the sternal area, which was not amenable to radiation…”
Get full text

Consensus based optimization with memory effects: Random selection and applications by Borghi, Giacomo, Grassi, Sara, Pareschi, Lorenzo

“…In this work we extend the class of Consensus-Based Optimization (CBO) metaheuristic methods by considering memory effects and a random selection strategy. The…”
Get full text

Journal of Molecular Neuroscience (JOMN)—Special Issue European Society for Neurochemistry (ESN) First Virtual Conference, May 2021 by Blumrich, Eva-Maria, Grassi, Sara

Get full text

Lipid membrane domains in the brain by Aureli, Massimo, Grassi, Sara, Prioni, Simona, Sonnino, Sandro, Prinetti, Alessandro

“…The brain is characterized by the presence of cell types with very different functional specialization, but with the common trait of a very high complexity of…”
Get full text

Sphingolipids and neuronal degeneration in lysosomal storage disorders by Grassi, Sara, Chiricozzi, Elena, Mauri, Laura, Sonnino, Sandro, Prinetti, Alessandro

“…Ceramide, sphingomyelin, and glycosphingolipids (both neutral and acidic) are characterized by the presence in the lipid moiety of an aliphatic base known as…”
Get full text

Lipid rafts as platforms for sphingosine 1-phosphate metabolism and signalling by D'Aprile, Chiara, Prioni, Simona, Mauri, Laura, Prinetti, Alessandro, Grassi, Sara

“…Spontaneous segregation of cholesterol and sphingolipids as a liquid-ordered phase leads to their clustering in selected membrane areas, the lipid rafts. These…”
Get full text

Isolation and Analysis of Lipid Rafts from Neural Cells and Tissues by Grassi, Sara, Giussani, Paola, Mauri, Laura, Prioni, Simona, Prinetti, Alessandro

“…Lipid rafts are membrane areas characterized by the clustering of selected membrane lipids, as the result of their phase separation forming a liquid-ordered…”
Get more information

Lipid Rafts in Neurodegeneration and Neuroprotection by Sonnino, Sandro, Aureli, Massimo, Grassi, Sara, Mauri, Laura, Prioni, Simona, Prinetti, Alessandro

“…The collective properties of the lipids that form biological membranes give rise to a very high level of lateral organization within the membranes…”
Get full text

Identification of the Lipid Antigens Recognized by rHIgM22, a Remyelination-Promoting Antibody by Grassi, Sara, Cabitta, Livia, Prioni, Simona, Mauri, Laura, Ciampa, Maria Grazia, Yokoyama, Noriko, Iwabuchi, Kazuhisa, Zorina, Yana, Prinetti, Alessandro

“…Failure of the immune system to discriminate myelin components from foreign antigens plays a critical role in the pathophysiology of multiple sclerosis. In…”
Get full text

Ustekinumab for the treatment of moderate‐to‐severe plaque psoriasis in a solid organ transplanted recipient: A case report by Richetta, Antonio, Marraffa, Federica, Grassi, Sara, Aquila, Emilia, Dybala, Agnieszka, Aprile, Francesca, Merli, Manuela

Get full text

Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson’s disease by Zucca, Fabio A., Vanna, Renzo, Cupaioli, Francesca A., Bellei, Chiara, De Palma, Antonella, Di Silvestre, Dario, Mauri, Pierluigi, Grassi, Sara, Prinetti, Alessandro, Casella, Luigi, Sulzer, David, Zecca, Luigi

“…During aging, neuronal organelles filled with neuromelanin (a dark-brown pigment) and lipid bodies accumulate in the brain, particularly in the substantia…”
Get full text