Search Results - "Graser, Andreas"

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  1. 1

    Rigorous approach to scheduling of sterile drug product manufacturing by Eberle, Lukas, Capón-García, Elisabet, Sugiyama, Hirokazu, Graser, Andreas, Schmidt, Rainer, Hungerbühler, Konrad

    Published in Computers & chemical engineering (02-11-2016)
    “…•Immediate-precedence model of sterile drug product manufacturing.•Pharma-specific constraints incorporated, e.g., sterile holding time, and…”
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    Journal Article
  2. 2

    Optimal Scheduling of Liquid Drug Product Manufacturing by Eberle, Lukas G., Capón-Garcia, Elisabet, Senninger, Martin, Sugiyama, Hirokazu, Graser, Andreas, Schmidt, Rainer, Hungerbühler, Konrad

    “…Production scheduling in pharmaceutical production must consider a complex set of features, including due dates, shelf-life, reduced possibility for task…”
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    Book Chapter
  3. 3

    Data-Based Tiered Approach for Improving Pharmaceutical Batch Production Processes by Eberle, Lukas G., Sugiyama, Hirokazu, Papadokonstantakis, Stavros, Graser, Andreas, Schmidt, Rainer, Hungerbühler, Konrad

    “…Enhancing yield in production is paramount for success in the increasingly competitive pharmaceutical industry, especially for manufacturers of costly…”
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    Book Chapter
  4. 4

    Data-driven tiered procedure for enhancing yield in drug product manufacturing by Eberle, Lukas, Sugiyama, Hirokazu, Papadokonstantakis, Stavros, Graser, Andreas, Schmidt, Rainer, Hungerbühler, Konrad

    Published in Computers & chemical engineering (06-04-2016)
    “…•Generic, data-driven yield enhancement procedure for drug product manufacturing.•A four-step procedure, combining heuristics and statistics, is…”
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    Journal Article
  5. 5

    Innovative approach for identifying root causes of glass defects in sterile drug product manufacturing by Eberle, Lukas, Svensson, Alexander, Graser, Andreas, Luemkemann, Joerg, Sugiyama, Hirokazu, Schmidt, Rainer, Hungerbuehler, Konrad

    “…In sterile drug product manufacturing, scratched and broken glass containers (i.e., vials) cause product losses, glass particles, equipment contamination and…”
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    Journal Article
  6. 6

    Improving Pharmaceutical Batch Production Processes with Data-Based Tiered Approach by Eberle, Lukas G., Sugiyama, Hirokazu, Papadokonstantakis, Stavros, Graser, Andreas, Schmidt, Rainer, Hungerbühler, Konrad

    “…Improving the yield of batch-wise production is an increasingly important topic for the pharmaceutical industry; reasons for that include the rising public…”
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    Book Chapter
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    Cytotoxic T lymphocytes responding to low dose TRP2 antigen are induced against B16 melanoma by liposome- encapsulated TRP2 peptide and CpG DNA adjuvant by JEROME, Valérie, GRASER, Andreas, MÜLLER, Rolf, KONTERMANN, Roland E, KONUR, Abdo

    Published in Journal of immunotherapy (1997) (01-05-2006)
    “…The induction of a potent and specific T cell response is a major challenge in the development of efficacious cancer vaccine strategies. We applied a novel…”
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    Journal Article
  8. 8

    Encapsulation of gadobutrol in AVE-based liposomal carriers for MR detectability by Heverhagen, Johannes T., Graser, Andreas, Fahr, Alfred, Müller, Rolf, Alfke, Heiko

    Published in Magnetic resonance imaging (01-05-2004)
    “…Artificial virus-like envelopes (AVEs) are liposomal carriers that may be useful for target-site-specific delivery of contrast agents. We speculated that T 1…”
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    Journal Article
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    Isolation from phage display libraries of lysine‐deficient human epidermal growth factor variants for directional conjugation as targeting ligands by Bach, Miriam, Hölig, Peter, Schlosser, Eva, Völkel, Tina, Graser, Andreas, Müller, Rolf, Kontermann, Roland E.

    Published in Protein engineering (01-12-2003)
    “…Ligand‐targeted anticancer therapeutics represent an opportunity for the selective and efficient delivery of drugs to tumours. The chemical coupling of ligands…”
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    Journal Article
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