Search Results - "Grasberger, H"

Citrobacter rodentium Induces Tissue-Resident Memory CD4 + T Cells by Bishu, S, Hou, G, El Zaatari, M, Bishu, S R, Popke, D, Zhang, M, Grasberger, H, Zou, W, Stidham, R W, Higgins, P D R, Spence, J R, Kamada, N, Kao, J Y

“…Tissue-resident memory T cells (T cells) are a novel population of tissue-restricted antigen-specific T cells. T cells are induced by pathogens and promote…”
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The tumour necrosis factor-alpha induced vascular permeability is associated with a reduction of VE-cadherin expression by Hofmann, S, Grasberger, H, Jung, P, Bidlingmaier, M, Vlotides, J, Janssen, O E, Landgraf, R

“…Vascular permeability is controlled by endothelial cell-to-cell junctions. Vascular endothelial (VE)-cadherin, the major component of adherence junctions (AJ)…”
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Ceftriaxone-Associated Nephrolithiasis by Grasberger, Helmut, Otto, Bärbel, Loeschke, Klaus

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Effects of growth hormone replacement therapy on levels of cortisol and cortisol-binding globulin in hypopituitary adults by Tschop, M, Lahner, H, Feldmeier, H, Grasberger, H, Morrison, KM, Janssen, OE, Attanasio, AF, Strasburger, CJ

“…OBJECTIVE: To determine if human growth hormone (hGH) replacement therapy alters pharmacokinetics of hydrocortisone (CS) substitution in hypopituitary adults…”
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Thyroid Transcription Factor 1 Rescues PAX8/p300 Synergism Impaired by a Natural PAX8 Paired Domain Mutation with Dominant Negative Activity by Grasberger, Helmut, Ringkananont, Usanee, LeFrancois, Paule, Abramowicz, Marc, Vassart, Gilbert, Refetoff, Samuel

“…Mutations in the paired domain transcription factor PAX8 are a rare cause of congenital hypothyroidism due to thyroid dysgenesis. We identified a novel and…”
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Transcription factor ZBP-89 is required for tryptophanhydroxylase 1 gene expression and serotonin production by Grasberger, H., Veniaminova, N., El-Zaatari, M., Hayes, M., Tessier, A., Merchant, J.L.

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Subcellular recruitment by TSG118 and TSPYL implicates a role for zinc finger protein 106 in a novel developmental pathway by Grasberger, Helmut, Bell, Graeme I.

“…To gain insight into the function of zinc finger protein 106 (ZFP106), we analyzed its subcellular targeting and identified its interacting proteins. Although…”
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A Novel Thyroid Hormone Receptor-β Mutation That Fails to Bind Nuclear Receptor Corepressor in a Patient as an Apparent Cause of Severe, Predominantly Pituitary Resistance to Thyroid Hormone by Wu, Sharon Y., Cohen, Ronald N., Simsek, Enver, Senses, Dursun A., Yar, Nese E., Grasberger, Helmut, Noel, Janet, Refetoff, Samuel, Weiss, Roy E.

“…Context: Resistance to thyroid hormone (RTH) is a dominantly inherited syndrome of variable tissue hyporesponsiveness to thyroid hormone (TH). Objective: We…”
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Repulsive Separation of the Cytoplasmic Ends of Transmembrane Helices 3 and 6 Is Linked to Receptor Activation in a Novel Thyrotropin Receptor Mutant (M626I) by Ringkananont, Usanee, Van Durme, Joost, Montanelli, Lucia, Ugrasbul, Figen, Yu, Y. Miles, Weiss, Roy E, Refetoff, Samuel, Grasberger, Helmut

“…Ligand-dependent activation of G protein-coupled receptors (GPCRs) involves repositioning of the juxtacytoplasmic ends of transmembrane helices TM3 and TM6…”
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Resistance to thyroid hormone in a patient with thyroid dysgenesis by Grasberger, Helmut, Ringkananont, Usanee, Croxson, Michael, Refetoff, Samuel

“…We report a patient with the unusual coincidence of two rare congenital disorders, lingual ectopy of the thyroid gland and resistance to thyroid hormone (RTH),…”
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Identification of a locus for nongoitrous congenital hypothyroidism on chromosome 15q25.3-26.1 by GRASBERGER, Helmut, VAXILLAIRE, Martine, PANNAIN, Silvana, BECK, John C, MIMOUNI-BLOCH, Aviva, VATIN, Vincent, VASSART, Gilbert, FROGUEL, Philippe, REFETOFF, Samuel

“…Permanent congenital hypothyroidism is the most prevalent inborn endocrine disorder, and principally due to developmental defects leading to absent, ectopic or…”
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Dual promoter structure of ZFP106: regulation by myogenin and nuclear respiratory factor-1 by Grasberger, Helmut, Ye, Honggang, Mashima, Hirosato, Bell, Graeme I.

“…The WD40 repeats containing zinc finger protein 106 (ZFP106) is a conserved mammalian protein of unknown function. However, its cDNA shares an extended region…”
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Autosomal Dominant Resistance to Thyrotropin as a Distinct Entity in Five Multigenerational Kindreds: Clinical Characterization and Exclusion of Candidate Loci by Grasberger, Helmut, Mimouni-Bloch, Aviva, Vantyghem, Marie-Christine, van Vliet, Guy, Abramowicz, Marc, Metzger, Daniel L., Abdullatif, Hussein, Rydlewski, Catherine, Macchia, Paolo E., Scherberg, Neal H., van Sande, Jacqueline, Mimouni, Marc, Weiss, Roy E., Vassart, Gilbert, Refetoff, Samuel

“…Context: Resistance to TSH (RTSH) is an inherited disorder of variable hyposensitivity to TSH. The metabolic consequences can range from euthyroid…”
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Loop variants of the serpin thyroxine-binding globulin: implications for hormone release upon limited proteolysis by Grasberger, Helmut, Golcher, Henriette M B, Fingerhut, Anja, Janssen, Onno E

“…Thyroxine-binding globulin (TBG) and corticosteroid-binding globulin are unique among non-inhibitory members of the superfamily of serine-proteinase inhibitors…”
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Effect of budesonide treatment on gestagen-induced hyperbilirubinemia in a patient with alagille syndrome by Otto, B., Grasberger, H., Beuers, U.

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Modularity of serpins. A bifunctional chimera possessing alpha1-proteinase inhibitor and thyroxine-binding globulin properties by Grasberger, H, Buettner, C, Janssen, O E

“…An exciting application of protein engineering is the creation of proteins with novel functions by the retrofitting of native proteins. Such attempts might be…”
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Characterization and primary structures of bovine and porcine thyroxine-binding globulin by Janssen, Onno E, Lahner, Harald, Grasberger, Helmut, Spring, Sabine A, Saller, Bernhard, Mann, Klaus, Refetoff, Samuel, Einspanier, Ralf

“…Thyroxine-binding globulin (TBG) is the major serum transport protein for iodothyronines in most of the large, omni- or herbivorous mammals. Characterization…”
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Characterization of the thyroxine-binding site of thyroxine-binding globulin by site-directed mutagenesis by Buettner, C, Grasberger, H, Hermansdorfer, K, Chen, B, Treske, B, Janssen, O E

“…The principal transport protein for T4 in human blood, thyroxine-binding globulin (TBG), binds T4 with an exceptionally high affinity (Ka = 10(10) M(-1)). Its…”
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Identification of thyroxine-binding globulin-San Diego in a family from Houston and its characterization by in vitro expression using Xenopus oocytes by JANSSEN, O. E, ASTNER, S. T, GRASBERGER, H, GUNN, S. K, REFETOFF, S

“…T4-binding globulin (TBG) is a liver glycoprotein that transports iodothyronines in serum. Several TBG variants with reduced T4 binding affinity have been…”
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RADIAL-VELOCITY OBSERVATIONS OF DT CYGNI by Grasberger, W. H., Herbig, G. H.

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