Search Results - "Grard, Marion"
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1
Homozygous Co-Deletion of Type I Interferons and CDKN2A Genes in Thoracic Cancers: Potential Consequences for Therapy
Published in Frontiers in oncology (24-06-2021)“…Homozygous deletion (HD) of the tumor suppressor gene CDKN2A is the most frequent genetic alteration in malignant pleural mesothelioma and is also frequent in…”
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2
Interplay between oncolytic measles virus, macrophages and cancer cells induces a proinflammatory tumor microenvironment
Published in Oncoimmunology (31-12-2024)“…Attenuated measles virus (MV) exerts its oncolytic activity in malignant pleural mesothelioma (MPM) cells that lack type-I interferon (IFN-I) production or…”
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High Oncolytic Activity of a Double-Deleted Vaccinia Virus Copenhagen Strain against Malignant Pleural Mesothelioma
Published in Molecular therapy. Oncolytics (25-09-2020)“…Malignant pleural mesothelioma (MPM) is a cancer of the pleura that lacks efficient treatment. Oncolytic immunotherapy using oncolytic vaccinia virus (VV) may…”
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4
Frequent Homozygous Deletions of Type I Interferon Genes in Pleural Mesothelioma Confer Sensitivity to Oncolytic Measles Virus
Published in Journal of thoracic oncology (01-05-2020)“…Oncolytic immunotherapy is based on the use of nonpathogenic replicative oncolytic viruses that infect and kill tumor cells exclusively. Recently, we found…”
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Oncolytic attenuated measles virus encoding NY-ESO-1 induces HLA I and II presentation of this tumor antigen by melanoma and dendritic cells
Published in Cancer Immunology, Immunotherapy (01-10-2023)“…Antitumor virotherapy stimulates the antitumor immune response during tumor cell lysis induced by oncolytic viruses (OVs). OV can be modified to express…”
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High oncolytic activity of a double deleted Vaccinia Virus Copenhagen strain against malignant pleural mesothelioma: Mesothelioma and oncolytic vaccinia virus
Published in Molecular therapy. Oncolytics (01-08-2020)“…Malignant pleural mesothelioma (MPM) is a cancer of the pleura that lacks efficient treatment. Oncolytic immunotherapy using oncolytic vaccinia virus (VV) may…”
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Journal Article