Search Results - "Grapsas, I."

Properties of a Bifunctional Bacterial Antibiotic Resistance Enzyme That Catalyzes ATP-Dependent 2‘‘-Phosphorylation and Acetyl-CoA-Dependent 6‘-Acetylation of Aminoglycosides by Azucena, Eduardo, Grapsas, Ioannis, Mobashery, Shahriar

“…An interesting enzyme confers resistance to a broad spectrum of aminoglycoside antibiotics primarily in Gram-positive bacteria. The enzyme was suggested to…”
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Loss of individual electrostatic interactions between aminoglycoside antibiotics and resistance enzymes as an effective means to overcoming bacterial drug resistance by Roestamadji, Juliatiek, Grapsas, Ioannis, Mobashery, Shahriar

“…Aminoglycoside-modifying enzymes modify the structures of aminoglycoside antibiotics, rendering them ineffective, a process which confers resistance to the…”
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Mechanism-Based Inactivation of Bacterial Aminoglycoside 3'-Phosphotransferases by Roestamadji, Juliatiek, Grapsas, Ioannis, Mobashery, Shahriar

“…The design, synthesis, and properties of the first mechanism-based inactivators for bacterial aminoglycoside 3'-phosphotransferases [APH(3')s], enzymes which…”
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Conjoint molecules of cephalosporins and aminoglycosides by Grapsas, Ioannis, Lerner, Stephen A., Mobashery, Shahriar

“…A general synthetic route to conjoint molecules of cephalosporins and aminoglycosides is described. These molecules were designed as potential substrates for…”
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N-(tert-butoxycarbonyloxy)-5-norbornene-endo-2,3-dicarboximide, a reagent for the regioselective introduction of the tert-butoxycarbonyl (BOC) protective group at unhindered amines : application to aminoglycoside chemistry by GRAPSAS, I, YOUNG JUNE CHO, SHAHRIAR MOBASHERY

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X-ray and NMR studies on the rotational isomerism about the C(5)-C(6) bond of 6-substitued methyl 2,3,4,-tri-O-acetyl-6-X-α-D-glucopyranoside derivatives by MENTZAFOS, D, POLISSIOU, M, GRAPSAS, I, HOUNTAS, A, GEORGIADIS, M, TERZIS, A

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X-ray and NMR studies on the rotational isomerism about the C(5)-C(6) bond of 6-substituted methyl 2,3,4,-tri-O-acetyl-6-X-α-D-glucopyranoside derivatives by Mentzafos, D., Polissiou, M., Grapsas, I., Hountas, A., Georgiadis, M., Terzis, A.

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